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Sound is widely used in physics, materials science, etc.
Later, they took a closer look at the motion of the solution caused by the audible sound and found that due to the nodal regions of the wave, the solution was separated rather than mixed together, as if the different layers were blocked by an invisible wall
The new discovery inspired the research team to use this phenomenon to attempt spatiotemporal control of multistep enzymatic reactions
To test the system, Kim's team performed a multi-step enzymatic reaction consisting of glucose oxidase (GOx) and horseradish peroxidase (HRP)
As expected, the authors were able to observe the cyan concentric ring pattern with the naked eye, confirming their successful spatiotemporal control of the GOx-HRP cascade using only audible sounds
Director Kim explained, "This new approach using audible sound will provide a novel and reliable strategy to control chemical processes in predictable, instantaneously generated pseudo-compartments of solutions
Prabhu Dhasaiyan, Tanwistha Ghosh, Hong-Guen Lee, Yeonsang Lee, Ilha Hwang, Rahul Dev Mukhopadhyay, Kyeng Min Park, Seungwon Shin, In Seok Kang, Kimoon Kim.