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Stroke: the association between stroke and suicide risk
Time of Update: 2021-03-21
The researchers screened 4093 articles and finally included 23 studies of comparable quality, accumulating more than 2 million stroke survivors, including 5563 suicide attempts or suicide deaths.
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Lancet Neurology: Comparison of eight prehospital stroke scales for detecting intracranial occlusion of large vessels in patients with suspected stroke: a prospective observational study
Time of Update: 2021-03-21
After training, medical staff used mobile apps to evaluate 8 prehospital stroke scales, namely: Rapid Arterial Occlusion Assessment (RACE), Los Angeles Exercise Scale (LAMS), Cincinnati Stroke Classification Assessment Tool (C-STAT), Gaze-Facial Arm Language Time (G-FAST), Prehospital Acute Stroke Severity (PASS), Cincinnati Prehospital Stroke Scale (CPSS), convenient field assessment stroke classification (CG-FAST) and FAST-PLUS (face -Arm-Language-Time+Severe arm or leg movement defect) test.
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Stroke: Predictive effects of risk factors during pregnancy on cerebrovascular disease in offspring
Time of Update: 2021-03-21
The researchers used the Cox proportional hazard model to evaluate the relationship between pregnancy and childbirth complications and the incidence of cerebrovascular disease in the offspring, and adjusted it according to factors such as gender, family socioeconomic status, pregnant women's age, and smoking during pregnancy.
Pregnancy Risk Factors as Predictors of Offspring Cerebrovascular Disease The Northern Finland Birth Cohort Study 1966 .
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Stroke: The relationship between plasma neurofilament light chain and cerebral small vessel disease in the elderly without dementia
Time of Update: 2021-03-21
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels published on the prestigious journal Stroke the areas of disease research article, the researchers aimed to assess the elevated levels of plasma NfL whether the role of monitoring the progress of non-demented elderly cerebral small vessel disease (CSVD), CSVD It is prevalent in the elderly and is associated with an increased risk of stroke and dementia.
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JAMA Neurology: Hypertension accelerates the occurrence of dementia, can intensive blood pressure lowering prevent Alzheimer's disease?
Time of Update: 2021-03-21
When the systolic blood pressure of middle-aged hypertensive patients exceeds 130mmHg, the risk of cognitive impairment increases significantly.
When the systolic blood pressure of middle-aged hypertensive patients exceeds 130mmHg, the risk of cognitive impairment increases significantly.
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Lancet Neurology: Safety and Efficacy of Tiranezumab in the Treatment of Progressive Supranuclear Palsy: A Phase 2 Randomized Placebo Controlled Trial
Time of Update: 2021-03-21
Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
The Lancet Neurology, Volume 20, Issue 3, 182-192 Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
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JNNP: The clinical spectrum of high-titer GAD65 antibodies
Time of Update: 2021-03-21
Here, this article evaluates the clinical manifestations, immunotherapy response, and results of a large cohort of patients with high titers of GAD65 antibodies.
do?w=%E7%99%AB%E7%97%AB">Epilepsy Here, this article evaluates the clinical manifestations, immunotherapy response, and results of a large cohort of patients with high titers of GAD65 antibodies.
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Nat Commun: A meta-analysis study of brain and nervous system activities related to placebo analgesia
Time of Update: 2021-03-21
These studies and the meta-analysis of findings also provide relevant evidence for the study of brain regions related to pain processing, including early pain control mechanisms, and other forms of learning and social cognition related to healthy behaviors.
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Clin Transl Med: First discovery of a gradual freezing compound
Time of Update: 2021-03-21
Hande Ozdinler, associate professor of neurology at Northwestern University School of Medicine, said that even though upper motor neurons are responsible for the initiation and regulation of exercise, their degeneration is an early event of ALS, but so far, there is no treatment plan to improve their health.
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Neurobiology research: "loneliness" is the opposite of "wisdom", the smarter you are, the less you will feel lonely
Time of Update: 2021-03-21
Recently, in a new study published in "cerebral cortex", a research team from the University of California, San Diego (UCSD) found that our brain’s response to loneliness is almost completely opposite to the response to wisdom, and those who think they are The smarter people will not feel lonely.
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JNNP: Quantitative analysis of SPECT autopsy confirmed cases in patients with Lewy body dementia, Parkinson's disease and Alzheimer's disease
Time of Update: 2021-03-21
The purpose of this study is to use in vivo 123 I- FP-CIT (quantitative brain SPECT analysis, reassess the differentiation of patients with DLB, AD and PD on the basis of neuropathological diagnosis.
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AD/PD 2021: Special sound and light stimulation to overcome Alzheimer's disease!
Time of Update: 2021-03-21
At the 15th International Conference on Alzheimer’s and Parkinson’s Disease (AD/PD™2021) held recently in 2021, Cognito Therapeutics announced the Phase 2 clinical study data of digital therapy gamma frequency neuromodulation ( Phase 2 means that it will be available on the market soon).
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Neurology: Icotinizumab can effectively reduce the number of migraine days per month in patients with chronic migraine
Time of Update: 2021-03-21
Humanized anti-calcitonin gene-related peptide monoclonal antibody--Etinizumab is the only drug approved for the prevention of CM, a phase 3, multi-center, randomized, double-blind, placebo-controlled, parallel group The study evaluated the efficacy and safety of Icotinizumab in the prevention and treatment of chronic migraine (CM), and confirmed that a single dose of Icotinizumab can reduce the average number of migraine days per month in patients with CM.
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JNNP: Application of psychotropic drugs and analgesics in patients with traumatic brain injury-a cohort study of 240,000 people in Sweden
Time of Update: 2021-03-21
do?w=%E7%99%AB%E7%97%AB">Epilepsy In order to resolve the uncertainties in the use of psychotropic drugs and painkillers, this article investigated a group of people with traumatic brain injury.
In order to resolve the uncertainty in the use of psychotropic drugs and analgesics, this article surveyed a group of people with traumatic brain injury.
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Neurology: Lowering "good cholesterol" can increase the risk of Parkinson's disease by 60%
Time of Update: 2021-03-21
Numerous previous studies have shown that there is an inverse relationship between a decrease in high-density lipoprotein cholesterol and an increased risk of coronary heart disease and myocardial infarction.
Reference: Association of High-Density Lipoprotein Cholesterol Variability and the Risk of Developing Parkinson Disease.
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The cause of chronic pain in depressed patients has been found!
Time of Update: 2021-03-21
They found that different thalamic cortical circuits are the basis for allodynia caused by tissue damage and depression-like states.
Different subnuclei of the thalamus are involved in allodynia from tissue damage and depression-like states.
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ATVB: The role of carotid atherosclerosis in predicting coronary artery disease
Time of Update: 2021-03-21
The primary endpoint of the study is the correlation between carotid artery intima-media thickness (CIMT) and carotid plaque characteristics (calcification and lipid-rich necrotic core) with coronary artery disease (CAD).
Carotid Atherosclerosis in Predicting Coronary Artery Disease A Systematic Review and Meta-Analysis .
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Mov Disord: Patients with type 2 diabetes are at increased risk of Alzheimer's disease!
Time of Update: 2021-03-21
Correlation between diabetes and PD riskCorrelation between diabetes and PD riskIn the observational analysis part, the summary effect estimate shows that T2DM is associated with an increased risk of PD (odds ratio [OR] 1.
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Stroke: Spontaneous Carotid Dissection in Patients with Vascular Ehlers-Danlos Syndrome
Time of Update: 2021-03-21
Local dissections and aneurysms are the most common types of lesions, but transient ischemic attacks or strokes are rare .
Carotid artery disease is common in patients with vascular Ehlers-Danlos syndrome, and most of them are asymptomatic.
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J Ethnopharmacol: Ashwagandha root extract can improve sleep quality and help manage insomnia
Time of Update: 2021-03-21
Recently, a randomized, parallel group, stratified design, placebo-controlled study evaluated the pharmacological effects of Ashwagandha root extract on sleep in healthy subjects and insomnia subjects, and found that Ashwagandha root extract can improve sleep quality and help For the management of insomnia, the results have been published in J Ethnopharmacol.
