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Escherichia coli is a "well-known" opportunistic pathogen
Previously, synthetic biologists genetically engineered bacteria in the lab to perform various biological functions, but once back in the gut, the engineered bacteria became "Schrödinger's bacteria," and the result was basically no results
In theory, native bacteria can maximally adapt to the host luminal environment, bypassing almost all barriers to colonization, making them ideal engineered bacteria for gene delivery
A single implant of a native engineered E.
Previously, synthetic biologists genetically engineered bacteria in the lab to perform various biological functions, but once back in the gut, the engineered bacteria became "Schrödinger's bacteria," and the result was basically no results
In theory, native bacteria can maximally adapt to the host luminal environment, bypassing almost all barriers to colonization, making them ideal engineered bacteria for gene delivery
A single implant of a native engineered E.
https://doi.