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JNNP: "Glial hyperplasia only" pre- and postoperative memory in patients with hippocampal sclerosis, a paired case-control study

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Hippocampal sclerosis (HS) is the most common histopathological manifestation of drug-resistant medial temporal lobe epilepsy (mTLE), and its clinical features, pathogenesis, epilepsy occurrence, and treatment outcomes have been thoroughly studied

MRI allows to distinguish between HS and GO

Frequency of preoperative memory impairment

MRI allows to distinguish between HS and GO

Changes in individual memory from preoperative to postoperative evaluation

Functional differences between GO and HS have not been resolved but are relevant

The clinical differences were obvious, with the GO group having a late age of seizures (18±12 vs 12±9 years) and fewer postoperative seizures (63% vs 82%)

Preoperative memory manifestations and postoperative memory outcomes

Compared with HS, GO is characterized by (1) a later seizure, (2) less pronounced and non-specific memory damage before surgery, (3) less successful surgical results, and (4) more significant

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