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J Neurol Neurosurg Psychiatry: Laxam can be effective and safe as an adjuvant therapy for primary tonic-clonic seizures

 Last Update: 2021-05-21
 Source: Internet
 Author: User

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Idiopathic systemicmedsci.

medsci.

The study included 242 patients with IGE and PGTCS taking 1-3 anti-epileptic drugs at the same time.

The patients were randomly assigned and received ≥1 dose of the trial drug (lacosamide/placebo: n=121/n=121).

During the 24-week treatment period, the second PGTCS risk of lacosamide was significantly lower than that of placebo (Kaplan-Meier survival estimate was 55.

In summary, the results of the study show that Laxam is effective and safe as an adjuvant treatment for uncontrolled PGTCS in IGE patients.

Original source:

David G Vossler, et al.

ncbi.
nlm.
nih.
gov/32817358/" target="_blank" rel="noopener">Efficacy and safety of adjunctive lacosamide in the treatment of primary generalised tonic-clonic seizures: a double-blind, randomised, placebo-controlled trial in this message

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