-
Stroke: Analysis of Risk Factors for Cerebral Hemorrhage in Patients with Atrial Fibrillation Stroke Using Non-Vitamin K Antagonist Oral Anticoagulants
Time of Update: 2021-03-21
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels published a research article on the disease areas prestigious journal Stroke, prospective, multicenter, multinational, cases not matched control study was designed to (1) explore can predict the occurrence of ICH patients with atrial fibrillation treated during NOAC Risk factors, and (2) assess the role of CHA2DS2-VASc and HAS-BLED.
-
Neurology: Icotinizumab can effectively reduce the number of migraine days per month in patients with chronic migraine
Time of Update: 2021-03-21
Humanized anti-calcitonin gene-related peptide monoclonal antibody--Etinizumab is the only drug approved for the prevention of CM, a phase 3, multi-center, randomized, double-blind, placebo-controlled, parallel group The study evaluated the efficacy and safety of Icotinizumab in the prevention and treatment of chronic migraine (CM), and confirmed that a single dose of Icotinizumab can reduce the average number of migraine days per month in patients with CM.
-
Lancet Neurology: Safety and Efficacy of Tiranezumab in the Treatment of Progressive Supranuclear Palsy: A Phase 2 Randomized Placebo Controlled Trial
Time of Update: 2021-03-21
Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
The Lancet Neurology, Volume 20, Issue 3, 182-192 Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
-
Clin Transl Med: First discovery of a gradual freezing compound
Time of Update: 2021-03-21
Hande Ozdinler, associate professor of neurology at Northwestern University School of Medicine, said that even though upper motor neurons are responsible for the initiation and regulation of exercise, their degeneration is an early event of ALS, but so far, there is no treatment plan to improve their health.
-
Stroke: the association between stroke and suicide risk
Time of Update: 2021-03-21
The researchers screened 4093 articles and finally included 23 studies of comparable quality, accumulating more than 2 million stroke survivors, including 5563 suicide attempts or suicide deaths.
-
JNNP: Application of psychotropic drugs and analgesics in patients with traumatic brain injury-a cohort study of 240,000 people in Sweden
Time of Update: 2021-03-21
do?w=%E7%99%AB%E7%97%AB">Epilepsy In order to resolve the uncertainties in the use of psychotropic drugs and painkillers, this article investigated a group of people with traumatic brain injury.
In order to resolve the uncertainty in the use of psychotropic drugs and analgesics, this article surveyed a group of people with traumatic brain injury.
-
Mov Disord: Patients with type 2 diabetes are at increased risk of Alzheimer's disease!
Time of Update: 2021-03-21
Correlation between diabetes and PD riskCorrelation between diabetes and PD riskIn the observational analysis part, the summary effect estimate shows that T2DM is associated with an increased risk of PD (odds ratio [OR] 1.
-
Stroke: Spontaneous Carotid Dissection in Patients with Vascular Ehlers-Danlos Syndrome
Time of Update: 2021-03-21
Local dissections and aneurysms are the most common types of lesions, but transient ischemic attacks or strokes are rare .
Carotid artery disease is common in patients with vascular Ehlers-Danlos syndrome, and most of them are asymptomatic.
-
Stroke: Predictive effects of risk factors during pregnancy on cerebrovascular disease in offspring
Time of Update: 2021-03-21
The researchers used the Cox proportional hazard model to evaluate the relationship between pregnancy and childbirth complications and the incidence of cerebrovascular disease in the offspring, and adjusted it according to factors such as gender, family socioeconomic status, pregnant women's age, and smoking during pregnancy.
Pregnancy Risk Factors as Predictors of Offspring Cerebrovascular Disease The Northern Finland Birth Cohort Study 1966 .
-
Neurology: Lowering "good cholesterol" can increase the risk of Parkinson's disease by 60%
Time of Update: 2021-03-21
Numerous previous studies have shown that there is an inverse relationship between a decrease in high-density lipoprotein cholesterol and an increased risk of coronary heart disease and myocardial infarction.
Reference: Association of High-Density Lipoprotein Cholesterol Variability and the Risk of Developing Parkinson Disease.
-
ATVB: The role of carotid atherosclerosis in predicting coronary artery disease
Time of Update: 2021-03-21
The primary endpoint of the study is the correlation between carotid artery intima-media thickness (CIMT) and carotid plaque characteristics (calcification and lipid-rich necrotic core) with coronary artery disease (CAD).
Carotid Atherosclerosis in Predicting Coronary Artery Disease A Systematic Review and Meta-Analysis .
-
JNNP: Quantitative analysis of SPECT autopsy confirmed cases in patients with Lewy body dementia, Parkinson's disease and Alzheimer's disease
Time of Update: 2021-03-21
The purpose of this study is to use in vivo 123 I- FP-CIT (quantitative brain SPECT analysis, reassess the differentiation of patients with DLB, AD and PD on the basis of neuropathological diagnosis.
-
Multiple sclerosis Journal: Looking for suspected culprits of cortical axon loss in PMS patients
Time of Update: 2021-03-21
1177/1352458520918978" target="_blank" rel="noopener">Cortical axonal loss is associated with both gray matter demyelination and white matter tract pathology in progressive multiple sclerosis: Evidence from a combined MRI-histopathology study .
-
Alzheimer's Dementia: Blood AD biomarker concentration is related to pathology and clinical diagnosis
Time of Update: 2021-03-21
It was found that the AD biomarker concentration in blood is related to pathology and clinical diagnosis, and can predict the future development of clinical AD, providing evidence that can be included in multi-ethnic and community studies.
-
Microbiome: Fecal bacteria transplantation promotes nerve function recovery
Time of Update: 2021-03-21
FMT can promote the functional recovery of mice with spinal cord injury, promote neuronal axon regeneration, improve animal body weight and metabolic characteristics, and enhance the integrity of the intestinal barrier and gastrointestinal motility.
-
Several international authoritative journals refocus on the gut-brain axis!
Time of Update: 2021-03-21
Big data studies confirm that enterobacteria capsules and colonoscopic enterobacteria transplantation have the most significant effects on disease intervention | Intestinal Jun Weekly Issue 152: A major study in a sub-publish of "Nature"!
How does intestinal bacteria transplantation colonization and treatment of disease effects are regulated by host immunity | Changjun Jun Weekly No.
-
Stroke: The efficacy of active oxygen scavengers in patients with acute cerebral hemorrhage
Time of Update: 2021-03-21
ScreeningIt can be seen that the ROS scavenger significantly reduces the volume of PHE in patients with acute cerebral hemorrhage, and shortens the time to reach the target value of the RASS sedation assessment table and the hospital stay in the intensive care unit .
-
Eur Radiol: You must pay attention to this sign on T2WI after cervical spinal cord trauma!
Time of Update: 2021-03-21
do?w=%E7%99%AB%E7%97%AB">epilepsy Recently, a study published in the journal European Radiology evaluated the occurrence of distal intramedullary signal changes consistent with WD after traumatic spinal cord injury (tSCI) in conventional MRI and its correlation with clinical and neurophysiological damage.
-
Behavioural Brain Research: Disruption of cortical-motor interaction in Parkinson's disease
Time of Update: 2021-03-21
The purpose of this article is to explore the relationship between EEG alpha and low/high-beta band power and exercise results in a padless finger tap task, and compare it between a group of Parkinson’s disease participants and a group of healthy controls These measurements.
-
JAMA Netw Open: Collaborative care helps improve the prognosis of adolescents with persistent post-concussion syndrome (PPCS)
Time of Update: 2021-03-21
Recently, a study published in the journal JAMA Netw Open revealed that compared with conventional care, adolescent patients receiving collaborative care relieved their PPCS symptoms at 3 and 12 months and improved their quality of life.
