-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
| The health effects of probiotics on the human body have a certain dose-response relationshi. However, due to the differences of strains in the health effects of probiotics, there is no unified requirement for the intake of probiotics in domestic and foreign standards and regulation. In 2021, the Probiotics Branch of the Chinese Society of Food Science and Technology formally established the research project "Scientific Review of Probiotics' Dose-Effect Relationship", with a view to providing technical reference for the health effect, dosage index and industrial application of probiotics in China's standard regulation. After nearly 8 months of research and improvement, the "Scientific Review of Probiotics' Dose-Effect Relationship" was formed and officially released at the 17th International Symposium on Probiotics and Health held by the Chinese Society of Food Science and Technolog. "Sufficient quantity" is one of the three core characteristics of probiotic. Studies have found that there is a certain dose correlation between probiotics and the health effects of the hos. For probiotics to reach the target of human action, they need to pass through multiple biological barriers, and satisfying a certain number of viable bacteria is the key factor for their healthy effec. The number of viable bacteria in probiotic-related products has become one of the focuses of the industry's R&D and innovation proces. The accurate count of viable bacteria at the strain level is an important technical condition for measuring the dosage ofprobiotic. It has become an industry consensus to indicate the number of viable bacteria in the shelf life of probiotics on the labels of probiotic-related product. According to the stability of probiotic raw materials and the actual amount of strains added in the production process, the number of viable bacteria of probiotic strains in the product can be preliminarily determine. The accurate count of viable bacteria at the strain level using multi-technology combined is an important technical means to measure the dose of probiotics, and it is also an important basis for China's market to monitor whether the number of viable bacteria in the shelf life of probiotic-related products meets the requirement. The recommended intake of probiotics in existing research literature and relevant international standards and regulations is mainly concentrated in 107~1011 CFU/d. The core function of probiotics is to improve human intestinal health, and its effect on intestinal health has a certain dos. dependencie. The recommended intake of probiotics is mainly concentrated in 107~1011CFU/d in the application guidelines of probiotics, clinical research literature and relevant international standards and regulation. With the innovative application of probiotics in diversified products and the emergence of next-generation probiotics, clarifying the recommended intake of probiotics is conducive to promoting the standardized development of the probiotics industr. The healthy dose of probiotics has strain differences, and the higher the dosage, the better Since the efficacy of probiotics is specific to strains and populations, the effective dose of each probiotic is different, and some strains can also play a healthy role at lower dose. Therefore, during the development of probiotic strains, attention should be paid to their biological Research on the scientific characteristics, clarify the healthy dose of the target strain in the product, and avoid falling into the misunderstanding that the higher the amount of probiotics, the bette. The clinical dose of probiotics in different types of food is relatively stable. Differences in food processing methods, matrix components, and storage methods will affect the activity of probiotics to a certain exten. For foods containing probiotics, it is necessary to assess the shelf-life stability of the strain under the storage conditions indicated on the product labe. There are differences in the amount of probiotics added to different food. Based on the current research findings, the general food matrix has no substantial impact on the health effects of probiotics, and the health effects of probiotics in different types of foods are relatively stabl. The health effects of probiotics are not dependent on the number of strains, and should be based on scientific research on the interaction between strain. At present, the health effects of multi-strain probiotics have received extensive attention from the scientific and technological circles and the industr. Studies have shown that the health effects of multi-strain compounding will be affected by factors such as compounded strains and target population, and there is no obvious strain-combination quantity dependenc. The research on the compounding of probiotic strains must be based on the scientific research on the interaction between the strain. It is necessary to consider not only the cross-mutualization and synergy between the strains, but also whether there is competition or synergy between the compounded strain. Antagonistic relationshi. |
