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The latest research challenges the role of "good" cholesterol in predicting heart disease risk in general
Time of Update: 2023-01-05
The study, published in the Journal of the American College of Cardiology, found that while low levels of HDL cholesterol predicted an increased risk of heart attack or related death in white adults, a long-accepted association, it was not true for black adults.
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A new sign of amyotrophic lateral sclerosis (ALS) reveals possible triggers for neurodegeneration
Time of Update: 2023-01-05
Corinne Houart, Professor of Developmental Neurobiology at King's College and lead author of the study, said: "Finding the same mRNA abnormalities in zebrafish SFPQ mutants and human ALS neurons opens up a new avenue for understanding neurodegenerative processes.
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ACS Chem Neurosci: New biomarkers could help scientists diagnose Alzheimer's disease as early as possible
Time of Update: 2023-01-05
Once, a definitive diagnosis of Alzheimer's disease was only possible after a patient's death, but recent biomarker studies may hopefully help researchers develop novel imaging and spinal fluid testi
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Cell Discovery: Jiao Jianwei's team revealed a new mechanism by which human-specific genes promote cerebral cortical folding
Time of Update: 2023-01-05
The study found that the human-derived gene SERPINA3 promoted the expansion and folding of the mouse cortex, increased the number of upper neurons, and significantly improved the cognitive ability of the mice.
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Precise genome editing of RBM20 pathogenic mutations may salvage dilated cardiomyopathy
Time of Update: 2023-01-05
The findings suggest that precise correction of gene mutations using precise gene editing methods (single-gene diseases) may be a promising approach for treating dilated cardiomyopathy.
The findings suggest that precise correction of gene mutations using precise gene editing methods (single-gene diseases) may be a promising approach for treating dilated cardiomyopathy.
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Nature Neuroscience's single-cell mass spectrometry flow cytometry reveals the development of the somatosensory system
Time of Update: 2023-01-05
The results collected by Deppmann and his colleagues provide new valuable insights into the maturation of somatosensory cells in DRG and their unique developmental stages.
The results collected by Deppmann and his colleagues provide new valuable insights into the maturation of somatosensory cells in DRG and their unique developmental stages.
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The drug triggers immune cells to attack prostate cancer
Time of Update: 2023-01-05
Image: According to new research from Washington University School of Medicine in St. Louis, a drug compound stimulates immune cells to attack prostate tumors.
Image credit: Nupam MahajanImage: According to new research from Washington University School of Medicine in St. Louis, a drug compound stimulates immune cells to attack prostate tumors.
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Mechanoregulation of the RNA-binding protein hnRNPC in a failed heart
Time of Update: 2023-01-05
Mechanical regulation helps clarify heart failuresummaryHeart disease is characterized by a strong remodeling of the extracellular matrix (ECM), which eventually leads to heart failure.
Mechanical regulation helps clarify heart failuresummaryHeart disease is characterized by a strong remodeling of the extracellular matrix (ECM), which eventually leads to heart failure.
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Nature: The magical "hollow sphere" protein protects the genome of cancer cells
Time of Update: 2023-01-05
MYC proteins also show a previously unknown activity that now opens new doors for cancer research: They form hollow spheres that protect particularly sensitive parts of the genome.
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Professor Gao Shuai of Wuhan University cooperated with Professor Yan Ning, and Cell released the latest collaborative research results of drug regulation of calcium ion channels
Time of Update: 2023-01-05
News Network News (Correspondent Yang Peng) On November 22, Professor Gao Shuai of the School of Pharmacy of Wuhan University and Yan Ning, former Professor of Princeton University, jointly published the latest research results of drug regulation of calcium ion channels online in Cell (Cell) magazine.
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The methyltransferase SMYD3 regulates a new function of hypoxic tolerance in the body
Time of Update: 2023-01-05
Recently, Xiao Wuhan's team from the Institute of Hydrobiology, Chinese Academy of Sciences revealed the mechanism by which methyltransferase SMYD3 inhibits hypoxic tolerance by activating the hypoxia signaling pathway, and this inhibitory function does not depend on the methyltransferase activity of SMYD3.
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Nature Genetics' world's largest research has found new Alzheimer's genes
Time of Update: 2023-01-05
The study, titled "Exome sequencing identifies rare disruptive variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease," was published in Nature Genetics.
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease
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The deubiquitinase USP7 is a novel cyclin F interaction protein that regulates the stability of cyclin F protein
Time of Update: 2023-01-05
A new research paper, published in the journal Aging, titled "Deubiquitinase USP7 is a novel cyclin F interacting protein and regulates cyclin F stability.
A new research paper, published in the journal Aging, titled "Deubiquitinase USP7 is a novel cyclin F interacting protein and regulates cyclin F stability.
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Luo Huan and Zhang Hang's research group published a paper in Progress in Neurobiology to reveal the dynamic emergence of relationship network structure in the human brain...
Time of Update: 2023-01-05
Emergence of higher-order structures in neural signaling and computational modelsIn summary, Luo Huan and Zhang Hang's research group combined behavioral, neural and computational models to reveal the neural mechanism and computer theory behind the human brain's extraction and learning from continuous picture streams, and then establishing the neural mechanism and computer theory of high-order statistical structure (intracluster compression and intercluster distance) from this low-order transfer probability.
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Challenging perception – "Good" cholesterol isn't necessarily good for everyone
Time of Update: 2023-01-05
One study found that high-density lipoprotein (HDL) cholesterol, often referred to as "good cholesterol," may not be as effective at predicting cardiovascular disease risk in adults of different racial and ethnic backgrounds as scientists once thought.
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Hou Tingjun's research group from the School of Pharmacy of Zhejiang University reported in Acta Pharmaceutica Sinica B based on Tushen...
Time of Update: 2023-01-05
75em;text-align:justify;margin-top:5px;margin-bottom:5px;" class="western"> The acid dissociation constant (pKa) is a key parameter reflecting the ionization ability of compounds, which determines the existence form of drugs in physiological environment, which in turn affects their absorption, distribution, metabolism, excretion and other pharmacokinetic properties in vivo, which has important guiding significance for the optimization of lead compounds.
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Zhao Li, a teacher at JI at Jiaotong University, proposed a unique self-charging mechanism applied to wearable devices in his research group
Time of Update: 2023-01-05
Recently, Zhao Li, assistant professor of the JI of Shanghai Jiao Tong University, published a report entitled Enhanced Spontaneous Self-Charging through Scalable Template-Free Surface Engineering at Building Block Fiber Scale in Nano Energy (impact factor of 19.
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The researchers identified brain markers for ADHD in children
Time of Update: 2023-01-05
The researchers analyzed MRI data from nearly 8,000 children and found biomarkers for attention-deficit/hyperactivity disorder (ADHD) and the possible role of neuroimaging machine learning in helping diagnose, plan and monitor the disorder.
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Using Nobel Prize-winning techniques, Nature's new research reveals a key protein mechanism involved in a wide range of cellular processes
Time of Update: 2023-01-05
Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes, which could pave the way for better, less toxic cancer drugs.
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PNAS: Where you live doesn't have as much impact as you think
Time of Update: 2023-01-05
essayImpact of cultural and genetic structure on food choices along the Silk Road Image: Figure 1.
essayImpact of cultural and genetic structure on food choices along the Silk Road Image: Figure 1.
essayImpact of cultural and genetic structure on food choices along the Silk Road Image: Figure 1.
