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Nat Comm | Pan Yongxin/Guo Weixiang's collaborative team reveals that sub-magnetic field exposure weakens adult hippocampal neurogenesis and cognitive function in mice
Time of Update: 2021-03-23
In addition, returning mice exposed to long-term submagnetic fields into GMF significantly improved their adult hippocampal neurogenesis and cognition, accompanied by an increase in ROS levels.
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The first domestic "brain tumor without craniotomy" operation!
Time of Update: 2021-03-23
Recently, the team of Professor Jia Wang from the Department of Neurosurgery of Beijing Tiantan Hospital affiliated to Capital Medical University successfully implemented the first domestic “Magnetic Resonance-guided Laser Interstitial Thermal Therapy (LITT)” in China, bringing more benefits to patients with brain tumors.
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In addition to liver cirrhosis, these reasons can also lead to hyperammonemic encephalopathy!
Time of Update: 2021-03-23
Cerebral edema, brain herniation, and seizures usually occur when acute hyperammonemia (that is, in the case of acute liver failure) results in arterial blood ammonia levels> 200 μmol/L.
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PNAS | Shi Yun/Zhang Chen collaborated to discover the maintenance mechanism of LTP
Time of Update: 2021-03-23
Recently, Shi Yun from Nanjing University and Chen Zhang from Capital Medical University published a research paper entitled The amino-terminal domain of GluA1 mediates LTP maintenance via interaction with neuroplastin-65 in PNAS, revealing the long-term potentiation of hippocampal CA1 pyramidal neurons (LTP) important molecular mechanism.
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Communications Biology: Study reveals the mechanism behind eye disease
Time of Update: 2021-03-23
html">Genetic study uncovers hidden pieces of'eye disease puzzle'Original source: Alison J.
html">Genetic study uncovers hidden pieces of'eye disease puzzle'Original source: Alison J.
html">Genetic study uncovers hidden pieces of'eye disease puzzle'Original source: Alison J.
html">Genetic study uncovers hidden pieces of'eye disease puzzle'Original source: Alison J.
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4 mind maps to clear away the knowledge points of secondary headaches, worth collecting!
Time of Update: 2021-03-23
"2018 International Classification of Headaches (Third Edition)" classifies secondary headaches as secondary to head and neck trauma; cranial or cervical vascular diseases; intracranial non-vascular diseases; substance or substance withdrawal; infection; internal Environmental disorders; disorders of the skull neck, eyes, ears, nose, sinuses, teeth, oral cavity or other craniofacial structures; headaches due to mental disorders in 8 subtypes.
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Science: Demystify!
Time of Update: 2021-03-23
Because the photosensitive lock key is very small compared to the receptor, researchers can use the laser spot to control the assembly/organization of the receptor in the cell membrane with high precision.
abb7657">Photo-induced receptor confinement drives ligand-independent GPCR signaling Science
abb7657">Photo-induced receptor confinement drives ligand-independent GPCR signaling Science
abb7657">Photo-induced receptor confinement drives ligand-independent GPCR signaling Science
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JAHA: The risk of stroke in this population has nothing to do with atrial fibrillation!
Time of Update: 2021-03-23
A recent study published in the Journal of the American Heart Association assessed the risk of ischemic stroke among American Indians and compared it with white, black, Hispanic, and Asian populations.
In short, regardless of whether they suffer from atrial fibrillation, the American Indiana population has the highest risk of ischemic stroke.
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Cell Reports | Zhou Wenhao/Xiong Man's team reveals the hidden driving factor SYTL3 that regulates early human brain development
Time of Update: 2021-03-23
On March 2, 2021, Zhou Wenhao/Xiong Man’s research team from the Pediatric Hospital of Fudan University published a paper Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment on Cell Reports.
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Double target neuroprotective agent, open the door to neuroprotection!
Time of Update: 2021-03-23
On February 25, 2021, the Phase III clinical study results conference of the Treatment of Acute Ischemic STroke with Edaravone Dexborneol (TASTE) was held at Beijing Tiantan Hospital, Capital Medical University.
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How can blood pressure be lowered when acute cerebral infarction occurs?
Time of Update: 2021-03-23
If patients with hypertension have cerebral infarction, they are prone to significantly increase blood pressure during the acute phase of the infarction.
, Why do we generally do not recommend active blood pressure reduction in the face of patients with hypertension and cerebral infarction.
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Mom is fat, and children have poor memory?
Time of Update: 2021-03-23
On March 1, 2021, Liu Xuebo and Liu Zhigang, School of Food Science and Engineering, Northwest A&F University, and Hou Min, School of Public Health, Shanghai Jiaotong University, jointly published an article in Cell Metabolism, revealing that maternal obesity can cause cognitive dysfunction in offspring mice , High dietary fiber diet can improve this cognitive impairment through the gut-brain axis.
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Neuron: Scientists have discovered a special cell type that is involved in the body's neuropathic pain-MRC1+ macrophages!
Time of Update: 2021-03-23
In the article, the researchers stated that stimulating the expression of an anti-inflammatory protein called CD163 may reduce signs of neuropathic inflammation in the spinal cord of mice with neuropathic pain.
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After 7 months of approval, it quickly entered the medical insurance, deuterium tetrabenazine reshapes the new pattern of the treatment of tardive dyskinesia!
Time of Update: 2021-03-23
Deuterium tetrabenazine entered medical insurance in the year when it was approved in my country, providing Chinese patients with new and accessible therapeutic drugs.
The AIM-TD study is a placebo-controlled fixed-dose trial involving 298 adult TD patients at a ratio of 1:1:1:1 Groups receive 12mg/24mg/36mg deuterium tetrabenazine or placebo treatment.
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Are you aware of these diseases that are diagnosed with severe muscle inability to identify them?
Time of Update: 2021-03-23
It can also be manifested as simple extraocular muscle palsy, which is easy to be misdiagnosed as MG The electromyography examination showed that the nerve conduction speed was slowed down, the cerebrospinal fluid examination showed the phenomenon of protein-cell separation, and some patients' serum could detect anti-GQ1b antibody or GT1a antibody.
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Development: Scientists have discovered that the hearing cells of fruit flies can be regenerated, bringing new hope to the study of human hearing loss therapy!
Time of Update: 2021-03-23
In a new study published in the journal Development, scientists from the Stem Cell Center of the University of Southern California describe how adult fruit flies regenerate sensory and auditory cells, and how the study of fruit flies can provide a new way to understand and develop treatments Treatments for hundreds of millions of hearing and balance disorders worldwide.
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JAMA Pediatr: Is the special phenotype of preterm infants related to differences in clinical disease, growth and neurodevelopment at 2 years of age?
Time of Update: 2021-03-23
The results of this study indicate that the maternal risk factors, less than There are different patterns in neonatal morbidity of gestational age, growth and development of newborns and children, severe morbidity, and neurodevelopment of preterm birth phenotypes.
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Subverting common sense, BMJ confirms that this scale better predicts the risk of stroke after TIA
Time of Update: 2021-03-23
Recently, a multi-center, prospective, cohort study published in BMJ to prospectively validate the Canadian Transient Ischemic Attack (TIA) score and compare it with ABCD2 and ABCD2i to assess the risk of subsequent stroke after TIA The results show that the Canadian TIA score is more accurate than ABCD2 and ABCD2i in distinguishing the risk of stroke within 7 days and the follow-up, and carotid endarterectomy/carotid stenting.
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Autoimmune encephalitis: What are the effects of neuronal autoantibodies on cognitive function?
Time of Update: 2021-03-23
2. Long-term follow-up In LGI1 encephalitis, most patients have chronic cognitive impairment, which mainly affects memory, but also has deficits in attention and executive function.
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Cell Stem Cell | In vivo reprogramming after spinal cord injury converts NG2 glial cells into neurons and promotes functional repair
Time of Update: 2021-03-23
They found that the high expression of endogenous SOX2 caused by spinal cord injury can cause NG2 glial cells to transform into DCX (a marker of neuron regeneration) positive cells, but they cannot further develop into mature neurons.