-
A near-infrared activatable biomimetic nanogel drug delivery system ARNGs@TMZ/ICG
Time of Update: 2022-11-25
The collaborative team of Professor Luo Liang from the School of Life Science and Technology of Huazhong University of Science and Technology, Professor Shi Bingyang and Professor Zou Yan from the Co
-
Wonderful! Engineered prosthetics that target "glutamine addiction" in cancer cells so that healthy cells are not harmed
Time of Update: 2022-11-25
backgroundThe rapid growth of tumor cells requires a lot of energy, a lot of substrate for the synthesis of proteins and nucleic acids. Since glutamine can act as an energy source through the tricarb
-
Immunotherapy recruits: blocking the KIR2DL5/PVR immunosuppressive pathway to trigger NK cell-mediated anti-tumor immunity
Time of Update: 2022-11-25
Instead of summoning T cells to fight cancer, the Einstein School of Medicine research team looked at different human immune cells known as natural killer cells (NK), and achieved promising results 。 "We believe that the novel immunotherapies we have developed have great potential to enter clinical trials involving various types of cancer," said Xingxing Zang, Ph. D.
-
Nat Commun Yang Caiguang's research group at the Shanghai Institute of Materia Medica, discovered a new antibiotic that selectively agitates SaClpP
Time of Update: 2022-11-25
Original link: Small molecule selective agitation of Staphylococcus aureus ClpP against drug-resistant bacterial infections (Contributed by: Yang Caiguang Research Group) ClpP is a highly conserved ATP-dependent serine hydrolase in prokaryotes and eukaryotes responsible for regulating protein homeostasis.
-
The Cotton Genetic Improvement Team transfers two cotton biotechnology patents
Time of Update: 2022-11-25
Reviewed by Zhang Xianlong Nanhu News Network News (correspondent Jin Shuangxia) Recently, the cotton genetic improvement team of our school transferred two patents to Wuhan Tianwen Biotechnology Company at a price of 800,000 yuan, authorizing the company to carry out cotton genetic transformation and gene editing commercial services.
-
"Potato Road Difficulty"—South China Botanical Garden has made an important breakthrough in the analysis of the genetic basis of sweet potato insect resistance
Time of Update: 2022-11-25
In recent years, researcher Hou Xingliang of South China Botanical Garden of the Chinese Academy of Sciences has led the research team of plant development and quality regulation to focus on the genetic basis and efficient precision breeding technology of sweet potato.
-
Chengdu Biotechnology Institute has made important progress in palladium-catalyzed asymmetric carbonylation research
Time of Update: 2022-11-25
8;font-family:;font-size:12pt;} Palladium-catalyzed carbonylation is an important reaction widely concerned by academia and industry, and has a wide range of applications in the construction of a variety of practical molecules, through the introduction of carbon monoxide (carbonylation process), bulk chemical raw materials, such as olefins, alkyl or aryl halide compounds, can be converted into high-value products such as aldehydes, alcohols and carboxylic acid derivatives.
-
Surprise! Dying cancer cells also leave "last words" to neighboring tumor cells to instruct how to survive!?
Time of Update: 2022-11-25
Although cancer research in recent years has been able to significantly improve early diagnosis and treatment, resistance to conventional chemotherapy for advanced colorectal tumors remains a major problem and largely contributes to the high mortality rate of patients with such tumors.
-
Fudan University Science published an article to break the traditional cognition: the mystery of human oocyte spindle assembly
Time of Update: 2022-11-25
The correct assembly of the spindle is a key event for the smooth progress of mammalian mitomy classification and meiosis, and only the precise assembly of the spindle can ensure the correct separati
-
The latest results of Professor Wang Xinbing of Shanghai Jiaotong University were released at the UNESCO DDE Forum
Time of Update: 2022-11-25
On November 9, Professor Wang Xinbing's research group from the Department of Electronic Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, made
-
The Chengdu Institute has made new progress in the strategy of nitrogen nutrient acquisition in the rhizosphere of alpine coniferous forests
Time of Update: 2022-11-25
. TRS_Editor P{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_Editor DIV{margin-top:0px;margin-bottom:12px;line-height:1. 8;font-family:;font-size:12pt;}. TRS_E
-
The research group of Chen Lei of the School of Future Technology revealed the inhibition mechanism of the human glucose transporter SGLT1
Time of Update: 2022-11-25
Sodium-glucose co-transporter (SGLT) is an important transporter responsible for glucose reabsorption in the human body, enabling the reverse concentration gradient transport of glucose using the ele
-
The researchers unraveled patterns of gene activity in ADHD
Time of Update: 2022-11-25
Image credit: NHGRI's Darry LejaResearchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).
-
Xu Shuhua's team analyzed the adaptive evolution of vitamin B1 metabolism genes in East Asian populations
Time of Update: 2022-11-25
The study analyzed 3823 whole genomes of the global population, combined with ancient DNA data, and found vitamin B1 The genes involved in metabolic pathways are subject to specific positive natural selection in East Asian populations; This study further identifies the origin of adaptive haplotypes in East Asian populations, and estimates the timing and potential evolutionary drivers of specific natural selection in East Asian populations.
-
Nature: Immunomicroenvironment subtypes and neutrophil heterogeneity in liver cancer
Time of Update: 2022-11-25
++The results suggest that the intervention strategy targeting tumor-associated neutrophils can significantly improve the efficacy of immunotherapy in patients with liver cancer, thereby providing experimental evidence for the analysis of the heterogeneity of the immune microenvironment of liver cancer and providing a theoretical basis for the implementation of immunoprecision therapy for liver cancer.
-
Environmental DNA successfully captures marine biodiversity
Time of Update: 2022-11-25
"What do we need to know to use eDNA in coastal oceans, and can we make it work well in important urban environments?" These questions prompted us to undertake this study," said Regina Wetzer, curator and director of the Center for Marine Biodiversity at the Los Angeles County Museum of Natural History (NHM).
-
A new technique for culturing printed tissues for transplantation
Time of Update: 2022-11-25
Researchers at the Technion have developed an innovative technique to grow transplanted tissue by printing it into a microgel bath as a support material.
Researchers at the Technion have developed an innovative technique to grow transplanted tissue by printing it into a microgel bath as a support material.
-
Nonclassical receptor mechanisms by estrogen regulation of pain perception and opioid analgesia and itching
Time of Update: 2022-11-25
+In 2021, Rong Weifang's research group and Shi Xueyin's team published a collaborative paper in the Journal of Neurosciece, reporting the mechanism of GPER at the RVM site inhibiting itching by mediating opioid receptor phosphorylation.
-
Why Alzheimer's disease damages certain parts of the brain
Time of Update: 2022-11-25
Researchers at Washington University School of Medicine in St. Louis believe the similarities between the two sets of maps suggest that APOE played a role in making certain brain regions particularly vulnerable to Alzheimer's disease.
-
Scientists have discovered new antibiotics that kill dangerously resistant bacteria
Time of Update: 2022-11-25
”Reference: The researchers discovered the new antibiotic, Dynobactin, through a computational screening method.
”Just last year, Hiller's team deciphered the mode of action of the recently discovered peptide antibiotic Darobactin.
”Just last year, Hiller's team deciphered the mode of action of the recently discovered peptide antibiotic Darobactin.
