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What should I do if angular cheilitis is always bad?
Time of Update: 2022-05-09
Especially during the epidemic, regardless of whether there is any problem of angular cheilitis, it is always correct to keep a bottle of 21 Jinvita multivitamin tablets to supplement the nutritional deficiency caused by uneven diet.
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《PNAS》Solutions for Lymph Node Aging
Time of Update: 2022-05-09
The investigation, led by Janko Nikolich, found that lymph nodes, which are critical for maintaining and accelerating immune responses during infection, age at different rates .
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Gao Shaorong/Jiang Cizhong's research group cooperated to reveal the mechanism of in vitro fertilization technology affecting the development of extraembryonic tissue
Time of Update: 2022-05-09
Gao Shaorong's group and Jiang Cizhong's group from Tongji University's School of Life Science and Technology published a research titled "Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos" online in Cell Reports on May 5 .
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Novel electronically controlled gene expression tool
Time of Update: 2022-05-09
"As part of this project, we have created tools that will allow researchers to use electrical signals to control the gene expression and behavior of cells without any loss of performance .
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"Science" How many steps does it take to accurately transform normal cells into cancer cells?
Time of Update: 2022-05-09
Single-cell RNA sequencing revealed that these cells gradually altered their gene expression programs as more genetic mutations were introduced, and that mouse tumor models had similar gene expression patterns and pigmentation patterns to human melanoma patients with the same genotype .
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Bayer's Nubeqa Receives FDA Priority Review for the Treatment of mHSPC
Time of Update: 2022-05-09
S. Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for Nubeqa (darolutamide) in combination with chemotherapy in patients with metastatic hormone-sensitive prostate cancer (mHSPC) .
Based on positive data from the Phase 3 ARASENS trial, Bayer raised Nubeqa's peak annual sales, which it expects to reach 3 billion euros .
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Repair tendons with silk protein
Time of Update: 2022-05-09
To improve the tissue regeneration capacity of the scaffolds, the team then paired silk fibroin with GelMA, a gelatin-based water-retaining gel, due to GelMA's biocompatibility, degradability, stiffness, and properties that promote cell attachment and growth ability .
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Mao Youdong's team "Nature" published a breakthrough technology to crack the key mechanism of protein degradation
Time of Update: 2022-05-09
▲ One of the atomic structural models of the degradation of polyubiquitinated substrates by the proteasome complex under the regulation of USP14 (A), time-resolution cryo-EM analysis of the temporal evolution of the statistical distribution of the 13 intermediate states with the process of protein degradation (B) (picture Source: Professor Mao Youdong/CC BY 4.
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"Journal of Hepatology" Pfizer's new crown vaccine latest side effects: or lead to hepatitis cirrhosis liver failure?
Time of Update: 2022-05-09
The latest clinical research from Germany found:COVID-19 mRNA vaccine (BNT162b2) jointly developed by Pfizer and BioNTech may cause rare T cell-mediated autoimmune hepatitis!
The study found that male patients developed jaundice 10 days after the first injection of the mRNA vaccine, and liver function tests (LFT) showed acute mixed hepatocellular/cholestatic hepatitis .
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Gene therapy reverses effects of autism-related brain organoid mutations
Time of Update: 2022-05-09
A series of experiments showed that mutations in TCF4 lead to dysregulation of the downstream SOX gene and the Wnt pathway, two important molecular signals that guide embryonic cells to proliferate, mature into neurons and migrate to their correct locations in the brain .
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Scientists discover new target for solid tumor CAR-T therapy
Time of Update: 2022-05-09
Moffitt researchers are working to identify tumor markers that will make CAR-T an effective treatment for patients with solid tumors .
Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors .
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Peking University scholar Hearing Research published a paper revealing the attentional regulation of perceptual space effect on prepulse inhibition and its related neural mechanisms
Time of Update: 2022-05-09
Recently, Hearing Research published a new article "Perceptual Spatial Position Induces the Attentional Enhancement of Prepulse Inhibition and its Neural Mechanism" by Professor Li Liang and his Ph. D.
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Guangdong Professor Xi Ruiyan helps you solve the problem of calorie balance
Time of Update: 2022-05-09
a-Al inhibits the activities of various amylases in the gastrointestinal tract related to starch absorption, so that a large amount of carbohydrates in food are mainly absorbed at the end of the small intestine, thereby prolonging the digestion time of food in the intestinal tract and causing the body to absorb glucose rate decreased .
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'Voice-controlled' enzymatic reaction
Time of Update: 2022-05-09
They dubbed this audible-sound-generated solution transient domain "pseudo-compartmentation" and used it to control an enzyme-based cascade reaction network in solution .
In this phenomenon, the fluids produced in the container vibrating up and down due to audible sound do not mix with each other around the nodes of the wave, so the solutions are naturally separated .
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A technology for real-time detection of anxiety states based on multimodal physiological signals
Time of Update: 2022-05-09
In a recent work published in the journal Frontiers in Psychiatry, the team of Professor Zhi Yang, a researcher at the Tianqiao Brain Research Institute (TCCI) and the Center for Mental Health Affiliated to Shanghai Jiaotong University School of Medicine, revealed a high temporal resolution State anxiety tracking model .
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Zhang Yuquan's research group from Shanghai Jiaotong University published the research results of suburban agricultural modeling in the high-level comprehensive journal Fundamental Research
Time of Update: 2022-05-09
Recently, the research group of Associate Professor Zhang Yuquan of the Sino-British International Low-Carbon School of Shanghai Jiao Tong University published a research paper entitled "Operating pesticide use reduction within the boundary of food security in peri-urban settings" in Fundamental Research, a high-level and high-level comprehensive journal .
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A Molecular Mechanism of High IgM Immunodeficiency
Time of Update: 2022-05-09
Words for Java 18. 9" >In the adaptive immune system, the diversity of antibody molecules produced by B lymphocytes is the key effector molecule in mediating humoral immunity. Therefore, the diversi
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The latest review of Nanjing Agricultural University: Virus-host interaction network as a new target for anti-IAV and anti-SARS-CoV-2 drugs
Time of Update: 2022-05-09
Ping Jihui from the School of Veterinary Medicine of Nanjing Agricultural University published an online publication entitled "Virus-host interaction networks as new antiviral drug targets for IAV" in the international academic journal "Emerging Microbes & Infections" (IF=7.
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The role of the cerebellum in absence epilepsy
Time of Update: 2022-05-09
Cerebellar stimulation for abnormal brain activityResearchers at the University of Bochum studied mice that developed absence seizures due to a lack of P/q-type calcium channels in cerebellar nerve cells .
This allowed the researchers to slowly increase the activity of cerebellar nuclei, preventing further swd in the mice .
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Comprehensive regional diagnosis of marine microorganisms using DNA testing
Time of Update: 2022-05-09
James' advisor, Andrew Allen, started the effort, called the NOAA CalCOFI Marine Genomics Project (NCOG), in 2014, starting with water samples collected during the iconic CalCOFI survey cruise, which has been around since 1949.
