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Where did the cat pattern come from?
Time of Update: 2021-10-11
Determined by differences in embryonic gene expression Determined by differences in embryonic gene expressionScience and Technology Daily, Beijing, September 7 (Reporter Zhang Mengran) A genetic study published on the 7th in the British journal Nature Communications pointed out that the formation of fur patterns (such as stripes) on domestic cats is determined by specific molecules in the developing embryo.
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Research found that a cytokinin signaling pathway regulates rice grain size
Time of Update: 2021-10-11
The PPKL1-D364 mutation loses its inhibitory function on the phosphate relay, but because the mutant protein still occupies the position of interaction with AHP2, it constitutively activates the cytokinin signal through a dominant negative regulatory mechanism, resulting in a significant increase in grains .
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Bojian Vumerity is recommended by EU CHMP for the treatment of multiple sclerosis
Time of Update: 2021-10-11
CompilationTom LeeA few days ago, the European Commission for Medicinal Products for Human Use (CHMP) announced the recommendation of Bojian Vumerity (diroximelfumarate) for the treatment of patients with relapsing-remitting multiple sclerosis (RRMS) .
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Eli Lilly's $1.6 billion layout opens up a new world of targeted therapy, do you know these new developments?
Time of Update: 2021-10-11
This technology couples antibodies or small molecules that target extracellular proteins with oligoglycopeptides that can bind to the CI-M6PR receptor expressed on the cell surface .
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Polyplastics uses new detection methods to detect and prevent gas combustion during injection molding
Time of Update: 2021-10-11
, the world's leading supplier of engineering thermoplastics, has discovered a variety of solutions that can effectively help processors reduce injection molding Gas combustion phenomenon that occurs in the process .
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The brain is a predictive machine-and music reveals how it works
Time of Update: 2021-10-11
Hansen proved that research participants experienced so-called musical phrases—corresponding to a sentence or "unit of meaning"—as complete and summarized, like a phrase ending in an indeterminate tone, not knowing what will happen next What .
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Cell: Zhang Chunli's research team reveals that strict lineage tracing is critical to the study of nerve cell regeneration
Time of Update: 2021-10-11
At the end of the study, reliable pedigree tracing tests are listed, and it is strongly recommended that these tests be used in all laboratories engaged in nerve cell regeneration research .
Zhang's laboratory has reported some advances in neural stem cell biology, such as the regeneration of mouse brain and spinal cord after injury .
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"Cell": Enhancing the Potential of CAR-T Therapy in Treating Solid Tumors Carl June's Team Makes New Move
Time of Update: 2021-10-11
Our research shows that given the right "weapons", they can activate the body's own immune system and help them fight tumor cells .
html[2] Johnson et al, (2021) The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function, Cell, DOI: 10.
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FDA approves new nasal spray therapy for migraine relief within 15 minutes
Time of Update: 2021-10-11
S. FDA approved Dihydroergotamine mesylate (DHE) nasal spray Trudhesa (formerly known as INP104) for the acute treatment of adult migraine (with or without aura) .
"Reference materials:[1] Impel NeuroPharma Announces US FDA Approval of Trudhesa™ (Dihydroergotamine Mesylate) Nasal Spray for the Acute Treatment of Migraine.
Retrieved September 3, 2021, from https:// 03/2291459/0/en/Impel-NeuroPharma-Announces-US-FDA-Approval-of-Trudhesa-Dihydroergotamine-Mesylate-Nasal-Spray-for-the-Acute-Treatment-of-Migraine.
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The international community should carry out traceability of the new coronavirus in many countries and places
Time of Update: 2021-10-11
For example, a retrospective survey study in The Lancet on January 24, 2020 showed that among the first batch of 41 cases of new coronary pneumonia confirmed by laboratories in Wuhan from December 16, 2019 to January 2, 2020 , The earliest case of symptoms can be traced back to December 1, 2019, and the patient has no history of exposure to the South China Seafood Market .
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Cinda Biotech and Baoyuan Pharmaceutical announce the interim data of the phase II trial of Taletrectinib in ROS1-positive non-small cell lung cancer at the CSCO annual meeting in 2021
Time of Update: 2021-10-11
("Baoyuan Pharmaceutical"), a company dedicated to the development of new types of first-in-class or best-in-class The clinical stage company of precision tumor therapy jointly announced today the interim data of the second phase trial of a new generation of ROS1/NTRK inhibitor Taletrectinib for ROS1-positive non-small cell lung cancer .
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Guangzhou Health Institute research confirms that there is a new cure for multi-drug-resistant tuberculosis
Time of Update: 2021-10-11
Zhang Tianyu, State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences & Guangdong-Hong Kong-Macao Respiratory System Infectious D
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Kangfang Bio-Kaidening PD-1/CTLA-4 dual antibody treatment of cervical cancer marketing application accepted
Time of Update: 2021-10-11
Professor Wu Xiaohua, director of the Department of Oncology and Gynecology of the Cancer Hospital of Fudan University, said that although PD-1 monoclonal antibody for the treatment of cervical cancer has been approved for marketing worldwide, clinical research results show that it is only in PD-L1 positive patients above the second line.
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Targeted editing, inhibition, and degradation of mRNA ADARx Pharmaceuticals receives US$7,500 in assistance
Time of Update: 2021-10-11
The funds from this round of financing will be used to advance ADARx's technology platform for targeting mRNA, including editing, inhibiting or degrading mRNA, and tissue-specific delivery technologies .
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Inspur Storage Hu Wenfeng: Inspur becomes a mainstream player of enterprise SSD
Time of Update: 2021-10-11
Hu Wenfeng, General Manager of SSD Products, Inspur Storage Product LineMagnetic retreat silicon into SSD to carry a new type of data centerWith the continuous emergence of new technologies such as big data, artificial intelligence, and the Internet of Things, the rapid development of the digital economy has driven the data center market to usher in new changes .
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BioVaxys initiates groundbreaking research
Time of Update: 2021-10-11
(CSE: BIOV) (FRA: 5LB) (OTCQB: BVAXF) (hereinafter referred to as "BioVaxys" or "Company") announced today , The company initiated a scientifically groundbreaking study on the reduced binding ability of the hapten-modified spike protein ACE2, which is the basis of the company’s new coronavirus SARS-CoV-2 vaccine BVX-0320 .
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Withdrawal drugs (nicotine, etc.) will reshape the brain communication network
Time of Update: 2021-10-11
For these three drugs, compared with the control group, the brain in the abstinent state showed greater functional connectivity—a method of measuring synchronized activity and communication between brain regions .
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Research and innovation breakthroughs may open up new worlds of RNA editing
Time of Update: 2021-10-11
The researchers loaded the CRISPR RNA required by the REPAIR system together with Cas13bt1 into the AAV2 vector, confirming that it can edit human cell lines .
1038/s41587-021- 01030-2[2] Feng Zhang's lab develops potential breakthrough in RNA editing delivery using'ultracompact' versions of Cas13, Retrieved August 30, 2021, from https://endpts.
com/feng-zhangs-lab-develops-potential-breakthrough-in- rna-editing-delivery-with-ultracompact-versions-of-cas13/
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My husband entered the ICU due to the new crown, but I am safe and may never be infected
Time of Update: 2021-10-11
The genetic level of immunized patients shows the opposite trend-due to some mutations, the expression of key genes in their bodies will be different, making NK cells more active, which may help them resist the new coronavirus infection .
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New anti-cancer mRNA therapy: more than 80% of mouse tumors have completely disappeared, and the efficacy of PD-1 antibody is improved
Time of Update: 2021-10-11
Article source: Medical Rubik's Cube ProAuthor: Li YuanmRNA therapy was first used in tumor treatment, by injecting mRNA encoding cytokines and other specific proteins into the tumor to activate the immune response .
Source: Science Translational MedicineIn addition, the combination of mRNA mixture and PD-1 inhibitor can further enhance its anti-tumor effect .
