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A new imaging technique for detecting MALT malignant tumors of the lymphatic system may save patients from multiple gastroscopy
The stomach is a common origin of lymphoid carcinoma (lymphoma)
The research team at MedUni Vienna centered around Marius Mayerh?fer (Department of Biomedical Imaging and Image Guided Therapy), Markus Raderer (Department of Medicine I) and Alexander Haug (Department of Biomedical Imaging and Image Guided Therapy), the Department of Nuclear Medicine) now research A new imaging technique as an alternative to these repeated tissue extractions: Positron emission tomography combined with magnetic resonance imaging (PET/MR), using [68Ga]Pentixafor, a cell receptor CXCR4 (PET-tracer) A new type of radiolabeled molecule
The results show that [68Ga]Pentixafor PET/MR has high accuracy
"If a sufficiently high chemokine receptor CXCR4 expression is detected for early diagnosis of malt lymphoma, new imaging techniques can replace the disease during repeated gastroscopy and at least increase the time interval between gastroscopy in the future," said the first author of the study.
The research results support an earlier article published by the research team (published in the top journal "Theranostics" in 2019), which pointed out that [68Ga]Pentixafor PET/MR is used to detect MALT lymphoma in various organs and tissues Aspect has high sensitivity
DOI: 10.