The Lancet: More than 70% of COVID-19 patients still have sequelae a year later

"The Lancet": One year after discharge of new coronary pneumonia patients, more than 70% of patients still have sequelae

The new coronavirus usually infects the human body through the respiratory tract, causing damage to the respiratory system and various organs of the human body

The new crown pneumonia epidemic is still raging around the world, causing huge negative impacts on the world economy and society

Two years after the outbreak, we have realized that COVID-19 is not only a respiratory disease, but also affects multiple tissues and organs of the human body

For example, it affects the central nervous system, causing loss of smell and taste, fatigue, cognitive decline, and, in some patients, stroke and more severe disturbances of consciousness

There are even studies reporting that some young adults develop symptoms associated with Parkinson's disease after contracting COVID-19, as part of the so-called COVID-19 sequelae

Researchers from the University of Leicester in the UK published a prospective observational study in The Lancet

A study of more than 2,000 hospitalized patients with COVID-19 showed that only 29% fully recovered one year after contracting COVID-19, and 71% had sequelae, the most common sequelae being fatigue, muscle pain, slow movement, sleep Bad and breathing difficulties

For the study, researchers analysed patients from 39 UK National Health Service (NHS) hospitals, including 2,320 adult participants, 807 of whom were discharged from hospital between 7 March 2020 and 18 April 2021 Participants (32.

The mean age was 59 years, 279 patients (36%) were female, and 28% received invasive mechanical ventilation

Recovery was assessed using patient-reported outcomes, physical performance, and organ function at 5 months and 1 year after discharge

During the five-month visit, the researchers also took blood samples from the participants and analyzed them for the presence of various inflammatory proteins

Statistical analysis found that 25.

The study found that compared with men, women were 32 percent less likely to make a full recovery; those who were obese were 50 percent less likely to make a full recovery; and those who required mechanical ventilation were 58 percent less likely to make a full recovery

The results showed that women, obesity and patients on mechanical ventilation in the hospital were all less likely to make a full recovery after a year

The limited recovery in symptoms, mental health, exercise capacity, organ damage and quality of life between five months and one year of hospitalization in the study was striking, the researchers said

They also highlighted that being female and obesity were major risk factors for not recovering after 1 year, as being female and obesity were associated with more severe persistent health impairments, including decreased exercise performance and health-related quality of life

With a lack of treatment for COVID-19 sequelae, the findings highlight the urgent need for medical services to support this large and rapidly growing patient population with many symptoms, including decreased exercise capacity and health-related quality of life within a year.
dropped sharply afterwards
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Without effective treatments, COVID-19 sequelae could become a highly prevalent new long-term disease, researchers say
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Reference: https://doi.
org/10.
1016/S2213-2600(22)00127-8