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The research team conducted a breakthrough clinical trial
DNA methylation is a chemical modification of DNA, which can change genetic properties without changing the DNA sequence
Many species, including humans, undergo DNA methylation as they age
In 2013, Steve Horvath, a professor of human genetics and biostatistics at the University of California, Los Angeles, united more than 100 laboratories to analyze the blood and blood of more than 200 mammals.
In this randomized controlled clinical trial, the research team conducted experiments on more than 40 healthy male volunteers between the ages of 50-72
Specific guidance plan:
Diet plan:
In the diet plan, participants were asked to fast intermittently (no food between 7pm and 7am), limit calorie intake, and focus on plant-based diets, including green leafy vegetables, cruciferous vegetables, and low-sugar fruits, and A small amount of eggs and meat (as organic as possible, free of hormones and antibiotics), try to avoid sugary foods and drinks, and supplement with probiotics every day
Exercise plan:
At least 5 days a week, exercise for more than 30 minutes a day, the exercise intensity is 60-80% of the maximum self-fatigue
Sleep plan:
Get at least 7 hours of sleep every night
Relaxation plan:
The relaxation method developed by Dr.
After the eight-week experiment was over, the researchers collected saliva samples from the participants for genome-wide DNA methylation analysis, and used the epigenetic clock developed by Professor Steve Horvath to calculate and found that compared with the control group, it was 8 weeks Their diet, exercise, sleep and relaxation therapy reduced their DNA methylation age by 3.
This study is the first randomized controlled clinical trial to prove that diet and life>
Finally, the leader of the study, Dr.
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