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Stroke: Rosuvastatin significantly slows the progression of atherosclerosis! Another proof of ASCVD prevention
Time of Update: 2022-09-15
Figure 1 The study, published in the Stroke study, confirms that for Chinese populations of subclinical atherosclerosis at low risk of ischemic cardiovascular disease (ICVD), rosuvastatin 20 mg/day can significantly slow the progression of carotid intimal media thickness (CIMT) after 2 years of treatment.
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Science sub-journal: Analysis of the neural coding mechanism under the social defects of mice with autism of "like the new and not tired of the old"
Time of Update: 2022-09-15
Social behavior is the basis for the survival and development of individuals and human society. There is no definitive answer to the scientific question of how the brain encodes information about soci
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Science PD Mechanism New Discovery: GPNMB drives pathological progression by promoting α-syn internalization
Time of Update: 2022-09-15
Multiple GWASs have linked chromosome 7 loci (rs199347) to PD, combined with GTEx databases [1, 2] and co-localization analysis, and the authors found that GPNMB exhibited the greatest overlap between PD risk and eQTL effects.
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Sci Adv Metastat: An axis mechanism that sets normal body weight and blood sugar
Time of Update: 2022-09-15
Metabolic syndromes such as diabetes and cardiovascular disease caused by obesity and obesity are common diseases that plague modern society, and metabolic disorders are common causes of obesity and m
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Science Uses Hormones to Improve Cognition: Gonadotropin-releasing hormone (GnRH) can save cognitive abilities in people with Down syndrome
Time of Update: 2022-09-15
If miR-200b is selectively overexpressed in the hypothalamic preoptic region (POA) of Ts65Dn male mice, how odor discrimination and cognition can be restored, while also increasing the number of Gnrh1 neurons.
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Frontiers Science Sub-Journal: Old Medicines Reveal New Targets for Treating Lung Cancer and Chronic Pain
Time of Update: 2022-09-15
▲If you have any business needs, please long press to scan the QR code above, or▎ WuXi AppTec content team editorWuXi AppTec provides integrated, end-to-end new drug development and production services to the global biopharmaceutical industry, covering chemical drug development and production, biological research, preclinical and clinical trial development, cell and gene therapy research and development, testing and production.
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Sci Adv's team discovered a novel electrical signal that maintains circadian rhythms
Time of Update: 2022-09-15
Circadian rhythms are coordinated and controlled by the brain's main biological clock, and its core is the molecular rhythm with a negative feedback cycle of 24 hours between the biological clock gene
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Mol Psychiatry-Yingfei Wang's research group revealed the role of KDM6B protein in neuronal synaptic plasticity and learning and memory
Time of Update: 2022-09-15
, Mol Psychiatry,2022）In order to further study the specific molecular mechanisms of synaptic transmission abnormalities and learning cognitive impairment in KDM6B-cKO mice, the researchers performed systematic RNA sequencing, analyzed and compared the mRNA expression of KDM6B-KO and normal neurons (WT) (Figure 3 A-D), and found a series of important KDM6B downstream regulatory genes, including vesicle glutamate transporter VGLUT2 and another family member VGLUT1.
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People who are "socially afraid" should be careful! Lack of social interaction can change brain structure and can also reduce life expectancy
Time of Update: 2022-09-15
Image source: 123RF For example, a review paper in the journal Perspectives on Psychological Science pointed out that social isolation, loneliness and a variety of health problems are highly correlated: these people are at higher risk of cardiovascular disease, metabolic disease and neurological disease.
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Winter is heavy and summer is light, seasonal mood disorder! Scientists reveal that hypothalamic neural circuits respond to seasonal light changes
Time of Update: 2022-09-15
8, eabn9867 (2022) ,Seasonal changes in day length induce multisynaptic neurotransmitter switching to regulate hypothalamic network activity and behaviorThe pictures in the article are from referencesClick on the blue word to follow usSeasonal changes related to the solar cycle, such as sleep, eating, and mood, are closely related: shorter daytime in winter is associated with seasonal affective disorder, which is characterized by regular depression in winter and mild remission in summer.
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Biomaterials Air Force Military Medical University Huang Jinghui/Luo Zhuojing and others have developed and built a new oxygen supply system to promote peripheral nerve regeneration
Time of Update: 2022-09-15
Taken together, the study found that sequential oxygen supply systems provide the necessary insights for oxygen regulation of biological materials and highlight the potential of oxygen delivery strategies as a therapeutic approach to repair defects in peripheral nerves and other aerobic tissues.
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The Team of Sci Adv Wu Haitao/Chen Liangyi/Zhang Jue collaborated to reveal the neural coding mechanism of social behavioral deficits in mice with autism
Time of Update: 2022-09-15
Social behavior is the basis for the survival and development of individuals and human society. There is no definitive answer to the scientific question of how the brain encodes information about soci
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How does an injured brain recover on its own? BGI successfully built the world's first spatio-temporal map of brain regeneration
Time of Update: 2022-09-15
On September 2, 2022, BGI Life Sciences Research Institute, together with the team of Professor Fei Jifeng of Guangdong Provincial People's Hospital and the team of Professor Chen Liang of Wuhan Unive
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NBE (IF=29) The team of ShengXing and others at Tsinghua University has developed bioresorbable thin-film silicon diodes for photoelectric excitation and inhibition of neural activity
Time of Update: 2022-09-15
Specifically, silicon-based thin film pn diodes produce light-induced positive and negative electric fields, which, when the membrane comes into contact with cultured neurons, leads to photo-induced cell depolarization and hyperpolarization and regulation of intracellular calcium dynamics.
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Science: Why do queens have so many children and grandchildren to live longer? The latest research reveals the secret of extending the life of ants by a factor of 5
Time of Update: 2022-09-15
They subsequently found that the increased insulin in the body of the new queen induces ovarian development and then begins to produce an insulin-suppressing protein called Imp-L2, which helps reduce AKT phosphorylation in the fat body and ovaries, blocking AKT signaling, thereby prolonging the lifespan of the ants.
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Nat Commun Chen's team reveals the circuits and molecular mechanisms underlying the involvement of lower support in the pathogenesis of temporal lobe epilepsy
Time of Update: 2022-09-15
Written by Fei FanEditor-in-charge - Wang SizhenEditor — Binwei YangEpilepsy is one of the most common disorders of the nervous system, affecting nearly 1 percent of the global population and nearly o
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Nature sub-journal: "Electricity" can improve memory, and the effect can last for one month!
Time of Update: 2022-09-15
For middle-aged and elderly people aged 40 years and older who have no underlying health problems, they may benefit from a small amount of alcohol consumption (1-2 standard cups per day), including reduced risk of cardiovascular disease, stroke, diabetes, etc.
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Stand up and faint? Some people have not been diagnosed with the disease for more than 20 years...
Time of Update: 2022-09-15
The doctor did a full face examination and said, "Are you too anxious?" "Why do you faint when you stand?" In February, Lindsey was finally diagnosed with Postural Tachycardia Syndrome (PoTS), an orthostatic intolerance with clinical manifestations of orthostatic tachycardia.
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Cereb Cortex—Anatomical Subtype Mining and Analysis of The Heterogeneity of Schizophrenia
Time of Update: 2022-09-15
In addition, using image-transcriptome association analysis, the researchers further explored the potential heterogeneous biological factors in schizophrenia suggested by the two subtypes, providing prospective clues for related studies.
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Express treatment of fatal neurodegenerative diseases, gene therapy early clinical data is gratifying
Time of Update: 2022-09-15
▲If you have any business needs, please long press to scan the QR code above, or▎ WuXi AppTec content team editorRecently, Forge Biologics released preliminary data on the Phase 1/2 clinical trial OF RESKUE conducted by its novel gene therapy FBX-101 in patients with Krabbbe disease.
