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MIT sets new targets for cancer vaccines
Time of Update: 2021-09-28
Researchers from the Massachusetts Institute of Technology (MIT) found that vaccination against certain cancer proteins can increase the overall T cell response in mice and help shrink tumors.
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The so-called "junk" DNA is essential and plays a key role in speciation
Time of Update: 2021-09-28
But when they investigated the importance of satellite DNA for the reproduction and survival of pure species, Yamashita and Jagannathan discovered for the first time clues that these repetitive sequences might play a role in speciation .
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A new method to identify the age of lobsters
Time of Update: 2021-09-28
Martin Taylor, head of the School of Biological Sciences at the University of East Ansia, said: “Up to now, the age of a lobster is usually estimated by its size, but this is inaccurate because the growth rate of individual lobsters is different .
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Phototherapy promotes Alzheimer's Aβ clearance
Time of Update: 2021-09-28
They explored the effect of 1070 nm pulsed 10Hz light on treatment of APP/PS1 mice .
"Our results prove the effects of 1070 nanometer light on microglia regulation and cerebral blood vessels at different stages of AD, and provide valuable insights into the mechanism of 1070 nanometer light treatment of AD .
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Break the barrier of the king of cancer!
Time of Update: 2021-09-28
The team from Johns Hopkins University re-examined pancreatic tumors from many aspects, which is expected to bring new targets for the diagnosis and treatment of pancreatic cancer .
Compared with normal pancreatic cells, the expression levels of 222 proteins in pancreatic cancer cells have increased by a factor of two.
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Proteins that cause Alzheimer's disease may come from outside the brain
Time of Update: 2021-09-28
Xinhua News Agency, Sydney, September 26 (Liu Shiyue) Australian researchers have discovered through animal experiments that the beta amyloid protein associated with Alzheimer's disease may come from other organs in the body and penetrate the brain through the blood .
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Two papers: the cause of an often overlooked genetic disease
Time of Update: 2021-09-28
Under the leadership of Sally Camper and Jacob Kitzman, professors of human genetics at the University of Michigan School of Medicine, several clinical endocrinologists and bioinformatics scientists have joined forces to further study splicing defects and their role in rare genetic hormonal diseases .
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Radiation therapy reprograms cardiomyocytes to a young state
Time of Update: 2021-09-28
However, this new study shows that non-invasive radiotherapy, commonly used to treat cancer, can reprogram heart muscle cells to make them younger and even healthier, solving the electrical problems of the cells themselves, without the need for scar tissue.
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Zhang Peng's research group collaborated to use dynamic network biomarker analysis to discover the molecular mechanism of sweet potato expansion
Time of Update: 2021-09-28
And regulation of sweet potato root tuberization" research paper, through dynamic network biomarker (DNB) analysis, reveals the key transcription factors and regulation mechanism in the process of sweet potato root enlargement .
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Common osteoporosis medications can reduce the risk of type 2 diabetes
Time of Update: 2021-09-28
A new study announced at the annual meeting of the European Association for the Study of Diabetes (EASD) showed that the widely used anti-osteoporosis drug alendronic acid can reduce the risk of type 2 diabetes .
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"Nature" special report: The virus closest to the new crown has been found in bats in Laos
Time of Update: 2021-09-28
Preprint at Research Square Coronaviruses with a SARS-CoV-2-like receptor binding domain allowing ACE2-mediated entry into human cells isolated from bats of Indochinese peninsula.
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Significantly relieve the symptoms of advanced DMD patients with phase 2 clinical results positive
Time of Update: 2021-09-28
On September 24, 2021, Capricor Therapeutics announced the final results of a phase 2 clinical trial of cell therapy CAP-1002 for the treatment of patients with advanced Duchenne muscular dystrophy (DMD) .
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A wide head helps sperm to swim together
Time of Update: 2021-09-28
"In order to carry out the automated measurement and machine learning aspects of this research, Fisher and Hook collaborated with Professor Wolfgang Losert of the Department of Physics and Institute of Physical Science and Technology of the University of Michigan and members of his laboratory .
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How to save hair loss?
Time of Update: 2021-09-28
In a recent article published in the journal Nature, a team of researchers at Tokyo Medical and Dental University (TMDU) used mouse model experiments to study how high-fat diets or gene-induced obesity affect hair thinning and loss .
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Nature Sub-Journal: Artificial Intelligence Reveals "Important Genes" in Agriculture and Medicine
Time of Update: 2021-09-28
Image source: New York University Cruze Lab"Our research shows that focusing on genes that are evolutionarily conserved across species expression patterns can improve our ability to learn and predict the'important genes' of major crop growth performance and animal disease outcomes," New York University Department of Biology and Genomics and Systems Professor Carroll and Milton Petrie of the Center for Biology, who are also the senior authors of the paper, explained .
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New imaging methods for gastric lymphoma
Time of Update: 2021-09-28
The research team at MedUni Vienna centered around Marius Mayerh?fer (Department of Biomedical Imaging and Image Guided Therapy), Markus Raderer (Department of Medicine I) and Alexander Haug (Department of Biomedical Imaging and Image Guided Therapy), the Department of Nuclear Medicine) now research A new imaging technique as an alternative to these repeated tissue extractions: Positron emission tomography combined with magnetic resonance imaging (PET/MR), using [68Ga]Pentixafor, a cell receptor CXCR4 (PET-tracer) A new type of radiolabeled molecule .
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GABA receptor allosteric modulator receives priority review qualification, significantly reduces seizure frequency
Time of Update: 2021-09-28
S. FDA has granted its GABAA receptor positive sex structure modulator ganaxolone a new drug application (NDA) priority review to treat epileptic seizures related to CDKL5 deficiency (CDD) .
Reference materials:[1] Marinus Pharmaceuticals Announces FDA Acceptance for Filing and Priority Review of New Drug Application for Ganaxolone in CDKL5 Deficiency Disorder.
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Gene therapy is up again!
Time of Update: 2021-09-28
In the higher dose group, 60% of subjects with rare eye diseases experienced unexpected serious adverse reactions (SUSARs) after receiving the company's gene therapy treatment .
As adverse events are limited to children receiving the highest dose, AGTC said it will continue to advance the development of this therapy .
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PNAS: guide microorganisms along their path
Time of Update: 2021-09-28
Observing its movement patterns, the Marco Mazza (Loughborough University and MPIDS) research team created a model to predict the probability of flow in a certain direction .
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The Jurassic scene reappeared?
Time of Update: 2021-09-28
A team of scientists from the Institute of Vertebrate Paleontology and Paleoanthropology of the Chinese Academy of Sciences (IVPP) and Shandong Tianyu Museum of Nature (STM) isolated well-preserved cartilage cells from a 125 million-year-old dinosaur in northeastern China.
