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Large-scale research observes: the brains of homosexuals are different from heterosexuals
Time of Update: 2021-03-22
In August 2019, a large genome-wide association analysis (GWAS) of nearly 500,000 people published in Science magazine showed that there is no single "homosexual gene" that affects sexual orientation [1].
However, the neurobiological association of sexual orientation and the relationship between genetic factors and brain structural variations have not been well studied.
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Come to challenge: diagnosis and treatment of Parkinson's disease, try your skills in 7 cases!
Time of Update: 2021-03-22
The T2-weighted image of the MRI of the brain of patients with MSA shows a cross-shaped (bread) sign in the axial view of the pons (see Figure 3).
The following MRI brain T2-weighted image shows the "double panda sign" characteristic of Wilson disease.
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Drug treatment strategies and dosage optimization for epilepsy, mastered in one article
Time of Update: 2021-03-22
*Only for medical professionals to read for reference. Pure dry goods sharing, bookmarked! Epilepsy (epilepsy), commonly known as "saw horn wind" or "sheep epilepsy", is a chronic disease in which t
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Cell Stem Cell: Key protein promotes spinal injury repair
Time of Update: 2021-03-22
Animals engineered to overproduce SOX2 in NG2 glial cells have significantly better motor skills in the weeks after spinal cord injury than animals that produce normal SOX2In the end, researchers may be able to find a safe and effective way to overproduce SOX2 in human spinal cord injury patients, thereby helping them repair the damage with new neurons while reducing the formation of scar tissue.
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Suzhou Nano Institute developed nano-medicine-mediated stem cell therapy for Alzheimer's disease
Time of Update: 2021-03-22
The water maze behavior of AD mice after a single treatment for 1 and 6 months The analysis showed good memory and cognitive improvement (Figure 3).
Related research results were published on Advanced Materials with the title A Nanoformulation-Mediated Multifunctional Stem Cell Therapy with Improved Beta-Amyloid Clearance and Neural Regeneration for Alzheimer's Disease.
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Can Alzheimer's be treated without injections and medicine?
Time of Update: 2021-03-22
The results of the study found that compared with placebo treatment, AD patients who received gamma frequency neuromodulation therapy had significant improvements in memory, cognition, and brain atrophy and volume reduction.
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Clopidogrel and ticagrelor are both antiplatelet drugs. What are the differences?
Time of Update: 2021-03-22
8. The results of antiplatelet therapy studies on patients with gout/hyperuricemia show that long-term use of ticagrelor can increase the risk of gout.
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Early evaluation and emergency treatment of stroke, ultra-fine summary
Time of Update: 2021-03-22
A. Recommendations for blood pressure management: If blood pressure rises after ischemia or hemorrhagic stroke, more urgent treatment is generally not needed unless there are other medical diseases (myocardial infarction, heart failure, aortic dissection).
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Recalling the past and learning the new: Structural images of progressive supranuclear palsy-update and correction
Time of Update: 2021-03-22
In 2016, I wrote the first short article on Yimaitong on a night of overtime work, "Progressive Supranuclear Palsy MRI Features Only Know the Hummingbird Sign?
The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy.
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Why is the late night instant noodles so attractive?
Time of Update: 2021-03-22
Why do people like to smell food so much late at night?Recently, an article titled "Hunger enhances food-odour attraction through a neuropeptide Y spotlight" published by researchers from Harvard Medical School in the top journal "Nature" revealed that the sense of smell can pass through AGRP neurons in the brain under hunger.
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The FASEB J: Demystifying the molecular mechanism of the human brain's response to injury
Time of Update: 2021-03-22
The FASEB JournalIn the article, researchers discovered for the first time that metalloproteinase-2 (MMP2) secreted by endothelial cells may induce cell damage response processes.
Researchers have observed that endothelial cells not only promote the migration of neural stem cells, but also promote cell aggregation by secreting MMP2.
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The era of gene therapy is here!
Time of Update: 2021-03-22
Participants who successfully registered for the Shanghai 2021 BPIT conference will receive a limited edition of "CAR-T Cell Therapy Industry Research Report" 2021.
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Frontier | AI discovers 15 potential therapies for Alzheimer's disease, and 5 JAK inhibitors on the list
Time of Update: 2021-03-22
They found that 15 drugs that have been approved by the FDA have the potential to treat AD, and 5 of them are JAK kinase inhibitors.
In this research, scientists used machine learning technology to build an artificial intelligence system called Drug Repurposing In Alzheimer's Disease (DRAID).
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Nat Commun: Key proteins affect the development of Huntington's disease
Time of Update: 2021-03-22
html">Huntington's disease driven by slowed protein-building machinery in cellsOriginal source: Mehdi Eshraghi et al, Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease, Nature Communications (2021).
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20 early signs of Alzheimer's disease, what do you know?
Time of Update: 2021-03-22
According to the Alzheimer's Association, one of the early symptoms of AD is difficulty in processing numbers.
Some people find it difficult to follow the plan, but this does not mean that they are at risk of AD.
Yimaitong compiled from: 20 early signs of Alzheimer's disease.
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Research reveals the neural computer system of communication reasoning
Time of Update: 2021-03-22
Researchers have discovered that the ventromedial prefrontal lobe of the listener’s brain may be an "analog generator" of rational communication signals, which flexibly and quantitatively represents the conditional probability of various cooperative behaviors of the speaker (for example, in order to refer to the blue circle And the possibility of choosing the word "blue").
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Can Alzheimer's disease be treated without medicine?
Time of Update: 2021-03-22
Subsequently, Professor Lihui Cai’s team published papers in "Cell" and Neuron, which further clarified the mechanism of using acousto-optic stimulation to clear amyloid deposits in mouse models and improve the cognitive ability of mice.
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Science journal: Antisense oligonucleotides are expected to treat MECP2 duplication syndrome
Time of Update: 2021-03-22
Researchers from Baylor College of Medicine in the United States have previously found that antisense oligonucleotide (ASO) therapy can reduce the level of MeCP2 protein in a mouse model of MDS and reverse its disease characteristics.
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Nat Neurosci | Zhang Zhi/Li Juan collaborate to reveal the neural circuit basis of different pain
Time of Update: 2021-03-22
On March 8, 2021, Zhang Zhi’s group and Li Juan’s team from the Department of Anesthesiology, The First Affiliated Hospital of China University of Science and Technology (Anhui Provincial Hospital) jointly published an article on Nature Neuroscience "Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression -like states", found that the body pain caused by depression and the pain caused by tissue damage have a different thalamic-cortical neural circuit basis.
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Neurology: Icotinizumab can effectively reduce the number of migraine days per month in patients with chronic migraine
Time of Update: 2021-03-21
Humanized anti-calcitonin gene-related peptide monoclonal antibody--Etinizumab is the only drug approved for the prevention of CM, a phase 3, multi-center, randomized, double-blind, placebo-controlled, parallel group The study evaluated the efficacy and safety of Icotinizumab in the prevention and treatment of chronic migraine (CM), and confirmed that a single dose of Icotinizumab can reduce the average number of migraine days per month in patients with CM.
