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Chinese scholars and overseas collaborators have made progress in the field of consumer behavior research
Time of Update: 2021-09-29
Figure 1 The loneliness score of numbers 1-100 (the larger the score, the higher the loneliness) With funding from the National Natural Science Foundation of China (approval number: 71872114, 71922018), Associate Professor Yan Dengfeng of New York University Shanghai and overseas collaborators explored how digital information affects consumer perceptions and preferences.
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Researchers establish a new prediction algorithm for prophage de novo
Time of Update: 2021-09-29
The team of Wang Xiaoxue, a researcher at the South China Sea Institute of Oceanology, Chinese Academy of Sciences, has established a new algorithm for prediction of prophage de novo that does not rely on the similarity of phage gene sequence .
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Phase III clinical success of Astellas NK3R antagonist fezolinetant in the treatment of menopausal VMS
Time of Update: 2021-09-29
The results from the SKYLIGHT 2 study showed that the 30mg and 45mg doses of fezolinetant orally once a day reached the common primary endpoint of the study: compared with placebo, the incidence and severity of moderate to severe VMS in weeks 4 and 12 were statistically significant Significantly reduced .
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LYBio's TCR-T therapy IND application was approved by the U.S. FDA for hepatocellular carcinoma
Time of Update: 2021-09-29
Text|Pharmaceutical Mission HillsOn September 23, Lion TCR Pte Ltd announced that the US FDA has approved its LioCyx-M004 New Drug (IND) application to start a phase 1b/2 international multi-center clinical trial (clinical trial name: LIBERO) , Used to treat primary hepatitis B virus (HBV)-related advanced hepatocellular carcinoma (HCC) .
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From α to Epsilon: Which is the more effective SARS-CoV-2 spike protein Spike antibody?
Time of Update: 2021-09-29
In fact, the researchers discovered three different sets of antibodies that can resist mutations in the SARS-CoV-2 spike protein .
Through this new research, CoVIC is one step closer to the development of more effective antibody therapies, which may protect against SARS-CoV-2 mutations .
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Nature sub-issue reports the structural mechanism of the activation of nitric oxide receptor sGC by stimulators and activators
Time of Update: 2021-09-29
On September 17, Chen Lei's research group at the Institute of Molecular Medicine, School of Future Technology, Peking University analyzed the high-resolution structure of the human-derived sGC full-length protein, YC-1 and riociguat, and the activator cinaciguat complex.
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The skin can also "listen"!
Time of Update: 2021-09-29
Although the hearing of nematodes has some similarities with the auditory system of vertebrates, this new study reveals important differences from the perception of sounds by vertebrates or arthropods .
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Synaptic dysfunction in schizophrenia: is it a loss of excitement or a loss of inhibition?
Time of Update: 2021-09-29
For a long time, researchers have suspected that the symptoms of schizophrenia originate from the interruption of synaptic function, or the abnormal way in which neurons communicate with each other, which may lead to an imbalance between excitatory and inhibitory transmission .
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What is the effect of wolfberry puree? Why can it be sought after in the health circle?
Time of Update: 2021-09-29
What are the effects of wolfberry puree?Nourish the liver and soothe the nervesThe pressure of modern people is very high.
Long-term persistence can not only improve the quality of sleep, but also nourish the liver and kidney, and have the effect of nourishing the liver and soothing the nerves .
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For millions of years, some animals have only females, they can reproduce purely asexually
Time of Update: 2021-09-29
Professor Tanja Schwander from the Department of Ecology and Evolution at the University of Lausanne explained that the Meselson effect describes the discovery of these differences in the genomes of pure asexual species .
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Nat. Chem. Biol. Back-to-back Shanghai Pharmaceuticals reveals the molecular mechanism of cholecystokinin receptor recognition ligand and G protein selectivity
Time of Update: 2021-09-29
In the second study, Qiang / Wubei Li / Mingwei / Yang Dehua / Zhao Suwen resolved joint team of CCK A R & lt small molecule antagonists Devazepide, three crystal structure Lintitript agonists and NN9056 binding, and the binding polypeptide Gastrin of CCK B R & lt The cryo-EM structure of two complexes coupled with G i and G q respectively (Figure 2a-e) .
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Pennsylvania mRNA scientists Drew Weissman and Katalin Karikó receive the 2021 Lasker Award, the highest biomedical research award in the United States
Time of Update: 2021-09-29
We found the best people in the world and asked them,'Do you want to collaborate on this vaccine?'" Image source: Penn Medicine (click on any image to get a full-size, high-resolution version)Karikó is also collaborating with fellow scientists on new discoveries, comparing the research to the excitement of watching a complex detective story unfold .
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Anti-artemisinin malaria in Africa: gain a foothold
Time of Update: 2021-09-29
At present, there is no evidence that current treatment methods are completely failing;Patients with drug-resistant parasites only need longer time to get rid of them .
Two recent studies have shown that these mutations are slowing the rate at which drug treatments remove parasites from patients .
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Sub-Journal of "Science": Infection with the new crown "old" virus is not enough to completely prevent new variants!
Time of Update: 2021-09-29
Some epidemiological reports point out that with the emergence of new variants of the new coronavirus, more and more cases of individuals who have been infected with the new coronavirus are re-infecte
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Nature publication: How the transcription factor KLF4 affects gene expression
Time of Update: 2021-09-28
A research team led by Baylor College of Medicine recently reported a new mechanism through which the transcription factor KLF4 can help form chromatin, thereby affecting gene expression .
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A new tool improves the accuracy of breast cancer detection
Time of Update: 2021-09-28
Image: Farah Shamout, Assistant Professor of Computer Engineering at New York University Ultrasound is still an important tool for screening, detecting and identifying breast cancer, usually combined with mammography .
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JAMA: There are two forms of metastatic prostate cancer, which can guide treatment
Time of Update: 2021-09-28
Based on the early detection of clinically relevant subtypes of breast cancer and non-metastatic prostate cancer, the researchers determined the genetic characteristics that can divide metastatic prostate cancer into two types: intraluminal and basal .
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Associate Professor Guo Shuai of the School of Mathematical Sciences has made important progress in the BCOV conjecture
Time of Update: 2021-09-28
9" >Recently, Associate Professor Guo Shuai from the School of Mathematical Sciences of Peking University and his collaborators have made important breakthroughs in the A-model structure of BCOV theory .
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Alzheimer's disease treatment can be expected in the future
Time of Update: 2021-09-28
Amyloid plaques in the brain are one of the goals of Alzheimer’s disease treatment[2]Almost the entire army was wiped out, and the FDA smashed its "golden sign"!Almost the entire army was wiped out, and the FDA smashed its "golden sign"!Nearly 20 years before 2021, the field of new drug research and development for neurodegenerative diseases was almost wiped out.
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A common genetic variation of mitochondrial RNA processing enzymes can easily lead to insulin resistance
Time of Update: 2021-09-28
The researchers used CRISPR-Cas9 genome editing to introduce the rs11156878 mutation in the Mrpp3 gene of mice, confirming that the mutation desensitized pancreatic β-cells by disrupting insulin secretion in high-fat diet (HFD).
