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Scientists discover chemical marker that could unlock future therapeutic uses of mRNA
Time of Update: 2022-05-13
In animals, including humans, the mRNA is called the AUG start codon and plays a role in protein production, the universal codon for the "zipper" of RNA genes .
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The CDC estimates that more than three-quarters of children in the United States have been infected with the coronavirus, and the infection rate of the elderly is lower
Time of Update: 2022-05-13
About 34 percent of Americans of all ages had signs of infection in December .
Studies have shown that previous infections can protect some people from serious illness and hospitalization, but CDC officials stressed that people who were previously infected should still get the COVID-19 vaccine .
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Suzhou Medical Institute has made research progress in high-sensitivity enhanced Raman sensing technology
Time of Update: 2022-05-13
In this work, the researchers took two volatile organic gases, putrescine and cadaverine, as examples to verify the detection performance of the three-dimensional flexible SERS substrate in gas sensing .
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Nature Cancer: Reprogrammed macrophages stimulate vascular cells to secrete proteins and promote cancer metastasis
Time of Update: 2022-05-13
The team's experiments in mice transplanted with human breast cancer cells showed that the reprogrammed macrophages stimulated vascular cells to secrete a mix of metastasis-promoting proteins that are part of the metastatic niche .
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The latest article published by Peking University's Nature: Unraveling the structure of human PBAF chromatin remodeling complex bound to nucleosomes
Time of Update: 2022-05-13
On April 27, 2022, the Joint Center for Life Sciences, the School of Life Sciences of Tsinghua University, the Advanced Innovation Center for Structural Biology, Zhucheng Chen, and the research team published online in the journal Nature entitled "Human-derived PBAF chromatin remodeling complex.
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How Equal Charges in Enzymes Control Biochemical Reactions
Time of Update: 2022-05-13
Professor Kai Tittmann's team at the Göttingen Center for Molecular Biosciences (GZMB) has now succeeded for the first time using protein crystallography to obtain structural snapshots of substrates shortly before chemical reactions .
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The role of metabolic signaling in the prevention of atrial fibrillation
Time of Update: 2022-05-13
(C) Typical in vivo ECG (lead II) of atrial AMPK-dKO mice at 6 weeks of age showing normal sinus rhythm and atrial fibrillation .
, associate professor, the Young lab demonstrated the detrimental effects of AMPK gene deletion on the molecular, electrical, and structural remodeling of the atrium, ultimately leading to persistent atrial fibrillation .
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Newly discovered protein in fungi bypasses plant defenses
Time of Update: 2022-05-13
Scientists from the USDA Agricultural Research Service and Washington State University have discovered a protein that allows the fungus that causes stem rot of white mold in more than 600 plants to overcome the plant's defenses .
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New evidence on how exercise fights diabetes damage
Time of Update: 2022-05-13
Now, for the first time, MCG scientists have evidence that even 45 minutes of moderate-intensity exercise in the face of diabetes can cause more exosomes, submicroscopic packages filled with biologically active substances, to deliver directly to these cells Deliver more of the protein, ATP7A, which can initiate angiogenesis, they report in the journal FASEB .
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The Lancet: More than 70% of COVID-19 patients still have sequelae a year later
Time of Update: 2022-05-13
A study of more than 2,000 hospitalized patients with COVID-19 showed that only 29% fully recovered one year after contracting COVID-19, and 71% had sequelae, the most common sequelae being fatigue, muscle pain, slow movement, sleep Bad and breathing difficulties .
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Scientists discover chemically-induced fear memory suppression mechanism
Time of Update: 2022-05-13
The study's first author, Ayako Kawaminami, who is currently conducting research at American University, said: "Our selective DOP antagonist for preconditioning can antagonize the effects of KNT-127 on BLA and IL .
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Yale University: Cancer origins from endogenous, exogenous and preventable mutational processes
Time of Update: 2022-05-13
Jeffrey Townsend, the Elihu Professor of Biostatistics in YSPH's Department of Biostatistics, said studying examples of specific genetic mutations could reveal the extent to which preventable exposures, such as UV light, contribute to tumor growth in 24 cancers .
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eLife: Gene variants associated with mobility changes during aging
Time of Update: 2022-05-13
S. Health and Retirement Study (HRS) to see if the genetic equivalent of the ALDH4A1 gene variant in humans was also associated with age-related changes in mobility .
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The team of Academician Kangle reveals a new mechanism of piRNAs regulation that determines the changes in the number of offspring of migratory locusts
Time of Update: 2022-05-13
This study also suggests that the novel mechanism of Piwi/piRNAs-mediated mRNA splicing of coding genes found in migratory locusts may also be common in other animals to regulate reproductive strategies .
The regulatory mechanism of Piwi/piRNAs-mediated pre-mRNA splicing on reproductive function-related genes was revealed .
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Nano flu vaccine protects against seasonal flu
Time of Update: 2022-05-13
The new nanoparticle vaccine contains the same four hemagglutinin proteins as the commercial quadrivalent influenza vaccine and produces the same or better response to the vaccine-matched strain in mice, ferrets and non-human primates as the commercial vaccine , which can neutralize the antibody response .
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Important progress has been made in the research on the mechanism of the activation of novel small molecules by the communication between the fungi where microorganisms are located
Time of Update: 2022-05-13
mso-bidi-font-family:Helvetica'>Yin Wenbing's research group at the Institute of Microbiology, Chinese Academy of Sciences has been working on the gene regulation mechanism and function of fungal secondary metabolites .
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An epigenetic cause of miscarriage found and cured
Time of Update: 2022-05-13
In previous research, they found that blocking these instructions led to prenatal death, especially in male embryos, and also to an enlarged placenta in the mother .
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Previously unknown risk factors for leukemia in adults
Time of Update: 2022-05-13
Cancer researchers from the University Medical Center Schleswig-Holstein (UKSH), Kiel Campus and the Kiel University Medical School describe improvements in a new research paper on the genetic causes of acute lymphoblastic leukemia (ALL) Approaches to the treatment of adult blood cancer patients .
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The team of Professor Mao Youdong from the School of Physics has made a breakthrough in the reconstruction of protein dynamics regulation by artificial intelligence-assisted time-resolved cryo-EM
Time of Update: 2022-05-13
Words for Java 18. 9" >The team of Professor Mao Youdong, Institute of Condensed Matter Physics and Materials Physics, School of Physics, Peking University, State Key Laboratory of Artificial Microstr
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Cell: A new era of mitochondrial genome editing has begun
Time of Update: 2022-05-13
"As such, reliable techniques for editing mitochondrial DNA are one of the last frontiers of genome engineering, which must be explored in order to conquer all known genetic diseases, and which the world's most elite scientists have worked hard to make a reality for years .
