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The latest achievement of Cao Yunlong's team: XBB.1.5 transmissibility enhancement is jointly promoted by strong binding of ACE2 and antibody escape, and neutralizing antibody SA55 still has strong activity against XBB.1.5
Time of Update: 2023-02-03
style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;">The author of this article BioTalker*For medical professionals onlyJust now, the team of Cao Yunlong of Peking University published the latest research results on XBB.
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University of Queensland Water Centre Guo Jianhua team Adv. Sci.: Unlocking the new role of plasmids—regulating antibiotic-induced changes in bacterial morphology
Time of Update: 2023-02-03
First author: Yu ZhigangCorresponding author: Guo JianhuaNewsletter: Australian Centre for Water and Environmental Biotechnology (ACWEB), University of QueenslandPaper DOI: 10. 1002/advs. 202203260Nat
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Scientific research progress│New progress has been made in the study of the basic regulation and evolutionary pathways of the specific reproductive mode of the main pathogen taxa of fungi and meningitis where microorganisms are located
Time of Update: 2023-02-03
On December 24, 2022, the research team of Wang Linqi, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, published an article entitled "Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen" in Nature Communications.
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Zhang Ruifu Research Group of Nanjing Agricultural University Adv. SCI: The simplest rhizosphere synthetic flora inhibits the assembly process and mechanism of action of Fusarium species
Time of Update: 2023-02-03
Keywords: species-borne pathogenic bacteria, rhizosphere core strains, simplified synthetic flora, synergistic and efficientThe rhizosphere microbiome plays an important role in plant growth and health, and regulating the rhizosphere microbiome can promote plant growth and improve the ability of plants to tolerate environmental stresses.
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Rewrite the textbook! Science: Changes in gene expression in E. coli occur almost exclusively during the transcriptional phase of cell growth
Time of Update: 2023-02-03
Since the advent of systems biology 20 years ago, scientists have tried to determine how cells regulate transcription and translation processes based on gene expression data: which mRNAs and proteins are produced under what conditions.
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【Nature sub-issue】Two articles in a row! Ma Yingfei's team excavated human intestinal archaea virus; Development of high-throughput preparation of chassis bacteriophages
Time of Update: 2023-02-03
Recently, the team of Ma Yingfei of Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, published a research paper entitled "Metagenomic analysis reveals unexplored diversity of archaeal virome in the human gut" in Nature Communications 。 The study found a high diversity of human gut archaea and archaeal viruses, and this study will help to better characterize archaeal viruses in the human gut and their archaeal hosts, and provide a complementary view of the human gut microbiome.
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Gaofu team, first article in 2023
Time of Update: 2023-02-02
"Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs", the study The structure of the RshSTT182/200 receptor-binding domain (RBD) and human angiotensin-converting enzyme 2 (hACE2) complexes was determined, and key residues affecting receptor binding were identified.
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【Nature】The weakness of the new crown virus has been found! Boston University and Harvard Medical School open new ways to eliminate COVID
Time of Update: 2023-02-01
Referrals, live broadcasts/events01/12 14:00-16:00 OnlineOlink Multiomics Cohort ForumScan the code to participate for free03/02-03 09:00-18:00 ShanghaiThe 2nd Yangtze River Delta Single-cell Omics Technology Application ForumScan the code to participate for freeThis article is the original of Translational Medicine Network, please indicate the source for reprintingWritten by JevinThe new coronavirus usually infects humans through the respiratory tract and causes damage to the respiratory system and various organs of the human body.
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XBB strains are pathogenic or lower! The team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, found that XBB acquired a new mutation with low cell lethality that was less toxic than other Omicron mutant strains
Time of Update: 2023-02-01
The toxicity of the T11A mutant envelope protein was significantly reducedBased on the above results, the researchers believe that the pathogenicity of the XBB strain will be further weakened compared with the previous Omicron subvariant.
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Nature sub-issue: Analysis of the working mechanism of the new CRISPR antiviral system in bacteria
Time of Update: 2023-01-06
On October 27, 2022, in a new study published in Nature Microbiology, Zhang Heng's team from Tianjin Medical University and the Wuhan Institute of Virology, Chinese Academy of Sciences By analyzing the cryo-EM structure of Cas7-11 complexes in different states, Deng Zengqin's team used a large number of biochemical experiments to elucidate the mechanism of Cas7-11 processing precursor CRISPR RNA (pre-crRNA) and identifying and cleavaging target RNA.
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Nature: The chances of discovering the ancestors of the new coronavirus are "almost zero"
Time of Update: 2023-01-06
The complete genomes of the novel coronavirus (SARS-CoV-2) and several closely related bat coronaviruses suggest that they shared a common ancestor decades ago, but these coronaviruses exchange RNA fragments with each other, a process known as recombination, so each part has its own evolutionary history.
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Nature sub-issue: Analysis of the working mechanism of the new CRISPR antiviral system in bacteria
Time of Update: 2023-01-06
On October 27, 2022, in a new study published in Nature Microbiology, Zhang Heng's team from Tianjin Medical University and the Wuhan Institute of Virology, Chinese Academy of Sciences By analyzing the cryo-EM structure of Cas7-11 complexes in different states, Deng Zengqin's team used a large number of biochemical experiments to elucidate the mechanism of Cas7-11 processing precursor CRISPR RNA (pre-crRNA) and identifying and cleavaging target RNA.
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Nature: The chances of discovering the ancestors of the new coronavirus are "almost zero"
Time of Update: 2023-01-06
The complete genomes of the novel coronavirus (SARS-CoV-2) and several closely related bat coronaviruses suggest that they shared a common ancestor decades ago, but these coronaviruses exchange RNA fragments with each other, a process known as recombination, so each part has its own evolutionary history.
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A review of Trends in Microbiology: Intraspecific, interspecific and cross-border signal communication mediated by population-sensing DSF
Time of Update: 2023-01-01
▲Click the blue text above to follow CellPress Cell Science▲Life SciencesLife scienceRecently, Trends in Microbiology, a review journal of Cell Press Cell Press, published online a review article by P
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Researchers reveal how Helicobacter pylori "went out of Africa"
Time of Update: 2023-01-01
Recently, Daniel Falush, a researcher at the Shanghai Pasteur Institute of the Chinese Academy of Sciences, collaborated with the University of Oslo in Norway to publish an online report entitled Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious in Nature Communications The mutations' research paper reports the unique evolutionary history of several new Helicobacter pylori African lineages "out of Africa" and gradually replacing local lineages in Europe and the Middle East.
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PNAS China Agricultural University reveals novel mechanism of high ammonium nitrogen fixation by Bacillus (non-leguminous nitrogen-fixing bacteria).
Time of Update: 2023-01-01
Expressionregulation mechanism of sabinae T27 nitrogen-fixing gene at different ammonium concentrationsProfessor Chen Sanfeng is the corresponding author of the research paper, Professor Ray Dixon of the JIC Research Center in the UK is the co-corresponding author, and Li Qin, a postdoctoral fellow at China Agricultural University is the first author.
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Fu Aigen's team at Northwestern University revealed the molecular mechanism of Chlamydomonas reinin's resistance to bright light
Time of Update: 2023-01-01
Recently, Professor Fu Aigen of Northwest University published a report entitled "Immunophilin CYN28 is required for accumulation of photosystem II and thylakoid FtsH protease in Chlamydomonas" online in Plant Physiology The paper is the first to report a molecular mechanism by which the pro-immune protein CYN28, localized in the thylakoid lumen, is involved in Chlamydomonas against high light.
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NSR(IF=23) Baoli Zhu/Fu Gao, Chinese Academy of Sciences, unveiled the temporal dynamics of drug-resistant enteric salmonella and dominant serum variants in China
Time of Update: 2023-01-01
Temporal and spatial changes of antimicrobial resistance in NTS in China (National Science Review) The emergence and spread of antibiotic resistance (AMR) in the Enterobacteriaceae family pose a serious threat to human and animal health.
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Significant differences between plant-fungal interspecific interaction patterns in aboveground and underground habitats in eastern China
Time of Update: 2023-01-01
Recently, the research group of Chu Haiyan of the Nanjing Institute of Soil Science, Chinese Academy of Sciences, and a number of scientific researchers inside and outside the United Nations published a report entitled "China Life Sciences Plant and fungal species interactions differ between
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Effector proteins that help fungi invade multiple host plants
Time of Update: 2023-01-01
Recently, a research group of professors at the University of Córdoba in Spain published an online report entitled Conserved secreted effectors contribute to endophytic growth and multihost plant compatibility in a at The Plant Cell The Vascular Wilt Fungus paper reveals that Fusarium oxysporum, the blight-inducing fungus, secretes a group of effector proteins that enable it to colonize the roots of a variety of plants.
