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Neurology: low blood pressure, body mass index, non-HDL cholesterol and risk of dementia in later life
Time of Update: 2022-10-02
A recent study published in Neurology explored whether a combination of low values of low systolic blood pressure (SBP), body mass index (BMI), and non-HDL in later life was associated with a higher risk of dementia compared to the low values of these risk factors.
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Can postherpetic neuralgia be completely cured: a three-tiered treatment regimen for postherpetic neuralgia
Time of Update: 2022-10-02
The common feature of the above non-neurodestructive methods for the treatment of PHN is to regulate the neural function of peripheral and central sensitization under the principle of "no injury", relieve pain, shorten the course of the disease, reduce systemic medication and adverse drug reactions, reduce long-term medical resource consumption, and improve the quality of life of patients.
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Neurology: stroke onset, lateral branch score, and functional outcomes after intravascular therapy for acute ischemic stroke
Time of Update: 2022-10-02
A recent study published in Neurology evaluated the relationship between CT angiography (CTA) time and quantitatively determined lateral branch scores, and whether the lateral branch score altered the relationship between retransmission time and functional outcomes.
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Using scientific research to eradicate oblivion | a selection of papers on World Alzheimer's Day
Time of Update: 2022-10-02
September 21 is World Alzheimer's Day, and in order to raise public awareness of the disease and promote related research, we have selected Alzheimer's disease-related research papers from Cell, Neuron, Developmental Cell and Cell Reports from Cell Press's journal series, including chaperone-mediated autophagy Autophagy, CMA), Tau protein lesions and nucleoplasmic transport, microglia proliferation and β amyloid accumulation and other organic research, but also includes transcriptomics and genetic sequencing, 3D cell models, neurological disease imaging and other methodological applications and breakthroughs.
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JNNP: "Glial hyperplasia only" pre- and postoperative memory in patients with hippocampal sclerosis, a paired case-control study
Time of Update: 2022-10-02
Based on the structural and functional relationship between mLLE hippocampal pathology and memory, it is hypothesized that GO patients should exhibit several, more non-specific, and bilateral memory impairment before surgery than HS patients.
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Neurology: Parkinson's disease, insufficient exercise of cognitive function, or dementia
Time of Update: 2022-10-02
The main objective of the study (1) was to assess whether patients with cognitive IADL disorder as defined in FAQQ (cutoff >1) have a higher risk of PDD development and to determine whether the combination of PD-MCI and cognitive IADL disorder is more predictable for conversion to PDD than the presence of either marker alone.
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J Neurosci—Li Shao/Ma Tonghui's team revealed the orthogonal array structure of AQP4 in aquaporin point mutations in mice and reduced their polar distribution at the end of astrocytes
Time of Update: 2022-10-02
On September 13, 2022, Professors Li Shao and Ma Tonghui of the School of Basic Medicine of Dalian Medical University published an online publication entitled "AQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized" in the Journal of Neuroscience, an authoritative journal of neuroscience Expression of AQP4 Protein in Astrocytic Endfeet at the Blood-Brain Barrier" research paper.
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Neurology: What is the relationship between AD CSF indicators and alpha-synuclein
Time of Update: 2022-10-02
The results showed that the accompanying pathological changes in αSyn in AD patients were associated with lower CSF p-tau181, t-t-tau, and Ng levels, and could affect the diagnostic accuracy of AD patients.
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JNNP: Postural illusion is a biomarker of persistent postural perceptual vertigo
Time of Update: 2022-10-02
Patients and healthy control groups that resulted in "objective" instability due to BV showed perceptual instability proportional to actual swings.
Patients and healthy control groups that resulted in "objective" instability due to BV showed perceptual instability proportional to actual swings.
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Overview of anatomical and related changes in the ventricles and cerebrontine system
Time of Update: 2022-10-02
(Right) 33-year-old patient with headache, axial T1WI C+ showing uneven strengthening of the left ventricle body "foam-like" lesion.
(Right) 33-year-old patient with headache, axial T1WI C+ showing uneven strengthening of the left ventricle body "foam-like" lesion.
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What happens to the thickening of the extraocular muscles? How to identify?
Time of Update: 2022-10-02
Image manifestations: abdominal thickening, tendon not thickening, lower rectus, internal rectus, superior rectus muscle involvement is more common, enhance the scanning of the extraocular muscle can see different degrees of strengthening.
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World Alzheimer's Day Primary progressive aphasia and its subtyping
Time of Update: 2022-10-02
2. Semantic primary progressive aphasia (svPPA) (1) Clinical diagnosis At least one of the following core symptoms is met: (1) Naming disorder; (2) Impaired comprehension of a single word.
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[Recommended] Several syndromes of neurosurgery
Time of Update: 2022-10-02
Disorders of vertical isotropic movement of the eyeball caused by superior thalamic lesions (mostly pineal gland tumor compression of the midbrain quadruplex), paralysis of upward gaze, and loss of pupillary reflex to light (impaired upper thalamus); Neurological deafness (damage to the lower hilum); Cerebellar ataxia (damage to the binding arm).
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Front. Neurol: Clinical variability of SYNJ1-related early-onset Parkinson's disease
Time of Update: 2022-10-02
Single gene mutations can lead to PD, where early-onset autosomal recessive inheritance PD (AREO PD) is clinical and genetically heterogeneous – it is most commonly caused by mutations in the PRKN, PINK1, and DJ-1 genes, especially in patients with a positive family history or/blood relationship, with a special phenotype such as slow disease progression; But rare mutations in genes such as SYNJ1 can lead to more serious diseases, such as additional neurological symptoms – cognitive decline, epilepsy, etc.
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Neurology: The relationship between self-reflection, cognition, and brain health in older adults with unimpaired cognitive function
Time of Update: 2022-10-02
The association between self-reflex and AD-sensitive markers (global cognition, glucose metabolism, and amyloid deposition) is assessed by unadjusted and adjusted regression.
The association between self-reflex and AD-sensitive markers (global cognition, glucose metabolism, and amyloid deposition) is assessed by unadjusted and adjusted regression.
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Prevention of Alzheimer's disease, starting from adolescence ...
Time of Update: 2022-10-02
AD can be preventedControlling controllable risk factors is the key to Professor Cui Mei, because AD lacks effective treatment methods and the disease development is irreversible, so early prevention is particularly important.
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【One case per day 422 stage】Chronic hepatic encephalopathy
Time of Update: 2022-10-02
【Diagnostic Points】In patients with chronic hepatic encephalopathy, bilateral basal ganglion T1WI high signal, especially in bilateral globulus pallidus;T1WI high signal can also occur in the substantia nigra;The incidence of the above abnormal manifestations in patients with chronic liver failure is about 80% to 90%;It is currently agreed that it is caused by the accumulation of manganese in the human body.
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Please stop glorifying Alzheimer's, Alzheimer's risk is related to weight
Time of Update: 2022-10-02
In the male population, low body weight alone is significantly associated with an increased risk of developing dementia.
In the male population, low body weight alone is significantly associated with an increased risk of developing dementia.
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Data analysis of more than 8 million hospitalizations in China: Is it only wallets that hurt the stock market? It's really sad! Stock volatility is associated with CVD hospitalization rates!
Time of Update: 2022-10-02
The daily absolute return of the Shanghai or Shenzhen index correlates significantly with the increase in hospital admissions for total CVD, ischemic heart disease, stroke and heart failure nationwide (Figure 4).
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Figure 6 Table 1 The etiology, pathogenesis, diagnosis and treatment of cardiogenic stroke, all in one!
Time of Update: 2022-10-02
： ， 。 Video Mini Program like, tap twice to cancel like in viewing, tap twice to cancel in viewing Cardiogenic embolic stroke (CES), abbreviated as cardiogenic stroke, refers to a clinical syndrome in which emboli from the heart and aortic arch circulate through the circulation of cerebral arteries causing corresponding brain dysfunction.
