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Summaptan, Zolmitriptan... One article masters the treatment of "cluster headache"
Time of Update: 2023-01-06
*For medical professionals onlyThese 5 things to know!Cluster headache (CH) is often clinically manifested as severe pain in the orbital, supraorbital, and/or temporal region of the strict unilateral
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New breakthrough in brain-computer interface: Zhang Fulun's team helps paralyzed aphasia "speak" by decoding brain activity
Time of Update: 2023-01-06
75em;"> style="margin-bottom: 0px;text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;">Open reprint, welcome to forward to Moments and WeChat groups EditorWang Duoyu TypesettingShui Chengwen Neuroprosthesis is a device that replaces missing nervous system function and is expected to restore the ability to communicate in patients who are unable to speak or type due to paralysis.
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Nature: Cai's team reveals how the Alzheimer's disease gene APOE4 damages the brain and finds potential therapies
Time of Update: 2023-01-06
Paper link: style="color: rgb(136, 136, 136);font-size: 12px;" _mstmutation="1" _istranslated="1"> open reprint, welcome to forward to the circle of friends and WeChat group Written by NagashiEditorWang DuoyuTypesettingWater writingAlzheimer's disease (AD), commonly known as "Alzheimer's disease", is a type of central nervous system degenerative disease that mainly occurs in the elderly and is characterized by progressive cognitive dysfunction and behavioral damage.
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Distal ischemia preconditioning intervention after moderate ischaemic stroke
Time of Update: 2023-01-06
commentsGiven that 6% of patients were rapidly excluded after randomization, that results had not been reported by the primary intention-to-treat analysis pre-specified in the statistical analysis plan, and that the trial was open-label rather than sham designed, this is particularly concerning because of the importance of proof-of-principle trials evaluating novel therapies for stroke.
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Changes in consciousness after a fall in patients with spinal cord injury Clinical reasoning
Time of Update: 2023-01-06
What are the next steps for the assessment?Part IIIPunctate diffusion restriction and microbleeding suggest that the lesion involves small blood vessels, and differential diagnoses include vasculitis, microangiopathy, or embolism.
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There are so many vertigo terms, how to distinguish them?
Time of Update: 2023-01-06
Come to the "doctor's station" and take a look 👇Vertigoof self-movement that is distorted during normal head movement, in short, the feeling that oneself is moving(not actually moving),which is different from external vertigo, which refers to the "external" visual motor sensation or oscilloscope[vestibular visual symptoms, in short, seeing something moving (in fact neither you nor the thing moving)].
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Primary VS secondary trigeminal neuralgia, what is the difference?
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time~References:[1] Chinese expert consensus on the diagnosis and treatment of trigeminal neuralgia▼▼▼Click to read the original article to download the App*For medical professionals onlyScientific response to the "world's first pain"!
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For the first time, the journal Nature found that the abnormal protein construction of Parkinson's disease is inseparable from this molecule
Time of Update: 2023-01-06
▎ WuXi AppTec content team editor Parkinson's disease currently plagues more than 6 million patients worldwide, and the distinctive feature of the disease is abnormal α-synuclein clumps in the brain 。
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Dev Cell—Tian Ye's team found that the GPCR signaling pathway coordinates the body's mitochondrial stress response in a pair of sensory neurons
Time of Update: 2023-01-06
Written by Liu Yangli, edited by Zhou Jun -- Wang Sizhen, edited by Fang Yiyi -- Xia YeThe nervous system plays an important role in sensing and coordinating the body's stress response. When the mitoc
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NEJM sub-journal: Improve the cognition of people with mild cognitive impairment, crossword puzzles are very good!
Time of Update: 2023-01-06
In addition, in subjects with late MCI, the change in ADAS-Cog score was manifested as cognitive decline in the computer game group and improvement in cognitive function in the crossword group at week 12 (LS mean difference: -1.
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Patients can use efgartigimod early and seek greater benefits! 2022 AANEM Essence Hot Review No. 3
Time of Update: 2023-01-06
Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies, with impaired transmission of acquired neuro-muscle junctions (NMJs). 。 Acetylcholine receptor (AChR) antibodies are the mos
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Academician Cell Review! Xu Huaqiang/Xie Xin/Wang Mingwei/Zhuang Youwen revealed the mechanism of action of morphine and fentanyl, and powerful analgesics got rid of addiction one step further
Time of Update: 2023-01-06
iNatureOn November 10, 2022, the team of Xu Huaqiang, Xie Xin, and Wang Mingwei, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, cooperated in publishing a long article entitled "Mo
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Can cerebral infarction in elderly patients be thrombolysis? See what the top issue has to say!
Time of Update: 2023-01-06
A 2014 review published in Lancet in nine clinical trials (6756 patients with ischemic stroke treated with alteplase) (Figure 2) showed that people over 80 years of age still benefit from intravenous thrombolysis with alteplase within 3.
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Winning Zai Future Elite Club, MG Youth Original Scientific Research Forum 2022 Summit Wonderful Review
Time of Update: 2023-01-06
In the past 10 years, research results in the field of myasthenia gravis (MG) in China have emerged, and the number of papers published has ranked among the top in the world. In order to further encou
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The risk of stroke in young people has risen dramatically! JAMA is here to give you a wake-up call
Time of Update: 2023-01-06
conclusionUsing data from the Oxford Vascular Study, the researchers explored whether stroke rates changed between 2002 and older people in young and old people, which included 94,567 people registered at GP clinics in Oxfordshire.
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Migraine attacks suffering? Finding the right medicine is key!
Time of Update: 2023-01-06
▼▼▼Click to read the original article to download the AppDownloadDecision Assistant App, the guide is free at any time~References:References:[1] Guidelines for the prevention and treatment of migraine in China (2016).
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Hu Gang's team revealed that microglia promote toxic astrocytes formation and induce depression-like behavior
Time of Update: 2023-01-06
1038/s41586-022-05328-2The images in the article are from referencesFigure 1: Increased activation of hippocampal neurotoxic astrocytes after stress2NLRP3 regulates the increase of astrocytes in the hippocampusGiven that NLRP3 regulates phenotypic transitions in A1 astrocytes and increases hippocampal NLRP3 levels after CMS, they constructed NLRP3 total knockout mice and found that knocking out NLRP3 was able to attenuate CMS-induced depression-like behavioral disorders, reduce the number of hippocampal A1 astrocytes, and attenuate synaptic protein loss.
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Neuron Mo Wei/Zhang Liang/Hu Jin of Xiamen University revealed that microglia sense amyloid plaque hardness through Piezo1 to limit the progression of Alzheimer's disease
Time of Update: 2023-01-06
Original link: 00954-0—END—The content is [iNature]iNatureThe pathological feature of Alzheimer's disease (AD) is extracellular amyloid-β (Aβ) plaques, the effect of which on the mechanical properties of surrounding brain tissue is unknown.
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GnRH replacement therapy has had amazing benefits for people with Down syndrome
Time of Update: 2023-01-06
European researchers have observed that DS patients also have fewer neurons producing gonadotropin-releasing hormone (GnRH) over time, so they wanted to understand whether this was the cause of cognitive loss.
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Nature: Zhong Haining's team discovered the brain's "brake" mechanism for motor control, opening up a new avenue for Parkinson's disease treatment
Time of Update: 2023-01-06
On November 10, 2022, the team of Zhong Haining of the Vollum Institute of Oregon Health and Science University published a report in Nature entitled Locomotion activates PKA through dopamine and adenosine in striatal neurons Research papers.
