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Alz Res Therapy: p-tau 181 can predict cortical atrophy
Time of Update: 2021-12-26
The important significance of this study lies in the discovery that higher plasma pTau181 levels are associated with neurodegeneration and predict aging and further brain atrophy in Alzheimer's disease .
Higher plasma pTau181 levels are associated with neurodegeneration and predict aging and further brain atrophy in Alzheimer's disease .
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Lancet Sub-Journal: Attention, pregnant mothers-not only will depression after delivery, but also increase the incidence of other mental disorders!
Time of Update: 2021-12-26
Women with first-onset postpartum mental disorder have similar PRSs to women with bipolar disorder and schizophrenia, and they are both significantly higher than those in the control group .
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Stroke: Machine learning yyds can accurately identify the occlusion of large vessels in stroke patients!
Time of Update: 2021-12-26
MSU's pre-hospital automatic large vessel occlusion (LVO) test can accelerate the identification and treatment of patients with acute ischemic stroke with LVO .
MSU's pre-hospital automatic large vessel occlusion (LVO) test can accelerate the identification and treatment of patients with acute ischemic stroke with LVO .
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Neurology: Is intravenous thrombolysis possible for unruptured aneurysms?
Time of Update: 2021-12-26
We evaluated the imaging reports and records of the Finnish healthcare registry and identified UIAs patients among all AIS patients receiving IVT treatment .
We evaluated the imaging reports and records of the Finnish healthcare registry and identified UIAs patients among all AIS patients receiving IVT treatment .
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Front.aging neurosci-Alzheimer's disease mouse model hippocampal CA1 N-methyl-D-aspartate receptor functional defect and synaptic plasticity
Time of Update: 2021-12-26
In addition, the morphological complexity and dendritic spines of mouse pyramidal neurons are reduced, and the expression levels of N-methyl-D-aspartate receptor subunits and related synaptic proteins in the hippocampus are reduced .
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Alzheimer Dementia: People who are wandering and helpless have a higher risk of dementia
Time of Update: 2021-12-26
It is estimated that 7% of veterans suffer from Alzheimer's disease (AD) and AD-related dementia (AD/ADRD) . Veterans suffering from traumatic brain injury and post-traumatic stress disorder have a h
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Stroke: Unexpectedly!
Time of Update: 2021-12-26
In summary, the long-term mortality rate of children after ischemic stroke has increased, and even after 20 years, neurological diseases are the most common cause of death .
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Alzheimer Dementia strengthens blood pressure, may reduce dementia-related pathological indicators
Time of Update: 2021-12-26
They studied the effects of enhanced (<120 mmHg) and standard (<140 mmHg) blood pressure control on the longitudinal changes of plasma amyloid β(Aβ)40 and Aβ42, total tau and neurofilament light chain (NfL), These participants were from a subgroup of the systolic blood pressure intervention trial (N = 517) .
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Alzheimer Dementia: Four thousand people, 20 years of follow-up found that: cognitive function is low, increasing the risk of death
Time of Update: 2021-12-26
Effect of cognitive impairment on risk of death in Hispanic/Latino adults over the age of 50 residing in the United States with and without diabetes: Data from the Health and Retirement Study 1995–2014.
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Alzheimer Dementia: Using medical record information may predict the risk of dementia in the future
Time of Update: 2021-12-26
They will participate in the clinical diagnosis of Alzheimer's disease (AD) and all-cause dementia in outpatient operations, inpatients, medical insurance administrative records and death certificates with the Catch County Memory, Health and Aging Study (CCSMHA) The study diagnoses of the authors were compared (1995-2008, N=5092) .
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Neurology: Dermatomyositis: The underlying pathobiological mechanisms of the potential subtypes of different antibody classifications are different
Time of Update: 2021-12-26
consensusInterestingly, DMSA-related clinical phenotypes have been characterized, including: anti-TIF1-γ DM with diabetic skin lesions, dysphagia, and malignant tumors; anti-Mi-2 DM with high creatine kinase (CK), myalgia, muscle Weakness ; anti-MDA5 DM with manipulators and interstitial lung disease (ILD), but low CK levels and less muscle involvement; anti-NXP-2 DM with muscle weakness but less skin involvement .
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Stroke: Stroke at a young age?
Time of Update: 2021-12-26
In order to comprehensively evaluate the causes of stroke in young patients and compare their results after endovascular thrombectomy with elderly patients, experts from the Department of Neurology of the University of Amsterdam in the Netherlands conducted a related study and the results were published in the journal Stroke .
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Stroke: What is the Eat-Lancet diet that is good for stroke prevention?
Time of Update: 2021-12-26
Secondary prevention strategies for ischemic stroke include antithrombotic therapy, lipid-lowering therapy, blood pressure management, and blood sugar management, which are essential for reducing stroke recurrence Important .
Secondary prevention strategies for ischemic stroke include antithrombotic therapy, lipid-lowering therapy, blood pressure management, and blood sugar management, which are essential to reduce stroke recurrence .
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JAMA Sub-Journal: It's amazing, the peripheral white blood cell count can predict the risk of depression!
Time of Update: 2021-12-26
In order to describe the relationship between the polygenic score of depression and inflammatory biomarkers (ie white blood cell count), experts from the Icahn School of Medicine at Mount Sinai, Massachusetts General Hospital, Cambridge and other universities and institutions conducted genetic association studies, and the results were published In JAMA Psychiatry magazine .
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Neurology: Adolescents who get fatter have a higher risk of multiple sclerosis!
Time of Update: 2021-12-26
In order to prospectively investigate the long-term relationship between the body mass index (BMI) of adolescents and young adults and the risk of multiple sclerosis (MS) at the population level, experts from the Department of Neurology of Haukeland University Hospital in Norway conducted related research.
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Stroke: New advances in neurocardiology
Time of Update: 2021-12-26
The LOOP study (Implantable Loop Recorder Detection of Atrial Fibrillation to Prevent Stroke) trial randomly divided patients 70-90 years old without atrial fibrillation and at least one risk factor for stroke into the ILR group and the conventional treatment group .
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Stroke: Gender differences in clinical manifestations of stroke
Time of Update: 2021-12-26
There may be substantial differences between the non-focal and focal stroke symptoms of acute stroke or transient ischemic attack in men and women, but there is a lack of sufficient high-quality research .
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JAMA Neurology: Patients with mechanical thrombectomy can also choose plain CT scans over time window
Time of Update: 2021-12-26
compared the clinical efficacy of non-enhanced CT (CT) and CT perfusion (CTP) or MRI (MRI) in patients with mechanical thrombus removal within an extended time window.
compared the clinical efficacy of non-enhanced CT (CT) and CT perfusion (CTP) or MRI (MRI) in patients with mechanical thrombus removal within an extended time window.
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Alzheimer Dementia: PDGFRβ is related to biomarkers of Alzheimer's disease
Time of Update: 2021-12-26
In addition, the concentration of CSF PDGFRβ increased in MCI patients (defined as a clinical dementia score [CDR] of 0.
Compared with the (AT-[N-]) control group, the PDGFRβ levels of aMCI/AD patients with AD+ biomarker characteristics increased (P = .
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Alzheimer Dementia: Beijing Aging Mental Recovery Action-How to carry out early prevention of cognitive impairment?
Time of Update: 2021-12-26
Recent studies have shown that Alzheimer's disease (AD) is the most common dementia, and its pathological basis can be detected as early as 20 years before the appearance of obvious clinical symptoms .
Early prevention of cognitive impairment in the community population: The Beijing Aging Brain Rejuvenation Initiative.
