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Genomic studies have revealed a new branch of fungal evolution
Time of Update: 2023-01-05
0)Photo by Alan RockefellerA team led by the University of Alberta says about 600 distinctly different looking fungi have a common ancestor that never found a proper place in the fungal family tree.
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Nat Commun Shanghai Institute of Materia Medica: Jointly constructs a surface function biomimetic nanodrug carrier to improve the effect of oral insulin therapy
Time of Update: 2023-01-05
Construction of biomimetic viral nanocarriers with surface ligand conversion and in vivo delivery (Contributing department: Gan Yong Research Group; Contributor: Yang Tiantian) Diabetes is a chronic metabolic disease that seriously threatens human health.
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The heart-damaging SARS-CoV-2 protein has been found!
Time of Update: 2023-01-05
In addition, protein genes involved in glycolysis (the breakdown of glucose into usable energy) were upregulated in muscle heart cells or cardiomyocytes of Nsp6 fruit flies.
In addition, protein genes involved in glycolysis (the breakdown of glucose into usable energy) were upregulated in muscle heart cells or cardiomyocytes of Nsp6 fruit flies.
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A novel mechanism by which ARID2 regulates lipid homeostasis in the liver
Time of Update: 2023-01-05
1038/s41418-022-01090-0 On November 17, 2022, the international academic journal Cell Death & Differentiation published online the research results of Xie Dong's research group entitled "ARID2 mitigates hepatic steatosis via promoting the ubiquitination of JAK2" by the Xie Dong research group of the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences 。 This study reveals the important role of ARID2 in the development and development of NAFLD and provides a promising therapeutic strategy for NAFLD patients with ARID2 deficiency.
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Professor Huang Jia's research group from the College of Agriculture published a paper in Science Advances to reveal new targets for insecticides
Time of Update: 2023-01-05
Figure 1: Schematic diagram of the mechanism of action of flufenamide Through a series of experiments such as behavioral genetics, enzyme kinetics, and comparative pharmacology in Drosophila, the authors found that nicotinamide is specifically expressed in the chordal neuron of Drosophila, and the metabolite T FNA-AM of flufenamide in worms leads to the accumulation of the substrate nicotinamide by inhibiting nicotinase activity, thereby overactivating T RPV ion channels produce symptoms of toxicity (Figure 1).
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Yang Xiaodong's team from Suzhou Medical Institute proposed a design theory of high-uniformity multilayer Halbach magnet
Time of Update: 2023-01-05
In order to solve this problem, the desktop magnetic resonance spectroscopy group of Yang Xiaodong's research team of Suzhou Medical Institute constructed the optimization theory of multilayer Halabch magnets, and proved the middle edge z of multilayer Halbach array magnets The shaft inhomogeneity is the largest, and the multilayer Halbach magnet design and optimization model is established based on the derivation of the magnetic field distribution equation of the single-layer Halbach magnet.
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Aging Cell: Repetitive stress accelerates the aging of the eye
Time of Update: 2023-01-05
essayStress induced aging in mouse eye Pictured: When the UCI-led team studied the optic nerve head of the eye treated with mild pressure elevation, they noticed that in the young optic nerve head, there were no signs of axon loss.
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Feat—New study of 5 million people reveals a link between genes and height
Time of Update: 2023-01-05
" ”Reference: A saturated map of common genetic variants associated with human height The results of this study may help doctors identify patients who are unable to grow to the height they would expect, which in turn may help identify undiagnosed diseases or conditions that may hinder their normal growth or negatively affect their health.
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The Bao Lan group revealed the development and mechanism of m6A-modified long-encoded RNA regulating neuronal development
Time of Update: 2023-01-05
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Nature sub-journal: Measuring organ development
Time of Update: 2023-01-05
Jan Brugues, Frank Jülicher and Elly Tanaka, leaders of the study, concluded: "We hope that our findings will lead to new insights into the interactions between shape and network connections in complex tissue structures and organ development.
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How "history" shapes people's DNA
Time of Update: 2023-01-05
” Although health care and economic theories for pregnant women have evolved since the 2030s, Schmitz believes that studies like this can shed light on today's social problems.
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Repair the intestines after stroke and save brain function
Time of Update: 2023-01-05
The Texas A&M University team investigated a new idea of whether transplanting intestinal epithelial stem cells (IESCs) from healthy donors could repair the intestinal barrier after a stroke and improve stroke outcomes.
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Professor Huang Zhenlie's team from the School of Public Health has published the latest research results in international authoritative academic journals
Time of Update: 2023-01-05
Recently, the research results of Professor Huang Zhenlie's team on the health hazard effects of microplastics in the School of Public Health of our university have been published in the internationa
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Chinese scholars have discovered a new mechanism for maintaining hematopoietic stem cell homeostasis
Time of Update: 2023-01-05
Figure Schematic diagram of the key role mechanism of nutritional regulation of mTORC1 in hematopoietic stem cell homeostasis With the support of the National Natural Science Foundation of China (gra
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Prevent future influenza pandemics! Science's latest research develops mRNA influenza vaccines against all known subtypes
Time of Update: 2023-01-05
Researchers at the University of Pennsylvania's Perelman School of Medicine say that in initial tests, an experimental mRNA-based vaccine against all 20 known subtypes of influenza viruses offered broad protection against other deadly flu strains, so it could one day become a general preventive measure for future influenza pandemics.
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Nature of Sichuan University published an article on the development and verification of the whole process of clearance of mouse pancreatic tumors by a Pin1 inhibitor delivery system based on targeting CAFs
Time of Update: 2023-01-05
engagement。 In this study, a prolyl isomerase PIN1 inhibitor delivery system based on CAFs-targeted antibodies and DNA barcode bundle gel system was developed, which introduced CD8+ T cells into tumors with CD8+ T cell-specific aptamers, achieved pancreatic tumor clearance in in an in situ model of mouse pancreatic cancer, and realized the treatment of mouse pancreatic cancer by reshaping the tumor microenvironment.
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The Peng Fei team from the Department of Psychology of the School of Public Health published the latest research results in eLife
Time of Update: 2023-01-05
Recently, Professor Peng Fei's research group of the Department of Psychology of the School of Public Health published a research paper entitled "Bumblebees retrieve only the ordinal ranking of forag
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The Nature sub-journal breaks the conventional wisdom: superbugs in the environment rarely transmit to humans
Time of Update: 2023-01-05
Image source: University of BathAn international team of scientists investigating the spread of a deadly drug-resistant bacterium comparable to MRSA found that although the bacteria are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.
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Previous vaccines may not have enough antibodies? There is a growing trend of new omicron subvariants evading antibodies
Time of Update: 2023-01-05
"Studies produced by other labs on neutralizing antibodies to bivalent enhancers suggest that newer boosters will provide protection against new small particle subvariants, Liu said.
"Studies produced by other labs on neutralizing antibodies to bivalent enhancers suggest that newer boosters will provide protection against new small particle subvariants, Liu said.
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Relationship between acquired X chromosome silencing deviation and chronic diseases in middle and old age
Time of Update: 2023-01-05
Scientists at King's College London have a new understanding of how a process known as X chromosome inactivation shift (XCI-skew) affects an individual's later life, and they published their findings today in eLife.
