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The evidence of "Meng's mother's three relocation" is here!
Time of Update: 2021-04-23
This study provides further evidence that the neighborhood environment affects neurodegeneration and cognitive decline.
So, does the neighborhood environment affect the cognitive decline of the elderly without neurodegeneration?
In summary, this study provides further evidence that the neighborhood environment affects neurodegeneration and cognitive decline.
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Nat Commun | Revealing the secrets of the brain's memory storage
Time of Update: 2021-04-23
The second set of large-scale individual difference experiments further discovered a shared brain area circuit, in which the left inferior frontal gyrus and preinsular cortex and the core area of the default network ventromedial prefrontal cortex (vmPFC) The weakened functional connection of) is related to the better performance of the two kinds of memory retrieval.
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【Nature】Heavyweight | Scientists from New York University Discover New Tumor Suppressors, Becoming Potential Treatments
Time of Update: 2021-04-23
This article is converted Medicine original, reproduced please indicate the source Author: Yun Introduction: The recent study found that during embryonic development, a kind of enzyme protein on the cell cycle control for normal cell growth is essential, it The dysfunction can lead to fatal cell overgrowth.
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Knowing the article: the clinical classification of motor neuron disease
Time of Update: 2021-04-23
Except for amyotrophic lateral sclerosis (ALS), progressive muscular atrophy (PMA), progressive bulbar palsy (PBP) and primary lateral sclerosis (PLS) ) In addition to the 4 main clinical types, there are also relatively rare special types such as flail arm/leg syndrome.
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Science Sub-Journal: Stop working and rest upside down!
Time of Update: 2021-04-23
This study shows that in a mouse melanoma model, compared with the normal light-dark cycle (LD), the circadian rhythm disorder will lead to the loss or reversal of the levels of macrophages and cytokines in the liver and tumor tissues of the mice.
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JNNP: oligoclonal IgG band in chronic inflammatory polyneuropathy
Time of Update: 2021-04-23
There was no difference in demographic characteristics among CIDP, anti-MAG antibody neuropathy, and NINPs. The correlation between the cerebrospinal fluid protein concentration and QALB in four groups of patients.
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Sub-Journal of "Nature": There are "zombie genes" in the brain. People die, but they live
Time of Update: 2021-04-23
Selective time-dependent changes in human brain activity and cell-specific gene expression after death Next, the researchers performed histological observations on brain tissue samples within 24 hours of brain death and discovered three types of genes.
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Express | 85% of patients with early-stage multiple sclerosis have no disease progression, and the latest results of Roche's heavy CD20 antibody are gratifying
Time of Update: 2021-04-23
The interim data analysis of the open-label Phase 3b clinical trial ENSEMBLE showed that 85% of patients with early relapsing-remitting multiple sclerosis (RRMS) had not shown any signs of disease progression after receiving Ocrevus for 48 weeks.
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The risk of visual and hearing impairment or dementia is 2 times higher
Time of Update: 2021-04-23
April 7, 2021, the American Academy of Neurology published in Neurology "The study said: Loss of hearing or vision function may put patients at greater risk of dementia and cognitive decline years later.
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Sleep: Sleep snoring increases the risk of dementia, and timely treatment can reduce the risk
Time of Update: 2021-04-23
OSAS is the apnea and hypoventilation caused by the blockage or narrowing of the upper airway during sleep, which causes symptoms such as night snoring, apnea, and abnormal sleep structure, which causes repeated occurrence of hypoxia, daytime sleepiness, lack of concentration, etc.
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Chinese Voice|Is the activity change of the subthalamic nucleus related to the severity of Parkinson's disease?
Time of Update: 2021-04-23
The study concluded that STN neurons have a higher firing rate, and β-oscillating neurons are more common in the brain on the side with more severe motor retardation.
Yimaitong compiled from: Increases in subthalamic neuronal firing rate and β frequency neuronal activity in the two hemispheres associated with severity of Parkinson's disease.
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China is approved for listing!
Time of Update: 2021-04-23
▎The content team editor of WuXi AppTec recently announced on the official website of China National Medical Products Administration (NMPA) that Biogen's dimethyl fumarate (English trade name: Tecfidera; English common name: dimethyl fumarate) enteric-coated capsules The marketing application was officially approved for the treatment of relapsing multiple sclerosis (MS).
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Nature︱ Breakthrough! How astrocytes close the critical period of motor neuron circuits
Time of Update: 2021-04-23
Figure 4 Signal transduction of astrocytes and motor neurons will limit dendritic plasticity and end the critical period (picture quoted from: Sckerman, SD, Perez-Catalan, NA, Freeman, MR et al.
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The latest research confirms: Doing more housework will make your brain healthier
Time of Update: 2021-04-23
Researchers studied the correlation between housework, brain volume, and cognition of 66 cognitively healthy elderly people in the community, and conducted three assessments of participants, including health assessment, brain structure imaging, and cognitive assessment.
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New England: Platelet factor 4 antibody produced after the first dose of AstraZeneca vaccination leads to thrombosis
Time of Update: 2021-04-23
A particularly noteworthy safety signal related to the use of the ChAdOx1 novel coronavirus -19 vaccine (AstraZeneca) was recently reported, involving abnormal clinical coagulation abnormalities, especially cerebral venous thrombosis and thrombocytopenia, which in some cases caused death.
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JNNP: Longitudinal observational study on evaluation of clinical trial results of inclusion body myositis
Time of Update: 2021-04-23
IBM's outcome measures include physical function assessment (for example, IBM Function Rating Scale (IBMFRS) and IBM Body Function Assessment), muscle strength (for example, manual muscle test (MMT), quantitative muscle test (QMT), and hand-held dynamometer ), mobility/endurance (for example, 6 min walking distance and timed up and down test) and imaging features, including MRI thigh muscle volume and fat fraction.
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The placenta-derived, allogeneic, natural killer NK cell therapy was awarded the FDA orphan drug title for the treatment of glioblastoma|Yi Mai Meng broke the news
Time of Update: 2021-04-23
Recent popular reports from Yimaike ★ NK cell therapy has been certified by the FDA for fast-track treatment for the treatment of recurrent glioblastoma multiforme in adults Yimai broke the news ★The
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How to pronounce cranial CT?
Time of Update: 2021-04-23
A. Schematic diagram showing that acute subdural hematoma compresses the left cerebral hemisphere and lateral ventricle, causing the midline to shift.
B. Axial CT plain scan showed a typical acute subdural hematoma extending along the convex surface of the left side of the brain and compressing the subarachnoid space below.
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Hot and cold, sour and sweet, why can't you eat as you want?
Time of Update: 2021-04-23
In order to study the key cold-conducting ion channel protein of inflammatory tooth pain, the researchers respectively constructed model mice with lack of TRPC5, TRPA1 and TRPM8 and dental pulp injury (DPI).
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Cerebral infarction occurred twice in a year, and it turned out to be the culprit!
Time of Update: 2021-04-23
It was also because of ambulatory blood pressure monitoring that I discovered that my friend's mother had hidden hypertension, which basically clarified the cause of her 2 cerebral infarctions within a year.
