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Nature: Thanks to symbiotic bacteria, seaweed becomes a natural carbon dioxide absorption pool
Time of Update: 2021-11-14
Wiebke Mohr and her colleagues from the Max Planck Institute for Marine Microbiology in Bremen, Germany, the Hydra Institute for Marine Science in Bühl, Germany, and the Swiss Water Research Institute Eawag, and her colleagues now describe how this intimate relationship between seaweed and bacteria is.
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Bring 91% of patients back to normal triglycerides and innovative oligonucleotide therapy advances to phase 3 clinical trials
Time of Update: 2021-11-14
On November 2, 2021, Ionis Pharmaceuticals announced the initiation of a pivotal Phase 3 clinical trial of the antisense oligonucleotide (ASO) therapy olezarsen under development.
Reference materials:[1] Ionis initiates pivotal Phase 3 clinical study of olezarsen in patients with severe hypertriglyceridemia.
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Artificial intelligence technology reveals the secret of spider web weaving
Time of Update: 2021-11-14
Researchers at Johns Hopkins University used night vision and artificial intelligence to track every movement of the spider's eight legs while it was working, and accurately recorded how the spider weaves its web .
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Chen Jianhao's research group from the Quantum Materials Science Center of the School of Physics realizes the first electronically controlled two-dimensional magnon valve
Time of Update: 2021-11-14
In cooperation with Associate Professor Yu Peng of Sun Yat-Sen University, he established a two-dimensional magnon model and quantitatively analyzed the high nonlinearity in its transport process; using this nonlinearity, Chen Jianhao’s research group prepared a van der Waals antiferromagnetic The magnon valve of the insulator MnPS 3 (manganese phosphorous sulphur) realizes the completely reversible electric control of its second harmonic magnon signal, and demonstrates the diffusion type magnon logic NOT gate for the first time .
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Chinese scholars have made progress in the genetic mechanism of cerebrospinal cavernous malformation
Time of Update: 2021-11-14
Figure 1 Reveals the important genetic mechanism of sporadic cavernous malformations in the central nervous system (Brain cover article)
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Tumor targeting: inducing apoptosis of cancer cells in T-cell acute lymphoblastic leukemia
Time of Update: 2021-11-14
5Z7O selectively targets leukemia T cells in two T-ALL mouse models and xenogeneic cells transplanted from patients, and shows a synergistic effect when used in combination with the first-line therapeutic drug dexamethasone .
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Nature draws the goal in mind
Time of Update: 2021-11-14
"Our current work solves this problem and shows that the future goal behaves as a pattern of neural activity, similar to the pattern of previous visits to the target location (such as a supermarket) .
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New discovery: a core gene network that simultaneously controls pluripotency and cell death
Time of Update: 2021-11-14
""To clarify how the functions of human embryonic stem cells are controlled by genetics is essential for our understanding of developmental biology and regenerative medicine," said co-corresponding author Stephen Elledge, Ph. D.
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Oncolytic virus "guides" CAR-T therapy, cutting-edge partners join forces to explore new strategies for solid tumor treatment
Time of Update: 2021-11-14
On November 1, 2021, Imugene announced that it has reached a strategic cooperation agreement with Eureka Therapeutics to evaluate Imugene's CD19-expressing oncolytic virus, combined with Eureka's CD19-targeted T cell therapy, and treat entities Tumor potential .
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Chinese scholars have made progress in the research of atmospheric turbulence effect imaging degradation mechanism and degradation suppression
Time of Update: 2021-11-14
In response to this problem, Professor Bai Xiangzhi’s team conducted semi-physical simulations based on the imaging degradation mechanism of atmospheric turbulence effects, and proposed a reverse reasoning method based on generative countermeasure networks (TSR-WGAN), which suppressed the blurring effect caused by light fluctuations (Figure 2( a)), alleviating the continuous geometric distortion and jitter in the time domain caused by the change of the optical path (Figure 2(b)) .
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This antibody treatment prevents inflammation of the lungs and nervous system after SARS-CoV-2 infection
Time of Update: 2021-11-14
A new study by researchers at the University of California, Davis shows that monoclonal antibodies can protect elderly diabetic rhesus monkeys from diseases caused by SARS-CoV-2 and reduce the amount of cerebrospinal fluid Signs of inflammation inside .
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Cell Rep: Key genes for sperm production were discovered
Time of Update: 2021-11-14
"Learning more about the role of Cdc42 in the male reproductive system provides key information for using this gene as a potential biomarker for infertility or decreased testicular function," De Falco said .
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Chinese scholars and foreign collaborators have made progress in ancient human genome research
Time of Update: 2021-11-14
This research result has reshaped our understanding of the population evolution process in Xinjiang and Eurasian grasslands, and provided important genetic evidence for a more comprehensive and systematic restoration of the origin and evolutionary history of ancient humans.
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"Pick/Merge" antigen design: a new strategy for universal vaccine design without fear of variants
Time of Update: 2021-11-14
In order to solve this problem, Baseimmune's vaccine design algorithm integrates genomic, epidemiological, immunological, clinical and evolutionary data to create a new synthetic antigen, which contains all pathogens "most likely to elicit strong protective immunity.
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Chinese scholars and overseas collaborators have made progress in the field of dielectric energy storage
Time of Update: 2021-11-14
The research team proposes a new idea for designing energy storage dielectric materials in the superparaelectric state (T m ~ T B temperature region): temperature induction reduces the volume of the electrical domains in the relaxor ferroelectrics, weakens the coupling, and reduces the flipping energy barrier.
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Guangzhou Health Institute Cell Discovery issued a paper: Cultivating the world's first human permanent neonatal diabetic canine model
Time of Update: 2021-11-14
to use a single-base editor to perform point mutations on glucokinase, successfully cultivating the world’s first human permanent neonatal diabetic canine model.
Related papers " Generation of Permanent Neonatal Diabetes mellitus Dogs with glucokinase Point mutations Base editin through G" published online in Cell Discovery magazine .
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Three major "world premieres" appeared in the Expo, Varian embarks on a new journey of anti-cancer
Time of Update: 2021-11-14
Shanghai, November 2, 2021/PRNewswire/ - On November 2, 2021, the 4th China International Import Expo (hereinafter referred to as the "CIIE") will open soon, as the fourth consecutive CIIE participati
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Chinese scholars complete the high-efficiency total synthesis of natural drug paclitaxel
Time of Update: 2021-11-14
21971105), the team of Southern University of Science and Technology Li Chuangchuang efficiently and concisely completed the asymmetric total synthesis of the anti-cancer natural drug paclitaxel .
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Nature Sub-Journal: To further understand the structure of protein-sugar based on artificial intelligence model
Time of Update: 2021-11-14
Jon AgirreNew research based on artificial intelligence algorithms enables scientists to create more complete models of human protein structures, paving the way for faster design of treatments and vaccines .
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Chinese scholars and overseas collaborators have made progress in the asymmetric cross Diels Alder reaction
Time of Update: 2021-11-14
The team used electron-deficient 2-pyrones and non-activated cyclic conjugated dienes as dienes, catalyzed by copper and chiral oxazoline ligands, to achieve a pericyclic selective asymmetric cross-DA reaction , Provides a new idea for the construction of functionalized chiral bicyclic structure, and based on this methodology, completed the high-efficiency asymmetric total synthesis of the biologically active molecules artemisinin and coronatine .
