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Intravenous experimental cancer vaccine found significant tumor regression
Time of Update: 2022-11-26
References:Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment The scientists found that intravenous vaccines increased the number of cytotoxic T cells capable of penetrating and attacking tumor cells and involved the innate immune system by inducing type I interferon.
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Do you think children learn faster than adults? A paper proves you right
Time of Update: 2022-11-26
Article Efficient learning in children with rapid GABA boosting during and after training Figure: Changes in GABA in the brains of children and adultsIf you've ever felt like your elementary school child is "smarter" than you, or at least quicker to acquire new information and skills, a new study in contemporary biology suggests you're absolutely right.
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Nature: New statistical methods improve genomic analysis
Time of Update: 2022-11-26
CLIMB: High-dimensional association detection in large scale genomic dataA new statistical approach provides a more efficient way to reveal biologically meaningful changes in genomic data that span multiple conditions—such as cell type or tissue.
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Nature: Anti-cancer drugs are approaching some of the deadliest mutations
Time of Update: 2022-11-26
While the approval of sotorasib was a milestone, the drug targeted only one specific mutation of the KRAS protein, and its effects were short-lived: Most people who initially responded relapsed months later.
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The new role of the coagulation protein VWF in triggering inflammation
Time of Update: 2022-11-26
Research from the RCSI University of Medicine and Health Sciences found a new role in coagulation protein: von Willebrand factor (VWF), which plays an important role in regulating the immune response at the site of vascular injury.
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Decoding secretor-mediated neuron-immune cell interaction networks
Time of Update: 2022-11-26
Recently, Lu Yao's team, a researcher in the single-cell analysis research group of the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, used single-cell multi-secreted factor detection technology to realize the analysis of neuro-immune cell interaction networks.
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eLife: How do we feel the pain of others?
Time of Update: 2022-11-26
A new study from the Netherlands Institute for Neuroscience documents neurons in human patients, showing that the pain of others is mapped directly to neurons in the insulus, an area of the brain tha
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Mast cell levels may explain the sex difference in osteoarthritis pain
Time of Update: 2022-11-26
Researchers at the Hospital for Special Surgery (HSS) found that during total knee replacement, women had significantly higher levels of immune cells called mast cells in synovial tissue around the knee than in men.
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Scientists have discovered new variants in sperm cells
Time of Update: 2022-11-26
Article Mutagenesis alters sperm swimming velocity in Astyanax cave fish Image: Male Mexican blind hole fish (Blind hole fish)Photo credit: Richard Borowsky, New York UniversityA team of scientists has found that the behavior of sperm cells is due in part to the individual DNA makeup of those cells, not just to the genes of men.
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Nature Medicine: MSKCC Releases Blockbuster Results of Liquid Biopsy for Lung Cancer! Large international cohorts confirmed that ctDNA is effective in predicting non-trivial prognosis and guiding targeted therapy
Time of Update: 2022-11-26
[4] [5] In recent years, the treatment and prognosis of patients with non-small cell lung cancer (NSCLC) have greatly improved thanks to targeted therapy, which is mainly based on the wide application of tissue sequencing, but in the real world, there are many patients who cannot perform tissue sequencing for various reasons [1-3], so it is easier to obtain samples and detect blood circulating tumor DNA (ctDNA) "homeopathic".
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A high-fat diet can induce pain sensitivity
Time of Update: 2022-11-26
A new study in mice conducted by researchers at the University of Texas at Dallas suggests that short-term exposure to a high-fat diet may be associated with pain sensations, even if there are no previous injuries or pre-existing conditions such as obesity or diabetes.
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Nanoparticle probiotic "backpack"
Time of Update: 2022-11-26
Reference: Mucoadhesive probiotic backpacks with ROS nanoscavengers enhance the bacteriotherapy for inflammatory bowel diseases This schematic diagram shows probiotics (blue-green) being wrapped in a layer of biomaterial as they pass through the human intestine.
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MIT has developed a new synthetic gene control system
Time of Update: 2022-11-26
Reference: A synthetic transcription platform for programmable gene expression in mammalian cells Researchers have developed a technique that can help fine-tune the production of monoclonal antibodies and other useful proteins.
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Use subtle electrical signals to detect and stop brain damage
Time of Update: 2022-11-26
The algorithm developed by Dr. Abbasi can accurately detect subtle EEG biomarkers identified by the team within the first 6 hours of HI brain injury occurring, which could be a game-changer for treating high-risk infants.
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The researchers came up with a new way to remove microplastics from water
Time of Update: 2022-11-26
Craig Arnold, the Susan Dod Brown Professor of Mechanical and Aerospace Engineering and associate dean of innovation at Princeton University, collaborates with his lab to create new materials, including aerogels, for engineering applications.
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Science: How melanoma maintains telomere length and achieves immortality
Time of Update: 2022-11-26
Original searchTPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma Overcoming death and moving towards immortality is a crucial step in the cell's march toward cancer.
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The relationship between seed functional traits and plant distribution area size revealed by Kunming plants (please refer to this manuscript)
Time of Update: 2022-11-26
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The rapeseed team and the bioinformatics team revealed the gene regulatory network for oilseed content in rapeseed
Time of Update: 2022-11-25
1186/s13059-022-02801-z Nanhu News Network News (Correspondent Tan Zengdong) On November 7, the rapeseed team of Huazhong Agricultural University and the bioinformatics team published a report entitled "Comprehensive transcriptional variability analysis reveals gene networks regulating seed oil content of Brassica napus" in Genome Biology Research papers.
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How does puberty begin to develop?
Time of Update: 2022-11-25
On November 17, 2022, Wu Qingfeng's team from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and the miserly team from the School of Life Sciences of Tsinghua University published an online report entitled " Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset".
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The latest article by Chinese scholar Nature determined the genetic mechanism of modern corn protein decline
Time of Update: 2022-11-25
On November 17, 2022, Beijing time, the research team of Wu Yongrui of the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences and the research team of Wang Wenqin of
