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Mov Disord: Patients with type 2 diabetes are at increased risk of Alzheimer's disease!

 Last Update: 2021-03-21
 Source: Internet
 Author: User

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Type 2 diabetes (T2DM) and Parkinson's disease (PD) are common diseases in the elderly.

diabetes

This study conducted a meta-analysis of observational and genetic summary data to investigate whether T2DM is a determinant of PD .

Study whether T2DM is a determinant of PD Study whether T2DM is a determinant of PD

By searching 6 databases, the highest quality observational studies were screened to assess the correlation between T2DM and PD risk and progression.

Correlation between diabetes and PD risk

In the observational analysis part, the summary effect estimate shows that T2DM is associated with an increased risk of PD (odds ratio [OR] 1.

T2DM is associated with increased risk of PD (odds ratio [OR] 1.

Correlation between diabetic and PD patients with reduced motor function

Using MR studies, researchers found some evidence that supports a causal effect between diabetes and PD risk (inverse variance weighted OR 1.

There is a causal effect between diabetes and PD risk.

T2DM has an impact on the risk of PD, and there is new evidence to support its role in the progression of PD.

Original source:

Chohan Harneek, Senkevich Konstantin, Patel Radhika K et al.

org/10.
1002/mds.
28551">Type 2 Diabetes as a Determinant of Parkinson 's Disease Risk and Progression in this message

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