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A new mechanism involved in regulating myocardial elasticity
Time of Update: 2022-05-11
The study, published in Redox Biology, builds on earlier observations showing that oxidation of the amino acid cysteine modulates the in vitro mechanical properties of carnosine .
This group of conserved cysteines is observed to modulate the mechanical properties of carnosine in vitro .
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Scientists discover a new mechanism that regulates the elasticity of the heart muscle
Time of Update: 2022-05-11
The study, published in Redox Biology, builds on earlier observations showing that oxidation of the amino acid cysteine modulates the in vitro mechanical properties of carnosine .
This group of conserved cysteines is observed to modulate the mechanical properties of carnosine in vitro .
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China finds first human case of H3N8 bird flu infection
Time of Update: 2022-05-11
China's National Health Commission said Tuesday that a four-year-old boy living in central Henan province tested positive for the virus after being hospitalized with fever and other symptoms earlier this month .
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Gut microbiome may alter response to cancer treatment
Time of Update: 2022-05-10
"Overall, these findings support the possibility of reducing the side effects of conventional cancer treatments by affecting the gut microbiome," Shah said .
"There are still exciting possibilities to be explored, including the impact of healthy diets, probiotics, new treatments and more .
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Unraveling the origin of the human spine
Time of Update: 2022-05-10
Researchers from the Ebisuya Group at EMBL in Barcelona have now created a 3D in vitro model that mimics the precursor structures that give rise to spine forms during human embryonic development .
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Sleep deprivation damages stem cells in cornea, study shows
Time of Update: 2022-05-10
Studies have shown that chronic sleep deprivation can have serious effects on corneal health, such as thinning, wrinkling and reduced transparency of the cornea .
These data suggest that sleep deprivation negatively affects corneal stem cells, which may lead to vision impairment in the long term .
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Viruses Xu Ke's research group published a review on the research progress of broad-spectrum antiviral drugs
Time of Update: 2022-05-10
On April 28, 2022, Xu Ke's research group from the State Key Laboratory of Virology, Wuhan University published a paper entitled "A broad antiviral strategy: Inhibitors of human DHODH pave the way for
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Amino acid deficiency shrinks childhood tumors
Time of Update: 2022-05-10
a, Representative western blot of MYCN-knockdown IMR5/75 neuroblastoma cells using Dox (expression: ?Dox, high; + Doxorubicin, low); this experiment was repeated three times .
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The Sleep Mystery: The Molecular Centers That Regulate Deep Sleep
Time of Update: 2022-05-10
"We believe our findings lay the groundwork for the development of a new class of sleep drugs that can enhance the maintenance of deep sleep by enhancing delta wave oscillations," added Basheer, who with colleague Ritchie Brown Leading the study, he is an associate professor of psychiatry at HMS .
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Does the human brain really have "nerd cells"?
Time of Update: 2022-05-10
For example, I see the bus coming and I can feel the coffee is hot; what speed do I run to the bus so I don't burn myself?In recent years, the research community has demonstrated that the brain regions of interest to Boccara are involved in more tasks than spatial location mapping .
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Li Jixi's group discovered a highly effective prognostic marker for glioblastoma
Time of Update: 2022-05-10
Protein expression levels and prognostic analysis of different chemokines in glioblastoma samples Li Jixi's research group from the School of Life Sciences, Fudan University has long been engaged in the research on cell death and immune response .
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Cell: How to eat "longevity diet" to live longer
Time of Update: 2022-05-10
Science and Technology Daily, Beijing, April 28 (Reporter Zhang Mengran) In a review article published in the journal "Cell" on the 28th, Walter Langer, a professor at the Leonard Davis School of Gerontology at the University of Southern California, and co-authors at the University of Wisconsin Rozarin Anderson describes the "macrobiosis diet," a multi-pillar approach based on research on all aspects of the diet, from food composition to calorie intake .
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Viruses Xu Ke's research group published a review on the research progress of broad-spectrum antiviral drugs
Time of Update: 2022-05-10
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BGI Research Reveals the Mutual Orthogonal Molecular Mechanism of Novel PylRS/tRNAPyl
Time of Update: 2022-05-10
On April 25, 2022, a team from Shenzhen BGI Life Sciences Research Institute published online at Nucleic Acids Research (IF=17) entitled "The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNA Pyl pairs in the same organism”, which unearthed two novel PylRS/tRNA Pyl pairs that coexist in the halophilic methanogenic archaea Candidatus Methanohalarchaeum thermophilum HMET1 , using the model halophilic archaea H, which is closely related to HMET1.
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Molecular basis of deep sleep pinpointed, new treatments proposed
Time of Update: 2022-05-10
"We believe our findings lay the groundwork for the development of a new class of sleep drugs that can enhance the maintenance of deep sleep by enhancing delta wave oscillations," added Basheer, who with colleague Ritchie Brown Leading the study, he is an associate professor of psychiatry at HMS .
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Why this plant virus is so powerful in fighting cancer
Time of Update: 2022-05-10
2c00058 For the past seven years, researchers at UC San Diego and Dartmouth College have been studying and testing cowpea mosaic virus (in nanoparticle form) as a cancer immunotherapy, reporting in lab mice and pet dogs promising results .
"This study helps confirm cowpea mosaic virus nanoparticles as our lead candidate for cancer immunotherapy," Steinmetz said .
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Shanghai Jiaotong University Deng Zixin's team collaborated to reveal the biosynthetic mechanism of the super antibiotic darobactin
Time of Update: 2022-05-10
Recently, Professor Deng Zixin's team from the School of Life Science and Technology of Shanghai Jiao Tong University and the State Key Laboratory of Microbial Metabolism jointly published a research paper entitled "Radical SAM-dependent ether crosslink in daropeptide biosynthesis" in "Nature Communications", revealing the super antibiotic darobactin for the first time.
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Shanghai Jiaotong University Li Dan's group and collaborators discovered and characterized a novel pathological protein fiber aggregate formed by TMEM106B in the human brain
Time of Update: 2022-05-10
In this study, researchers discovered a previously unknown cluster of novel pathological proteins extracted directly from the brain tissue of a Parkinson's disease dementia (PDD) patient with dementia and two elderly healthy controls.
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Front. Neurosci.︱High-precision panorama of whole-brain Aβ plaques and surrounding structures in Alzheimer's disease model mice
Time of Update: 2022-05-10
On April 19, 2022, the MOST and Image Fusion Technology Service Department of Shanghai Institute of Materia Medica, Chinese Academy of Sciences published a research paper entitled "High-Resolution Digital Panorama of Multiple Structures in Whole Brain of Alzheimer's Disease Mice" in Frontiers in Neuroscience .
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Chinese scholar Nature sub-published article: Artificial synthesis of glucose and fatty acids from carbon dioxide
Time of Update: 2022-05-10
The artificial conversion of carbon dioxide into high value-added compounds, "turning waste into treasure", is an important area for continuous research in the scientific and technological circles .
