-
Nature sub-issue 1 published 2 articles: The new oncolytic virus is equipped with dual antibodies to treat glioma; Inventory of the "arming" strategy of multiple oncolytic viruses
Time of Update: 2023-01-06
Official website of each company——List of recent popular events——November 23, Key Elements of Quality Control for mRNA VaccinesNovember 19, 2022 / eMedClub News / -- November 17, 2022, Nature Cancer In an article titled "An armed oncolytic virus for GBM destruction," an oncolytic herpes simplex virus (oHSV) that carries a bispecific EGFR-CCL5 antibody fusion protein that activates innate and adaptive anti-tumor immune responses has shown extremely high efficacy in preclinical models of glioblastoma (GBM).
-
Nature sub-issue 1 published 2 articles: The new oncolytic virus is equipped with dual antibodies to treat glioma; Inventory of the "arming" strategy of multiple oncolytic viruses
Time of Update: 2023-01-06
Official website of each company——List of recent popular events——November 23, Key Elements of Quality Control for mRNA VaccinesNovember 19, 2022 / eMedClub News / -- November 17, 2022, Nature Cancer In an article titled "An armed oncolytic virus for GBM destruction," an oncolytic herpes simplex virus (oHSV) that carries a bispecific EGFR-CCL5 antibody fusion protein that activates innate and adaptive anti-tumor immune responses has shown extremely high efficacy in preclinical models of glioblastoma (GBM).
-
Expert Comment/Efgartigimod can coexist with the body defense of patients with generalized myasthenia gravis! ——2022 AANEM Essence Hot Review Series No. 2
Time of Update: 2023-01-06
Myasthenia gravis (MG) is an autoimmune disease mediated by immunoglobulin G (IgG) that continuously affects the life and health of patients and increases the burden on society1. Previous studies have
-
Expert Comment/Efgartigimod can coexist with the body defense of patients with generalized myasthenia gravis! ——2022 AANEM Essence Hot Review Series No. 2
Time of Update: 2023-01-06
Myasthenia gravis (MG) is an autoimmune disease mediated by immunoglobulin G (IgG) that continuously affects the life and health of patients and increases the burden on society1. Previous studies have
-
Neuron Liu Kai's team found that activating type II interferon and cGAS-STING signaling pathways in the nervous system can promote axon regeneration
Time of Update: 2023-01-06
On November 11, 2022, Liu Kai's research group of the Hong Kong University of Science and Technology published a long article "Driving Axon Regeneration by Orchestrating Neuronal and Non-neuronal Innate Immune Responses via the" in Neuron IFNγ-cGAS-STING Axis, found that by knocking out PTPN2 and adding type II interferon stimulated genes (ISGs) in neurons including the cGAS-STING pathway, it was possible to activate interferon stimulated genes (ISGs).
-
The Transl Psychiatry-Suiqiang Zhu/Zhou Zhu team revealed that structural disconnection due to stroke predicts the risk of depression after stroke
Time of Update: 2023-01-06
Written by Pan Chensheng, Zhu ZhouResponsible editor—Wang Sizhen, Fang YiyiEditor—Summer LeafPost-stroke depression (PSD) occurs in about one-third of stroke people, and is associated with poor post-s
-
Nature Communications: Inhibit neural circuits for undesirable motivational behavior, or reduce drug addiction
Time of Update: 2023-01-06
1038/s41467-022-34517-wThe images in the article are from referencesPVT excitatorycan also blockFigure 2: NAc region small albumin neurons mediate inhibitory reward behavior3Opioids dissociate their receptors and inhibit rewarding effectsIntraperitoneal injection of the opioid heroin significantly reduced the neuronal activity of PVT →NAc circuit.
-
Nature: Zhong Haining's team discovered the brain's "brake" mechanism for motor control, opening up a new avenue for Parkinson's disease treatment
Time of Update: 2023-01-06
On November 10, 2022, the team of Zhong Haining of the Vollum Institute of Oregon Health and Science University published a report in Nature entitled Locomotion activates PKA through dopamine and adenosine in striatal neurons Research papers.
-
Nature Medicine: Cognition is normal, but Aβ and Tau PET are both positive, and the risk of cognitive decline soars 18 times in the next 3-5 years!
Time of Update: 2023-01-06
The study found that the group with both Aβ and tau positive (A+T+) but cognitively normal after PET verification had a 19-fold increase in the risk of progressing to MCI within 3~5 years compared with the negative group (A-T-)++-[1]!
-
Neuron Mo Wei's team revealed that microglia sense amyloid plaque hardness through Piezo1 to limit the progression of Alzheimer's disease
Time of Update: 2023-01-06
Alzheimer's disease (AD) is the most common neurodegenerative disease in older adults and is characterized by progressive cognitive impairment and behavioral impairment. The two typical pathological f
-
Neuron Mo Wei's team revealed that microglia sense amyloid plaque hardness through Piezo1 to limit the progression of Alzheimer's disease
Time of Update: 2023-01-06
Alzheimer's disease (AD) is the most common neurodegenerative disease in older adults and is characterized by progressive cognitive impairment and behavioral impairment. The two typical pathological f
-
Research reveals the basis of neural circuits in the occurrence of psychiatric symptoms in Alzheimer's disease
Time of Update: 2023-01-06
On November 1, Li Jiali, a researcher at the Kunming Institute of Zoology, Chinese Academy of Sciences, published a research paper entitled Hyper-excitability of corticothalamic PT neurons in mPFC promotes irritability in the mouse model of Alzheimer's disease in Cell Reports 。 This paper uses a mouse disease model to analyze the neural circuit mechanism of irritability symptoms in Alzheimer's disease.
-
Research reveals the basis of neural circuits in the occurrence of psychiatric symptoms in Alzheimer's disease
Time of Update: 2023-01-06
On November 1, Li Jiali, a researcher at the Kunming Institute of Zoology, Chinese Academy of Sciences, published a research paper entitled Hyper-excitability of corticothalamic PT neurons in mPFC promotes irritability in the mouse model of Alzheimer's disease in Cell Reports 。 This paper uses a mouse disease model to analyze the neural circuit mechanism of irritability symptoms in Alzheimer's disease.
-
Microglia sense amyloid plaque hardness through Piezo1 to limit Alzheimer's disease progression Cell Press spoke to scientists
Time of Update: 2023-01-06
Life SciencesLife scienceRecently, Professor Mo Wei's team of Xiamen University published the research results entitled "Microglial Piezo1 senses Aβ fibrils stiffness to restrict Alzheimer's disease"
-
Nature allows paralyzed patients to regain the ability to walk
Time of Update: 2023-01-06
Written by | JunSpinal cord injury (SCI) interrupts the connection from the brain and brainstem to the lumbar spinal cord, leaving the patient unable to walk and permanently paralyzed. Previous studie
-
After publishing acupuncture research in Nature and revealing the existence of acupuncture points, Harvard full professor Ma Qiufu returned to China and joined Westlake University
Time of Update: 2023-01-06
In October 2021, Ma Qiufu's team and others published a paper in Nature to achieve a historic breakthrough in acupuncture research, which showed a class of PROKR2-Cre-labeled dorsal root ganglia (DRG) Sensory neurons are essential for low-intensity acupuncture stimulation to activate the vagus-adrenal anti-inflammatory pathway.
-
Memory loss is Alzheimer's disease? Diagnosis pays attention to these 4 points
Time of Update: 2023-01-06
Download the decision assistant App, the guide is free at any time ~ References: [1] Diagnosis and treatment norms for Alzheimer's disease (2020 edition) ▼▼▼ Click to read the original article You can also download the app*For medical professionals onlyAlzheimer's disease is not an inevitable occurrence of human aging, it is a disease.
-
Memory loss is Alzheimer's disease? Diagnosis pays attention to these 4 points
Time of Update: 2023-01-06
Download the decision assistant App, the guide is free at any time ~ References: [1] Diagnosis and treatment norms for Alzheimer's disease (2020 edition) ▼▼▼ Click to read the original article You can also download the app*For medical professionals onlyAlzheimer's disease is not an inevitable occurrence of human aging, it is a disease.
-
The brain cells in the petri dish also play the electronic batting game Neuron
Time of Update: 2023-01-06
Image credit: Cortical LabsSOURCE: CORTICAL LABSTranslated by Shilin ShuEdited by Wei XiaoA team of scientists led by scientists in Melbourne, Australia, has demonstrated for the first time that 800,000 brain cells living in a petri dish can perform goal-directed tasks — in this case, playing the simple tennis-like computer game "Pong.
-
The brain cells in the petri dish also play the electronic batting game Neuron
Time of Update: 2023-01-06
Image credit: Cortical LabsSOURCE: CORTICAL LABSTranslated by Shilin ShuEdited by Wei XiaoA team of scientists led by scientists in Melbourne, Australia, has demonstrated for the first time that 800,000 brain cells living in a petri dish can perform goal-directed tasks — in this case, playing the simple tennis-like computer game "Pong.
