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Neurology: Adolescents who get fatter have a higher risk of multiple sclerosis!

 Last Update: 2021-12-26
 Source: Internet
 Author: User

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Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelination of white matter in the central nervous system
.

The most commonly affected parts of the disease are periventricular white matter, optic nerve, spinal cord, brain stem and cerebellum.

The main clinical features of

The researchers used data from the Norwegian population-based mandatory tuberculosis screening program from 1963 to 1975 , including objectively measured height and weight of all eligible citizens ≈85%
.

This is combined with data from the Norwegian Multiple Sclerosis Registry and Biobank until November 2020

Screening

The results showed that during a follow-up of 30,829,506 person-years, 1409 cases of MS were found among 648,734 participants in the eligible age group (14-34 years old)
.

In general , obesity is associated with a 53% increase in the risk of multiple sclerosis (HR=1.

Obesity is associated with a 53% increase in the risk of multiple sclerosis (HR=1.

At the same time, the youngest age group has the highest risk (14-16 years old: HR = 1.
73 [95% CI 1.
19-2.
53]; 17-19 years old: HR = 1.
61 [95% CI 1.
08-2.
39]; 20-24 years old: HR = 1.
56 [95% CI 1.
04-2.
36]) At the same time, the youngest age group has the highest risk (14-16 years old: HR = 1.
73 [95% CI 1.
19-2.
53]; 17-19 years old: HR = 1.
61 [95% CI 1.
08-2.
39]; 20-24 years old: HR = 1.
56 [95% CI 1.
04-2.
36])

In summary, high BMI in individuals between 14 and 24 years of age is associated with an increased risk of multiple sclerosis in men and women in the future
.

In summary, high BMI in individuals between 14 and 24 years of age is associated with an increased risk of multiple sclerosis in men and women in the future

references:

Association of Body Mass Index in Adolescence and Young Adulthood and Long-term Risk of Multiple Sclerosis.

Association of Body Mass Index in Adolescence and Young Adulthood and Long-term Risk of Multiple Sclerosis.
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