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Previously unknown risk factors for leukemia in adults

 Last Update: 2022-05-13
 Source: Internet
 Author: User

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Cancer researchers from the University Medical Center Schleswig-Holstein (UKSH), Kiel Campus and the Kiel University Medical School describe improvements in a new research paper on the genetic causes of acute lymphoblastic leukemia (ALL) Approaches to the treatment of adult blood cancer patients

Clinicians and researchers, led by Prof.

Diversity of genetic causes of disease

BCP-ALL is associated with various risk-related genetic alterations that can manifest at the molecular level as distinct subtypes of the disease

"For the first time, we have used a new machine-learning-based approach to characterize new molecular subtypes of BCP-ALL through so-called gene expression profiles," explains Baldus, first author of the new study

"Detection of these genetic alterations in patients provides a method for early diagnosis of this leukemia subtype

Need for more precise treatments

New findings suggest that chemotherapy has limited efficacy in this subtype of BCP-ALL

Bringing new leukemia therapies to the clinic

"The new findings provide an important contribution to improving precision tumor diagnosis and treatment of acute lymphoblastic leukemia

Courtesy of Keele University

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