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Alzherimer's&Dementia | Clinical discovery: BBB water exchange rate is expected to predict the occurrence of Alzheimer's!
Time of Update: 2021-05-21
So, is the water exchange rate of BBB really related to the occurrence of AD and the changes in cerebrospinal fluid biomarkers, such as Aβ clearance?
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JAD: 12-minute meditation practice may help prevent or reverse cognitive decline!
Time of Update: 2021-05-21
Prevent blood vesselsRecently, a new study published in the Journal of Alzheimer's Disease found that mental health is a new medical concept centered on mental and mental health, and a simple 12- minute meditation practice helps prevent and in some cases Reverse cognitive decline.
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Nature | Yu Jie et al. Reveal the composition of AMPAR complex in the hippocampus and the inhibitory mechanism of specific antagonists
Time of Update: 2021-05-21
The research team used single-molecule fluorescence imaging technology, electrophysiological experiments and cryo-electron microscopy to reveal for the first time the composition of the AMPAR complex in the hippocampus, the composition of accessory proteins, and the inhibitory mechanism of specific antagonists.
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Circulation: Prevent dementia?
Time of Update: 2021-05-21
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1"> heart blood vessels results of an observational study of risk factors (CVRF) focused on middle-aged people, but only a few studies from early adulthood begins.
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Stroke: Capsaicin's influence on cerebral perfusion and safety analysis
Time of Update: 2021-05-21
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels published a research article on the disease areas prestigious journal Stroke, the study sought to determine the safety and increase the dose of capsaicin effect on cerebral blood flow continuity transcranial Doppler measurement.
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Express | To benefit more stroke patients, Bojian capsule gets a new generation of thrombolytic therapy
Time of Update: 2021-05-21
Alfred Sandrock, head of research and development of Bojian Company, said that in the past 25 years, no new thrombolytic drug has been approved for the treatment of acute ischemic stroke.
Reference: [1] Biogen Announces Exercise of Option to Acquire the Investigational Drug TMS-007 for Acute Ischemic Stroke Based on Positive Phase 2a Data.
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China Session (2): Li Jun from Peking University Reveals Abnormal Migration of Intermediate Neurons in the Developmental Stage Induces Autism
Time of Update: 2021-05-21
On May 7, 2021, the research team of Li Jun/Zhang Dai from Peking University Sixth Hospital published an article in Nature, revealing the mechanism of autism-like behavior disorder caused by TRIO, a high-risk factor for autism, by regulating the migration of mesenteric neurons during embryonic development.
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JAMA Network: Hospital lights and noise are the two biggest culprits for children’s lack of sleep
Time of Update: 2021-05-21
Recently by the University of Toronto researchers , published in JAMA Network item on the study analyzed the hospitalized children sleep time and wake up at night with the relevant factors.
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Epilepsia: Physical training can improve executive function in adult patients with epilepsy
Time of Update: 2021-05-21
After the baseline and 12 weeks of intervention, record the subjects’ sociodemographic characteristics, clinical information, memory (digital span test [DST]), executive function (cue making test [TMT] A and B), Stroop color and word test, Speech fluency tasks, overall cognitive function (Montreal Cognitive Assessment [MoCA]), anthropometric measurements (weight, height, hip and waist circumference), cardiopulmonary function (maximum oxygen consumption [VO2 max]), and strength (dynamometer) ).
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J Stroke Cerebrovasc Dis: Robot rehabilitation training combined with VR technology can significantly improve the cognition and behavior of patients with chronic stroke
Time of Update: 2021-05-21
Recently, a randomized controlled clinical trial evaluated the impact of robotic neurorehabilitation with and without VR on the cognitive function and mental health of stroke patients compared with traditional therapies.
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Circulation | The evidence is here: to prevent secondary stroke, which one is better than monoclonal antibody and dual antibody?
Time of Update: 2021-05-21
It can be seen that compared with single-agent therapy, the dual-antibody therapy of aspirin plus clopidogrel with a treatment time of 30 days reduces the risk of stroke recurrence and compound events, and does not increase the risk of major bleeding.
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"Nature Communications" publishes the research results of the Center for Brain Excellence on the loop mechanism of motor planning
Time of Update: 2021-05-21
This research analyzes the loop function from the secondary motor cortex to the upper colliculus, reveals its key role in decision-related motion planning and its information processing mechanism.
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JAMA: The average age of onset of diabetes is actually related to the risk of dementia!
Time of Update: 2021-05-21
A review published in the Cochrane System last year did not find any strong evidence that specific treatments or treatment strategies for type 2 diabetes can prevent or delay cognitive impairment after including 13,934 participants in 7 randomized controlled trials.
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Epilepsy Behav: Ear acupuncture can effectively and safely treat mental non-epileptic seizures
Time of Update: 2021-05-21
The secondary result is to determine whether ear acupuncture can effectively reduce the frequency of PNES events.
gov/32759074/" target="_blank" rel="noopener">Auricular acupuncture for the treatment of nonepileptic seizures: A pilot study .
gov/32759074/" target="_blank" rel="noopener">Auricular acupuncture for the treatment of nonepileptic seizures : A pilot study in this message
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The correlation between new antiepileptic drugs and drug-induced liver injury: a real-world study from the FDA's adverse event reporting system
Time of Update: 2021-05-21
2% were "serious" reactions: death (262) disability (26) hospitalization (1,232) life-threatening reactions (248) congenital abnormalities or birth defects (4) And other serious reactions (1,475) ➤ Anti-epileptic drugs such as carbamazepine, phenobarbital, oxcarbazepine, phenytoin, valproic acid, lamotrigine, clobazan, levetiracetam, and diazepam, The incidence of drug-induced liver injury is higher than that of non-antiepileptic drugs (see Table 1).
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J Neurol Neurosurg Psychiatry: Laxam can be effective and safe as an adjuvant therapy for primary tonic-clonic seizures
Time of Update: 2021-05-21
The treatment of primary generalized tonic-clonic seizures (PGTCS) in IGE patients is very complicated.
This phase 3, double-blind, placebo-controlled trial (SP0982; NCT02408523) evaluated the effectiveness and safety of Laxam as an adjuvant therapy for PGTCS in IGE patients (≥4 years old).
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Neurology: Women with migraine have a significantly increased risk of high blood pressure during menopause
Time of Update: 2021-05-21
Migraine is related to the increased risk of high blood pressure in menopausal women.
0000000000011986" target="_blank" rel="noopener">Association of Migraine With Incident Hypertension After Menopause: A Longitudinal Cohort Study neurology.
0000000000011986" target="_blank" rel="noopener">Association of Migraine With Incident Hypertension After Menopause: A Longitudinal Cohort Study neurology.
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Research reveals the molecular mechanism of axon-enriched long non-coding RNA regulating axon growth
Time of Update: 2021-05-21
Recently, Cell Reports published online the latest research progress of the researcher Bao Lan's group at the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences-Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation.
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What do you know about autosomal recessive cerebellar ataxia?
Time of Update: 2021-05-21
Typical ataxia manifestations are as follows: Ataxia (appendicular or axial) of the limbs or trunk, Dysmetria, poor coordination, Dyssynergia, rotation dyskinesia, Dysdiadochokinesia, rebound phenomenon, Rebound Phenomenon, Dysarthria, Tremor, postural and gait instability, Titubation and increased postural sway tension reduction Hypotonia weakness Asthenia nystagmus Nystagmus and other eye movement disorders autosomal recessive inherited cerebellar ataxia (ARCA) is a complex, heterogeneous and disabling neurogenetic degeneration Diseases are more common in children and early adult patients.
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Does cerebral hemorrhage increase the risk of arterial ischemic events?
Time of Update: 2021-05-21
Therefore, it is not clear whether cerebral hemorrhage increases the risk of subsequent myocardial infarction and ischemic stroke.
Yimaitong compiled from: Association Between Intracerebral Hemorrhage and Subsequent Arterial Ischemic Events in Participants From 4 Population-Based Cohort Studies.
