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Wuhan Institute of Virology Immunity issued a paper: Research and development of antiviral drugs targeting viral RNAi inhibitors
Time of Update: 2021-10-11
RNAi is a highly conserved post-transcriptional gene silencing mechanism in eukaryotes, and it is also a highly effective antiviral natural immune mechanism . When the virus infects the host cell,
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Chinese scholars have made progress in the formation mechanism of natural hydrogen
Time of Update: 2021-10-11
Figure 1 Ni 2+ promotes Fe(OH) 2 oxidation to produce hydrogen and its mechanism schematic diagram Supported by the National Natural Science Foundation of China (Project Approval Number:
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The COVID-19 virus ravages the new crown vaccine research and development over the years at a glance
Time of Update: 2021-10-11
In addition, CanSino’s inhaled recombinant new coronavirus vaccine (adenovirus vector) is applying for emergency use authorization from the State Food and Drug Administration; the Institute of Microbiology, Chinese Academy of Sciences and Zhifei Biological are promoting the research and development of the second-generation recombinant vaccine; Accelerate the development of an mRNA nucleic acid vaccine .
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Youchao Beichun - TAA Tongen Medical's first domestic functional medicine concept product launched
Time of Update: 2021-10-11
Functional medicine, with its strong advantages in the field of chronic disease prevention and health management, has gradually played an increasingly important role in helping the "Healthy China 2030" strategy .
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The two-pronged approach of promoting whiteness and anti-tumor, Hengrui's license-in drug prenabulin has achieved another major breakthrough
Time of Update: 2021-10-11
Shanghai, September 24, 2021/PRNewswire/ - Recently, at the 2021 European Society of Medical Oncology (ESMO) annual meeting, the national original innovative drug punabulin announced its effectiveness
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eNeuro: withdrawal from psychostimulants will rebuild the functional structure of the brain
Time of Update: 2021-10-11
"We found that cocaine, methamphetamine, and nicotine withdrawal symptoms produced a major reshuffle of the brain area with an increase in the main functional connectivity in the whole brain control (saline) mice compared to," George said, "with a decrease in modular structure The strongest of the brain is methamphetamine, cocaine, and nicotine .
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BioVaxys initiates groundbreaking research
Time of Update: 2021-10-11
(CSE: BIOV) (FRA: 5LB) (OTCQB: BVAXF) (hereinafter referred to as "BioVaxys" or "Company") announced today , The company initiated a scientifically groundbreaking study on the reduced binding ability of the hapten-modified spike protein ACE2, which is the basis of the company’s new coronavirus SARS-CoV-2 vaccine BVX-0320 .
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Withdrawal drugs (nicotine, etc.) will reshape the brain communication network
Time of Update: 2021-10-11
For these three drugs, compared with the control group, the brain in the abstinent state showed greater functional connectivity—a method of measuring synchronized activity and communication between brain regions .
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Nucleic Acids Research releases new version of plant microRNA database
Time of Update: 2021-10-11
0 released this time covers a variety of data related to 39,751 miRNAs in 179 plants, and the database function has been upgraded from the following five aspects: 1) 91 species of microRNAs, target genes and related information have been added; 2 ) Provide 8 tools for microRNA related information mining; 3) Provide 3 tools for microRNA molecular genetic experiment design; 4) Build a plant microRNA information exchange and sharing platform; 5) UI and website security upgrades (Figure 1) .
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PNAS introduces vaccination without injection: 3D printed vaccine patch
Time of Update: 2021-10-11
Scientists at the University of North Carolina at Chapel Hill and Stanford University use 3D printers to produce microneedle vaccine patches, which can dissolve in the skin and improve immunity .
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FDA approves the treatment of infants over 1 month of age with better epilepsy therapy to expand the patient group
Time of Update: 2021-10-11
S. FDA has approved its Briviact (brivaracetam) to expand its adaptation to the patient group for the treatment of partial-onset seizure (POS) in pediatric patients over one month old.
Retrieved August 30, 2021, from https:// releases/ucb-announces-briviact-brivaracetam-cv-now-fda-approved-to-treat-partial-onset-seizures-in-pediatric-patients-one-month-of-age-and-older-301364625.
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Research and innovation breakthroughs may open up new worlds of RNA editing
Time of Update: 2021-10-11
The researchers loaded the CRISPR RNA required by the REPAIR system together with Cas13bt1 into the AAV2 vector, confirming that it can edit human cell lines .
1038/s41587-021- 01030-2[2] Feng Zhang's lab develops potential breakthrough in RNA editing delivery using'ultracompact' versions of Cas13, Retrieved August 30, 2021, from https://endpts.
com/feng-zhangs-lab-develops-potential-breakthrough-in- rna-editing-delivery-with-ultracompact-versions-of-cas13/
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The new "battle" of cell and gene therapy: how to break through the technological bottleneck?
Time of Update: 2021-10-11
"In response to industry needs, Cytiva has established a research and development and production platform for viral vectors with different serotypes, from cell culture to transfection and downstream purification, to help gene therapy companies promote process development and scale-up production as soon as possible," said Yang Hongyan To .
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Targeted editing, inhibition, and degradation of mRNA ADARx Pharmaceuticals receives US$7,500 in assistance
Time of Update: 2021-10-11
The funds from this round of financing will be used to advance ADARx's technology platform for targeting mRNA, including editing, inhibiting or degrading mRNA, and tissue-specific delivery technologies .
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Today's "Nature": Chinese team to inhibit tumor growth makes new discoveries
Time of Update: 2021-10-11
They reintroduced the UTX protein with this disordered region into cancer cells lacking the UTX gene to restore their ability to form aggregates and promote "liquid-liquid separation" .
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Nat Commun: Giving two peptides through the nose is expected to slow the progression of Parkinson's disease
Time of Update: 2021-10-11
The relevant research results were published in the journal Nature Communications on September 10, 2021, with the title of the paper "Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo" .
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The catalog of medical devices exempt from clinical evaluation, and the catalog of in vitro diagnostic reagents exempt from clinical trials are released
Time of Update: 2021-10-11
On September 18, in order to do a good job in the registration and management of medical devices, in accordance with the relevant registration and filing management measures, the State Food and Drug Administration organized and formulated the catalog of medical devices exempt from clinical evaluation and the catalog of in vitro diagnostic reagents exempt from clinical trials.
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Innovative liquid biopsy with only one urine sample is more than 90% accurate in predicting prostate cancer
Time of Update: 2021-10-11
Image source: miR Scientific's official websiteWhen comparing the results of miR Sentinel detection technology with systematic needle biopsy among men who were initially suspected of prostate cancer, the study showed that the consistency of the two screening and detection methods in the classification of clinically significant cancer was 93% .
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First in class selective SIRPα inhibitor phase I results are positive
Time of Update: 2021-10-11
Article source: Medical Rubik's Cube InfoAuthor: Shi BeiOn September 16, OSE and Boehringer Ingelheim (BI) jointly announced the first-in-class selective SIRPα inhibitor BI 765063 combined with PD-1 monoclonal antibody BI 754091 (ezabenlimab) to treat patients with advanced solid tumors in phase I dose escalation positive data .
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Chu Chengcai's research team collaborated to discover a cytokinin signaling pathway hidden in the brassinolide signaling component to regulate rice grain size
Time of Update: 2021-10-11
The classical cytokinin signal transduction depends on the histidine receptor kinase HK , histidine phosphotransferase HP , and the histidine (H) and aspartic acid (D) in the cytokinin response facto
