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Nature: The new crown can change the immune system, or cause an excessive immune response
Time of Update: 2023-02-03
The study showed that after infection with the new crown, even mild symptoms can change the immune status of men, making men respond more strongly to the flu vaccine, indicating that after infection, when faced with other viruses, men trigger a stronger inflammatory response, leading to more pronounced functional changes in the male immune system, even long after recovery.
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iScience: Genome sequencing of endangered sharks
Time of Update: 2023-02-03
Image: Scientists have sequenced the genomes of hammerhead sharks and shortfin mako sharks at the chromosomal level, showing that their populations declined more than 250,000 years ago.
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Nature: The key to the transformation of chronic blood cancers into aggressive diseases
Time of Update: 2023-02-03
The researchers also tested a drug compound that inhibits DUSP6 and found that this compound (used only in animal studies) prevented the progression of chronic disease to aggressive disease in two different mouse models of cancer and in mice with human tumors sampled from patients.
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Nature Cancer: Triple immunotherapy holds promise for treating pancreatic cancer
Time of Update: 2023-02-03
1038/s43018-022-00500-z Researchers at the University of Texas MD Anderson Cancer Center have discovered a novel pancreatic cancer immunotherapy combination that targets T cell checkpoints and myeloid suppressor cells, successfully reprogrammed the tumor immune microenvironment (TIME), and significantly improved anti-tumor responses in pancreatic cancer models.
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Gao Ge's team proposed a new method for cross-modal representation learning
Time of Update: 2023-02-03
Biological processes in cells involve DNA, RNA, proteins and other different levels of regulation, which influence each other and work together, so integrating multimodal information corresponding to
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Flu or cold? A home smart device can help you
Time of Update: 2023-02-03
"Our microresonators are about 100 times better than previous resonators used for longwave infrared spectroscopy," Dingding Ren said.
"Our microresonators are about 100 times better than previous resonators used for longwave infrared spectroscopy," Dingding Ren said.
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Dual-acting macromolecules: new ideas for cancer drug design
Time of Update: 2023-02-03
A fundamental challenge in drug development is how to balance "optimizing the drug's match to the target" with "the drug's ability to cross the cell membrane and reach the target. " In traditional dr
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New progress has been made in the study of leucine-regulated autophagy
Time of Update: 2023-02-03
Recently, the research results of Professor Yan Xianghua's team from the National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory and the Frontier Science Center for Animal Bre
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Nature of Central South University published an article: A novel metabolic mechanism of iron death in tumor cells
Time of Update: 2023-02-03
Professor Yang Minghua's team of Pediatrics from the Third Xiangya Hospital of Central South University published original research results entitled "The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis" in the international authoritative academic journal Nature Communications, revealing the novel metabolic mechanism of iron death in tumor cells.
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Nature: Chinese scientists led the discovery of 1 protein that can "ignite" brain leptin
Time of Update: 2023-02-03
To find strategies to help people reach and maintain a healthy weight, researchers at Central South University's Xiangya Second Hospital, Baylor College of Medicine, and the University of Texas San Antonio Health Science Center investigated how activity is regulated by leptin, which is involved in controlling appetite and energy expenditure.
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Nature publishes two articles in a row: the new technology "FIND-seq" detects cells that were previously difficult to distinguish
Time of Update: 2023-02-03
To address this problem, a team led by researchers at Brigham and Women's Hospital, one of the founding members of the Brigham Health Care System, developed a FIND-seq that combines nucleic acid cytometry, microfluidics, and droplet classification to isolate and analyze rare cells of interest based on the expression of mRNA biomarkers detected by digital droplet PCR.
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Breakthrough testing for Alzheimer's disease: selective neurodegenerative blood biomarkers
Time of Update: 2023-02-03
References:Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration Neuroscientists have developed a groundbreaking test that can detect unique markers of neurodegeneration in Alzheimer's disease in blood samples.
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Nature Cancer reveals how chronic blood cancers transform into aggressive diseases
Time of Update: 2023-02-03
" ”DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression A study by Washington University School of Medicine in St. Louis suggests a strategy to prevent chronic, slow-growing blood cancers from progressing to aggressive leukemia.
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Nature: Mapping the transcriptome from primate embryonic gastrul motility to early organ development
Time of Update: 2023-02-03
Brightfield diagram of cynomolgus monkey embryos at CS8-CS11 (left) and 38 major cell taxa (right) Human life begins when the sperm fuses with the egg to form a fertilized egg (day 0 of the embryonic stage; Embryonic day 0; E0), the fertilized egg undergoes cleavage to form a blastocyst, which is planted around E7 to further develop in the maternal uterus.
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Cong Yao's group collaborated to develop neutralizing antibodies against coxsackievirus A16 and reveal its molecular mechanism
Time of Update: 2023-02-03
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Nature Immunology: When cancer-fighting T cells are depleted, they may change sides
Time of Update: 2023-02-03
Image: Dr. Greg Delgoffe, associate professor of immunology at Pitt College of Medicine and director of the Center for Oncology Microenvironment at UPMC Hillman Cancer CenterWhen T cells, the immune system's main anticancer agent, work overtime to fight tumors, they enter a state of exhaustion and no longer work properly.
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Groundbreaking study, the first evidence to show that serotonin deficiency is directly linked to depression
Time of Update: 2023-02-03
Lead author Dr David Erritzoe, MRCPsych, said: "This study used a new, more direct method to measure serotonin in living brains and showed that the release function of serotonin in depression is reduced.
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The secret of viral drug resistance hidden behind medical malpractice 40 years ago
Time of Update: 2023-02-03
The findings, recently published in the journal Cell Reports Medicine, have important implications for our understanding of viral resistance and the development of therapies to treat infected people.
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Studies have revealed that the prevalence of insomnia in patients with chronic schizophrenia is higher and related to cognitive impairment
Time of Update: 2023-02-03
The findings suggest that patients with chronic schizophrenia have a higher prevalence of insomnia compared to healthy people, and patients with insomnia have worse cognitive performance than those without insomnia.
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Guo Fan/Wang Hongmei's team analyzed the overview and regulation of DNA hydroxymethylation during early embryonic and germ cell development in mice
Time of Update: 2023-02-03
DNA methylation (5mC) has long been widely studied as the most classic DNA covalent modification in mammals, and it is essential for life processes such as gene expression regulation, transposon sile
