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Targets cancer cells' appetite for glutamine and keeps healthy cells from harm
Time of Update: 2022-11-25
Figure: Schematic showing the biological activation of DON by DRP-104 in tumors and the biological inactivation of an inert metabolite in GI tissues. Photo by Jennifer E. Fairman, CMIResearchers at J
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Why does Alzheimer's disease damage certain parts of the brain?
Time of Update: 2022-11-25
Gordon, who is also an assistant professor of psychology and brain science, said: "Where you see high APOE expression, where you see tau protein tangles and tissue damage, there's a close match between the two.
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Qinghai Key Laboratory of Cold Region Restoration Ecology has made progress in the study of the relationship between species diversity and productivity on long-term simulated warming responses in alpine meadows
Time of Update: 2022-11-25
The research team of Qinghai Key Laboratory of Cold Region Restoration Ecology of the Northwest Institute of Plateau Biology, Chinese Academy of Sciences took the alpine dwarf grass meadow as the research object, and carried out the response of species diversity and productivity to long-term simulated warming from the community level and functional group level.
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Synthetic biology meets medicine: "programmable molecular scissors" may help fight COVID-19 infection
Time of Update: 2022-11-25
Scientists at the University of Cambridge have used synthetic biology to create artificial enzymes that target the genetic code of SARS-CoV-2 and destroy viruses, a method that could be used to develop a new generation of antiviral drugs.
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How to suppress harmful immune responses?
Time of Update: 2022-11-25
Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
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Chinese Academy of Sciences scholar Cell published an article showing how fentanyl and morphine act on μ opioid receptors
Time of Update: 2022-11-25
041Molecular recognition of morphine and fentanyl by the human μ-opioid receptor Pain, especially chronic pain, is a common neurological phenomenon.
041Molecular recognition of morphine and fentanyl by the human μ-opioid receptor Pain, especially chronic pain, is a common neurological phenomenon.
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The researchers identified changes in blood proteins two years before breast cancer diagnosis
Time of Update: 2022-11-25
Ms Hagenaars said: "These proteins can be used as the basis for blood tests for the early detection of breast cancer in high-risk women.
Ms Hagenaars said: "These proteins can be used as the basis for blood tests for the early detection of breast cancer in high-risk women.
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Class 1 new drug PA9159 inhaled aerosol for asthma indication was approved for clinical trials
Time of Update: 2022-11-25
Structural diagram of GR combined with DAC and DEX Based on the deep understanding of the high-definition structure of GR and drug interaction, Xu Huaqiang's research group synthesized a large number of lead compounds in more than ten years of continuous exploration, and further in-depth research on the efficacy and side effects of compounds, and finally found the ideal compound PA9159 with high efficacy and low toxic side effects.
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The Academy of Plant Sciences and the Academy of Economics and Management held an interdisciplinary strategic consultation seminar
Time of Update: 2022-11-25
The scene of the meeting (Photo by correspondent Wang Min) On the afternoon of November 15, the strategic consulting seminar jointly held by the College of Plant Science and Technology and the School
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Where humans live, microplastics end up in rivers
Time of Update: 2022-11-25
A research team led by Dr. Jason Knuft, professor of biology, principal investigator of the SLU WATER Institute, and scientist at the National Center for Great Rivers Research and Education, and Dr. Elizabeth Hasenmuller, associate professor of earth and atmospheric sciences and associate director of the SLU WATER Institute, studied microplastic levels at 19 sites along the Meramek River, including downstream large cities and less populated rural areas.
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Irradiating only a portion of the lymph nodes significantly reduces the recurrence of several cancers
Time of Update: 2022-11-25
A promising new study released by the University of Colorado Cancer Center shows that recurrence of certain cancers can be significantly reduced by irradiating only a group of lymph nodes near a tumor, rather than all of them.
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Nerve cells have become accomplices of oral cancer!
Time of Update: 2022-11-25
”Indeed, cohort analysis by Tong and his colleagues of human OSCC patients and mouse models showed a high density of nociceptive nerves around tumors, and in vitro experiments showed that when tumors found themselves in a malnourished environment, tumors promoted peripheral nerve growth by secreting nerve growth factor (NGF), essentially surrounding the tumor with pain receptors.
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The latest results of Wang Huaimin's team from the School of Science of Westlake University appeared on the cover of Nano Letters to control the dynamics of peptide assembly, causing a "butterfly effect" in cells
Time of Update: 2022-11-25
cn Recently, the team of Wang Huaimin of the Department of Chemistry of Westlake University and the team of Huang Feihe of the Department of Chemistry of Zhejiang University published a report entitled "Controlling Intracellular Enzymatic Self-Assembly of Peptide by Host-Guest Complexation for Programming Cancer Cell Death" at Nano Letters ".
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Quantum biologists have found that enzymes may be the key to understanding DNA mutations
Time of Update: 2022-11-25
1038/s42004-022-00760-x According to a new study from the University of Surrey, enzymes that are essential for controlling the way human cells replicate may be precisely what encourages spontaneous mutations in DNA, leading to potentially permanent genetic errors.
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How the pattern of brain gene activity differs in individuals with ADHD
Time of Update: 2022-11-25
Researchers at the National Institutes of Health (NIH) have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).
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Mol Cell Shanghai Institute of Medicine cooperated to discover a novel mechanism of action of the cellular energy receptor AMPKγ
Time of Update: 2022-11-25
On November 15, 2022, the team of Professor Zhao Bin and Professor Feng Xinhua of the Institute of Life Sciences of Zhejiang University, and the team of Tan Minjia, a researcher at the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, published an online report entitled Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of Molecular Cell Research paper by AMPK alpha.
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Science: Uncovering a molecular mechanism by which non-coding single nucleotide polymorphisms drive human gliomagenesis
Time of Update: 2022-11-15
abj2890 Scientists from Mount Sinai Hospital and other institutions have identified important clues for the prevention and treatment of human gliomas through research, and the relevant research results may provide new ideas and perspectives for revealing the biological changes behind the occurrence of gliomas.
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Professor Zhang Tiejun of our institute and researcher Xingdong Chen of the Institute of Human Phenomics teamed up to discover new clues about the association between alcohol consumption and hepatocellular carcinoma
Time of Update: 2022-11-15
The proportion of different subgroups who mainly drink wine The results of this study suggest that low- to moderate alcohol consumption may be inversely associated with the risk of HCC in people at low risk of liver cancer, which may be largely related to wine consumption.
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High-throughput computational microscopy imaging
Time of Update: 2022-11-15
Image: The hybrid light-dark field transfer intensity (HBDTI) method for high-throughput quantitative phase microscopy significantly extends the spatial bandwidth product of conventional microscopes and expands the accessible sample spatial frequencies in Fourier space far beyond the traditional coherent diffraction limits.
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The team of Professor Bi Guoqiang of the University of Science and Technology of China/Shenzhen Advanced Institute of the Chinese Academy of Sciences has made an important breakthrough in the development of cryo-EM in situ imaging technology
Time of Update: 2022-11-15
The team of Bi Guoqiang, a dual-appointed professor from the University of Science and Technology of China and the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences, cooper
