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Cell Stem Cell: Thyroid hormone found to be a missing ingredient in lab-made liver cells
Time of Update: 2022-05-17
However, the researchers found that while the stem cell-derived liver cells produced the right amount of THRB, something prevented it from binding where it should and performing its function .
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Some autism spectrum disorder symptoms linked to astrocytes
Time of Update: 2022-05-17
Abnormalities in a type of brain cell called astrocytes may play a key role in causing certain behavioral symptoms of autism spectrum disorder, according to a preclinical study by Weill Cornell Medicine researchers .
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Lv Haitao's research group from the Institute of Systems Biomedicine, Shanghai Jiao Tong University, together with the teams from Xi'an Jiaotong University and the University of Macau, published a review of the frontiers of treatment strategies for IBD
Time of Update: 2022-05-17
Recently, Haitao Lv's research group from the Institute of Systems Biomedicine, Shanghai Jiaotong University, in collaboration with teams from Xi'an Jiaotong University and the University of Macau, pu
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New progress in drug research on fish enterohepatic inflammation
Time of Update: 2022-05-17
According to the above drug prediction results of fish enterohepatic inflammation, sea buckthorn was added to the feed to evaluate its anti-enterohepatic inflammation effect in the zebrafish foodborne enteritis model ( SBMIE ) model (patent authorized), Using immune gene expression analysis, immune cell imaging, pathological and growth evaluation, multi-omics analysis (transcriptome and microbiome) and other methods, the molecular immune mechanism of sea buckthorn against intestinal liver inflammation was revealed .
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The research group of Wu Aibo and Hu Qiannan of the Institute of Nutrition and Health jointly published a review paper on the biogenic safety control of mycotoxin deoxynivalenol
Time of Update: 2022-05-17
On April 8, 2022, researcher Wu Aibo and researcher Hu Qiannan of Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences jointly published an online publication entitled "Elimination of Fusarium mycotoxin deoxynivalenol (DON) via microbial and enzymatic strategies in the international academic journal Trends in Food Science & Technology.
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Nature sub-journal: Enteroviromics can predict disease
Time of Update: 2022-05-17
The viral signature highlighted in the study, along with changes in gut bacterial communities, could provide early warning signs that infants are at risk for NEC, allowing clinicians to take urgent action .
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Injectable stem cell assembly for cartilage regeneration
Time of Update: 2022-05-17
Ki-Bum Lee from Rutgers University, and Prof.
They established an injectable hybrid inorganic (IHI) nanoscaffold-templated stem cell assembly and applied it to the regeneration of critical-size cartilage defects .
Injectable Hybrid Inorganic Nanoscaffold-templated Rapid Stem Cell Assembly for Accelerated Cartilage Repair
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The molecular mechanism of the chromatin remodeling complex regulating the higher-order structure of chromosomes
Time of Update: 2022-05-17
On April 22, 2022, Zhou Yue's research group from the State Key Laboratory of Protein and Plant Gene Research, the School of Modern Agriculture of Peking University, and the Peking University-Tsinghua University Life Science Joint Center published an online article entitled "Chromatin remodeling complexes" on The Plant Cell.
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COVID-19 can directly infect and damage human kidney cells
Time of Update: 2022-05-16
"To test their podocyte model with the real SARS-CoV-2 virus, Musah and Kalejaiye collaborated with Maria Blasi, an assistant professor of medicine at Duke University and a researcher at the Duke Human Vaccine Institute .
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New study analyzes complete genetic blueprint of more than 18,000 cancer samples, uncovers new mutational patterns
Time of Update: 2022-05-16
Scientists have analyzed the complete genetic blueprint of more than 18,000 cancer samples, uncovering new mutational patterns that could help doctors deliver better, more personalized treatments .
To help doctors use this information, the researchers developed a computer algorithm that allows them to find common mutational patterns and pick out rare ones .
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A small mutation may make Zika more dangerous
Time of Update: 2022-05-16
"Shresta added: "The Zika virus variant we found has evolved to the point where the cross-protective immunity from previous dengue infections is no longer effective in mice .
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Preliminary study finds organic vegetables contaminated with widespread pathogenic microorganisms
Time of Update: 2022-05-16
New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Lisbon, Portugal (April 23), shows that the pathogenic amoeba that lives in organic vegetables can shelter human pathogens such as Pseudomonas, Salmonella, Helicobacter pylori and a potential risk to public health .
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New Nature Methods software improves identification of cancer-causing DNA variants
Time of Update: 2022-05-16
"Understanding cancer requires identifying genetic changes that force a patient's healthy cells to grow uncontrollably," said Assistant Professor Ryan Layer .
STIX uses secondary analysis techniques to search the raw data from thousands of samples, looking for any evidence that supports the presence of variants in each specific tumor .
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Renhe Yeast Science Book: Specializing in Chinese People's Health Problems and Creating Natural Herbal Products
Time of Update: 2022-05-16
Renhe Yenkeshu series products contain herbal fermented liquid, which is guided by the basic theory of traditional Chinese medicine, adopts intangible cultural heritage processing techniques, "medicine and food homologous" herbs as raw materials, and the principle of compatibility between monarchs, ministers, ministers and envoys.
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Hospitalized patients with COVID-19 have much higher mortality rates than seasonal flu patients
Time of Update: 2022-05-16
Although adults hospitalized with COVID-19 are younger and have fewer chronic diseases, they are at higher risk of complications and death than flu patients, according to a retrospective cohort study conducted at the Hospital del Mar in Barcelona .
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Dong Wenfei's team from Suzhou Institute of Medical Technology reveals the light-emitting mechanism of carbon dots
Time of Update: 2022-05-16
In the present study, the authors isolated o-phenylenediamine carbon dots ( o-pd CDs ) by column chromatography and confirmed two precise molecular fluorophore structures, 2 , 3 -diaminophenazine ( DAP ) and 2 -Amino- 3 -hydroxyphenazine ( AHP ) .
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Human calcium channel CaV3.3 gating mechanism and drug recognition mechanism
Time of Update: 2022-05-16
Combined with electrophysiological experiments, the structural elements that regulate the activation of T-type calcium channels at low voltage were identified for the first time .
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Radioactive iodine treatment increases risk of new cancers, more at risk in younger adults
Time of Update: 2022-05-16
Kitahara's team from the National Cancer Institute used the SEER database to assess the risk of solid SPM in differentiated thyroid cancer patients treated with RAI before age 45 .
High risk associated with solid thyroxine m, especially in patients with differentiated thyroid cancer aged <25 years .
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Nature Communications: Novel mechanism of PD-L1 regulation by RNA-binding protein DENR
Time of Update: 2022-05-16
Expression for tumor immune evasion research paper, which revealed a new mechanism by which RNA-binding protein-translation re-initiation factor DENR regulates the expression of PD-L1 by promoting the protein translation of JAK2 and the JAK2-STAT1 signaling pathway, thereby participating in the process of tumor immune evasion .
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How to Reduce Your Risk of Colorectal Cancer
Time of Update: 2022-05-16
Causes of colorectal cancer include a lack of dietary fiber, too much fat, too much processed meat, not enough exercise, obesity, smoking, and alcohol consumption .
Lower your risk of colon cancer by eating whole foods consisting of unprocessed grains, fruits, vegetables, seeds, nuts, and lean proteins such as fish or white meat .