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CMI (IF=22) Chen Hualan/Li Chengjun, Chinese Academy of Agricultural Sciences, discovered a new regulatory mechanism for the replication cycle of influenza A virus
Time of Update: 2022-09-15
iNatureAs a major component of the viral ribonucleoprotein (vRNP) complex in influenza A virus (IAV), the nuclear protein (NP) interacts with the isomers of the input protein α family members, leading to itself and the vRNP complex into the nucleus, a key process in the IAV replication cycle.
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Cell | over 100 strains! Design and construction of ultra-complex synthetic intestinal microbial communities
Time of Update: 2022-09-14
The researchers successfully constructed a synthetic microbial community with a well-defined composition, high complexity (containing 119 strains) that more effectively reflected the role of the human gut microbiota.
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【Cover】Damage to intestinal bacteria is related to the reduced survival rate of organ transplant recipients| Science and Translational Medicine
Time of Update: 2022-09-07
Welcome to pay attention to the official public account of Science, click "Read the original article" to visit the original English text to light up your "like" for medical researchClick on the blue word above to follow usBased on a new study of samples containing more than a thousand liver or kidney transplant recipients, scientists have linked the destruction of gut bacteria to reduced survival after organ transplantation.
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Cell Sub-Journal: Intestinal symbiotic bacteria are involved in new mechanisms of intestinal homeostasis regulation
Time of Update: 2022-09-07
The researchers found that metabolites smaller than 3KD in the cultured supernatant of the bacterium had a direct induction dc immune tolerance effect, and demonstrated that one of the metabolites, choline, could induce DC's immune tolerance to Treg differentiation through upregulation of α7nAChR-mediated RA and TGF-β, thereby protecting mice from tolerable DSS-induced colitis.
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Zheng Heping/Yang Bin team of Southern Medical University developed a new method for syphilis detection based on Cas13a
Time of Update: 2022-08-20
To meet the need for improved syphilis diagnosis, the research team combined PCR technology with CRISPR-LwCas13a technology to achieve in vitro detection technology with high sensitivity and specificity for different templates .
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Break through key barriers!
Time of Update: 2022-08-20
In a new proof-of-concept study published in Cell on August 4, 2022, a team of researchers from the University of California, San Diego broke through this key hurdle by engineering natural large intestines derived from mouse and human guts Bacillus, and then implanting the modified engineered native bacteria into mice induced persistent physiological changes that ameliorated chronic pathological conditions such as diabetes in animals .
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Nature's "superbug nemesis" - the dual bactericidal mechanism of teixobactin
Time of Update: 2022-08-20
Next, the authors used ssNMR to determine the teixobactin-lipid II interface, which consists of a conserved pyrophosphate (GlcNAc-MurNAc-PPi) moiety and a pentapeptide whose variation confers resistance to glycopeptide antibiotics such as vancomycin 【5】.
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Yuan Huijuan + Zhang Chenhong et al: A new mechanism of gut microbiota regulating intergenerational genetics to prevent diabetes
Time of Update: 2022-08-19
837] ① A high-fat diet was used to establish a model of hyperglycemia during pregnancy, and caesarean section and cross-feeding were used to study the effect of vertical transmission of intestinal flora on glucose metabolism in offspring; ② The changes in intestinal flora caused by abnormal maternal glucose metabolism would affect the intestinal flora of offspring through vertical transmission.
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Heavyweight "Scientific Review of Probiotic 'Dose-Response Relationship'" Released
Time of Update: 2022-08-19
In 2021, the Probiotics Branch of the Chinese Society of Food Science and Technology formally established the research project "Scientific Review of Probiotics' Dose-Effect Relationship", with a view to providing technical reference for the health effect, dosage index and industrial application of probiotics in China's standard regulations .
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The 13th National Symposium on Microbial Resources August 18-19
Time of Update: 2022-08-19
com Secretary of the conference affairs group: Zhang Zhenting 13116380080, Liu Tao 18871450275 Professional Committee of Microbial Resources of Chinese Society for Microbiology Microbial resources are an important material basis for human survival and development, an important source of technological innovation in life sciences, an important productive force in the fields of health, food, and the environment, and an important strategic biological resource .
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Domestic team: Bacillus coagulans combined with chitosan oligosaccharide may improve colitis in mice
Time of Update: 2022-08-19
Recently, Peng Nan and his team from Chengdu University/Huazhong Agricultural University published a new study on the Microbiology spectrum, using DSS to induce a colitis model in mice.
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Beware of "gynecological inflammation" due to high temperature in dog days!
Time of Update: 2022-08-19
Be vigilant with the high incidence of gynecological diseases in hot summer With the arrival of the summer rainy season, bacteria will multiply in a high temperature and humid environment, especially women are easily infected by external pathogens, and a little carelessness will induce bacterial growth .
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Summer sports season is coming to probiotics to help your fat loss goals!
Time of Update: 2022-08-15
Lactobacillus casei Zhang can improve lipid metabolism Probiotics, as important probiotics, can effectively regulate the intestinal flora of people with obesity caused by dietary changes .
Lactobacillus casei Zhang can improve lipid metabolism Probiotics, as important probiotics, can effectively regulate the intestinal flora of people with obesity caused by dietary changes .
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The latest research and application forum of Epigenetics was successfully held. Ketuo Bio led the "Formidable Epigenetics"
Time of Update: 2022-08-15
On May 28th, the GUT 2022 x 4th China Gut Industry Conference · Postshengyuan Latest Research and Application Forum, jointly organized by Beijing Ketuo Hengtong Biotechnology Co. , Ltd. and enthusias
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Oral administration of pasteurized probiotic fermented milk alleviates DSS-induced inflammatory bowel disease in rats
Time of Update: 2022-08-15
It was found that gavage of pasteurized probiotic fermented milk and common fermented milk significantly decreased the DAI score of IBD rats ( PPP < 0.
It was found that gavage of pasteurized probiotic fermented milk and common fermented milk significantly decreased the DAI score of IBD rats ( PPP < 0.
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A Preliminary Study on the History of Fermented Milk in the World
Time of Update: 2022-08-15
In conclusion, more archaeological evidence from Africa and the Middle East is needed to trace the origin of fermented dairy products .
In conclusion, more archaeological evidence from Africa and the Middle East is needed to trace the origin of fermented dairy products .
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Gut dysplasia affects early microbiota establishment, driving autism in mice
Time of Update: 2022-08-15
Wang Qian, Zhou Hongwei, etc. : Intestinal dysplasia affects the establishment of early microflora and drives Brain Behavior and Immunity of autism in mice [IF:7. 217]① The autism spectrum disorder (
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Gut microbiota may be linked to increased heart disease risk from red meat consumption
Time of Update: 2022-08-15
Arteriosclerosis, Thrombosis, and Vascular Biology [IF:10. 514]① 3931 adult subjects in the US community were included to evaluate the association between animal-derived food (ASF) and the risk of at
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Lock in today's 2 pm probiotics science knowledge contest grand opening
Time of Update: 2022-08-15
Accompanied by probiotics On June 16th, Ketuo Biology x China Society of Food Science and Technology Invite you to pay attention to the grand opening of the 2nd "Ketuo Bio Cup" Probiotics Science Knowledge Competition Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Network .
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Microbes hold the secret to eternal youth: improving cognition
Time of Update: 2022-08-15
Third, a healthy, balanced diet can help keep the brain from "rusting", and even increasing coffee intake can reduce the risk of Alzheimer's disease, which keeps gut microbes away from producing toxins and inflammation .