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The response of the gut-brain axis to inflammation may be the basis of inflammatory bowel disease-related psychiatric symptoms
Time of Update: 2021-11-02
Although this dysregulation of the intestinal cerebrovascular axis may protect the brain from inflammation, research results indicate that it may also cause various cognitive and psychiatric symptoms associated with IBD .
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Targeting cancer on the nanoscale
Time of Update: 2021-11-02
The first author Hiroki Kato explained: “We have developed a new safe and powerful cancer treatment method using gold nanoparticles containing astatine-211, which can emit alpha rays that strongly damage the target DNA.
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Bacteria’s mobile genetic elements drive bacterial resistance to bacteriophages
Time of Update: 2021-11-02
These bacteriophage defense elements show extremely rapid evolutionary transformation, leading to differences in bacteriophage susceptibility between bacterial strains, while the phage receptors on the surface of the bacteria remain unchanged.
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2021 Peking University Medical Autism International Forum Successfully Held
Time of Update: 2021-11-02
10 Yue 16 - The 17 May 2021 Nian PUHSC autism International Forum (social behavior and autism) at the Peking University Lui Che Woo floor B101 success of the conference room . Autism is an annual in
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October 22, 2021: He Xiangwei's laboratory published a long article in PNAS revealing unstable genetic traits and genome diversity mediated by reversible genetic mutations
Time of Update: 2021-11-02
This work provides direct experimental evidence for the hypothesis that "single-copy to two-copy MTD mutations may be the origin of multiple copies of tandem repeats that already exist in the genome" (see references); at the same time, it reveals the hidden hidden in the cell population.
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The latest achievements of the teams of Fudan University Ding Chen and He Fuchu have developed a "toolkit" for precise analysis of protein-DNA transcription machinery in the open region of chromatin
Time of Update: 2021-11-02
Beijing 2021 Nian 10 Yue 23 days, "Science" ( Science ) magazine child journal "Science Progress" ( Science in Advances ), published online the State Key Laboratory of Genetic Engineering, Fudan Univ
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Boehringer Ingelheim and partners accelerate development of first-of-its-kind gene therapy for cystic fibrosis patients
Time of Update: 2021-11-02
Building on the tremendous progress made so far, we are very happy about the world's leading respiratory disease One of the pharmaceutical companies, Boehringer Ingelheim, chose to exercise the option to license OXB lentiviral vector manufacturing technology to produce this highly innovative formula for inhaled cystic fibrosis gene therapy developed by GTC .
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This god assists and helps checkpoint inhibitors to awaken the immune system of cancer
Time of Update: 2021-11-02
Michael Yaffe, director of the MIT Cancer Precision Medicine Center, said: "When you make cells with DNA damage but not killed, under certain conditions, these surviving and damaged cells will send a signal to Wake up the immune system .
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The first diabetic patient successfully regenerated insulin after receiving stem cell injections
Time of Update: 2021-11-02
Before treatment (left) and after treatment (right) of Elizabeth Hughes, the world's first diabetic patient receiving insulin treatment However, for patients with type 1 diabetes, it can only be maintained by insulin therapy, which leads to the fundamental problem of the disease-pancreatic islet cells cannot produce insulin by themselves, and there is no other way to solve it .
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Scientists use "time machine" made by human cells to reverse the progression of pancreatic cancer
Time of Update: 2021-11-02
Bumsoo Han, professor of mechanical engineering at Purdue University and project leader of Purdue University Cancer Research Center, said: "These discoveries open up the possibility of designing a new gene therapy or drug, because now we can convert cancer cells back to their normal state.
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Analysis of circular RNA transcriptome in medulloblastoma under the condition of Hedgehog signal activation
Time of Update: 2021-11-02
Hedgehog signaling plays an important role in normal development and homeostasis, and its continuous activation is associated with the initiation and growth of a variety of tumors-including basal cell carcinoma, medulloblastoma, rhabdomyosarcoma, breast cancer, colon cancer, and pancreatic cancer And lung cancer .
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Peking University's Blood published an article: The molecular mechanism of skin T-cell lymphoma large cell transformation and new therapeutic targets
Time of Update: 2021-11-02
Therefore, in-depth study of the key molecular regulatory mechanisms of skin T-cell lymphoma LCT has important clinical significance for finding potential therapeutic targets, delaying disease progression, and improving patient prognosis .
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Peking University Bai Fan’s teamwork results: Liquid-liquid separation and membraneless liquid protein aggregates analysis in bacteria
Time of Update: 2021-11-02
It was confirmed by time-resolved microscopy that aggresomes are membraneless droplets with a diameter of hundreds of nanometers, and the phase separation occurs after the aggregation of diffusion proteins under the thermal equilibrium in the bacterial cytoplasm .
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Genomic research reveals hereditary retinal diseases in different populations
Time of Update: 2021-11-02
An international research team, scientists from the University of California, San Diego, and the Shiley Institute of Ophthalmology, University of California, San Diego, led the study to expand and deepen the understanding of how inherited retinal dystrophy (IRD) affects different populations, in the process , Discovered new gene mutations that may cause disease .
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Science new mechanism of muscle regeneration
Time of Update: 2021-11-02
The lead author of the study, iMM and UPF researcher William Roman explained: "Even under physiological conditions, regeneration is essential for muscles to withstand the mechanical stress of contraction, which often leads to cell damage .
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Bacteria and fungi interact more frequently than previously thought
Time of Update: 2021-11-02
"This research contributes to a new understanding of the fungal flora, that is, the presence of bacteria in and closely related to the fungal host, in order to more closely study the interaction and link the research to issues such as ecosystem functions and the impact of climate change.
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A low-cost portable device can diagnose a heart attack in minutes
Time of Update: 2021-11-02
"The current methods used to diagnose a heart attack are not only time-consuming, but must be applied within a certain period of time to get accurate results," said Pinar Zolu, a professor at Notre Dame’s Sheen Family School of Engineering and the lead author of the paper.
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Reversing aging, changing DNA methylation for 2 months can make people 3 years younger!
Time of Update: 2021-11-02
Recently, researchers from the American Society for Functional Medicine, University of California, Los Angeles and other institutions published an article entitled "Epigenetic age may be reversed through diet and life> .
This study is the first randomized controlled clinical trial to prove that diet and life> .
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The Wang Jian research group of the School of Physics and collaborators observed the parallel field quantum Griffith singularity in a two-dimensional crystalline superconductor
Time of Update: 2021-11-02
9" >Professor Wang Jian’s research group and collaborators from the Center for Quantum Materials Science, School of Physics, Peking University have recently observed quantum Griffiths under a parallel magnetic field in a high-quality crystalline palladium ditelluride (PdTe 2 ) superconducting film grown by molecular beam epitaxy.
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Cancer Cell: Many patients with double vaccinations have poor immune response
Time of Update: 2021-11-02
The author believes that in the absence of the protection usually provided by vaccines, this study shows the importance of continuing to take public health measures to limit the spread of SARS-CoV-2, and the urgency of strengthening the plan, especially in the United Kingdom delta type When the virus spreads highlyPatients with solid cancers, such as breast cancer, urology, or skin cancer, also respond poorly to a single dose of the vaccine, with a seroconversion rate of only 38% .
