-
Crit Care: Serum neural wire assays improve clinical risk scores for outcome prediction in patients with cardiac arrest
Time of Update: 2021-01-31
A recent study found that serum nerve wire light chain (NfL) levels in patients with cardiac arrest were closely associated with poor nerve prognosis.
the researchers calculated two clinical risk scores (OHCA and CAHP) and measured the subjects' NfL levels within 24 hours of hospitalization using a single-molecule array NF-light experiment.
-
Neurology: Bone density is closely related to small vascular disease
Time of Update: 2021-01-31
, several studies have found a positive correlation between increased arterial stiffness and the burden of brain SVD.
decreased bone density is associated with increased vascular calcification and arteriosclerosis, which can aggravate arterial stiffness and end-of-life organ damage throughout the body.
-
JNNP: Relationship between sub-tumor-related marginal encephalitis and olive nuclear degeneration under hypertrophobicity
Time of Update: 2021-01-31
identified six patients, all clinically diagnosed as sub-tumor encephalitis, which developed into HOD during the course of the disease.
clinically highly suspected patients with sub-tumor encephalitis, 3t or 7t MRIs may be more sensitive in detecting HOD and DROP lesions, but further research is needed to determine this.
-
Heart: Incidence and predictive factors of stroke in patients with rheummatoid heart disease
Time of Update: 2021-01-31
recently, a study published in Heart, an authoritative journal in the field of cardiology, aimed at assessing the incidence and predictive factors of stroke in RHD patients.
atrial fibrillation on stroke risk assessment is influenced by death as a competitive risk.
-
ATVB: The new table of cartilage oligopolymer protein is a new biomarker of symptomatic cervical artery stenosis
Time of Update: 2021-01-31
recently, Arteriosclerosis, Thrombosis, andVascular Biology, an authoritative journal in the field of cardiovascular medicine, published a study in which researchers looked at whether comPtotal and COMPneo, as well as other cardiovascular markers and clinical parameters, can identify symptomatic cervical artery stenosis.
-
JCEM: Relationship between blood sugar control and cognitive function in patients with cavity gap stroke with diabetes
Time of Update: 2021-01-31
In 942 patients with diabetic cavity gap stroke who participated in the Secondary Prevention (SPS3) trial of small cortical stroke (ClinicalTrials.gov, NCT00059306), the researchers assessed the effects of baseline and follow-up A1C on cognitive assessment screening tool (CASI) score baseline values and changes over time.
-
JNNP: Model study of cascading changes in GRN-related temporal lobe dementia biomarkers
Time of Update: 2021-01-31
study, DEBM was used to assess the time cascade of changes in biomarkers before and during symptomatic FTD-GRN mutation carriers, distinguishing between early and late biomarkers.
bvFTD patients, biomarker sequencing also indicates that language and NfL are the earliest abnormal biomarkers.
-
Neurology: In patients with mild cognitive impairment, amyloid-β deposits were lower and dopamine activity decreased
Time of Update: 2021-01-31
, Qin Chen and others at Huaxi Hospital, Sichuan University, explored the relationship between amyloid-β-PET and dopamine transporter imaging (123I-FP-CIT SPECT) and clinical ideotypes in MCI-LB patients.
amyloid-β PET and 123I-FP-CIT SPECT complement each other in describing clinical esoploids in MCI-LB patients.
-
Neurology: Antioxidants in the diet may reduce the risk of Parkinson's disease
Time of Update: 2021-01-31
important for this study is that it suggests that dietary intake of vitamins E and C may be inversely related to the risk of Parkinson's disease, but not with β-carotene or NEAC in the diet.
-
Neurology: PET's new image score can help predict the risk of Alzheimer's disease
Time of Update: 2021-01-31
in the A-T-group, the ADCRP score is a significant predictor of dementia (for each additional z-score, HR is 2.02, p significance of this study is the discovery that the ADCRP score is a valuable biomarker of neurodegeneration, the subject of mild cognitive impairment and biologically defined Alzheimer's disease.
-
Aging Cell: Removing systemic senescing cells relieves inflammation and cognitive impairment in the brain
Time of Update: 2021-01-31
in mouse models of neurodegenerative diseases, removing senescing cells has been shown to improve brain function.
it observed an increase in age dependence on p16Ink4a senescing cells, which is more pronounced in small glial cells and less progeny glial cell progeny cells, which are characterized by the secretion of SASP.
-
Lancet Neurology: Patisiran treats the long-term safety and effectiveness of multiple neuropathic amyloid changes mediated by hereditary thyroxine delivery proteins
Time of Update: 2021-01-31
summary, the overall results of the 12-month mid-term data analysis of the global OLE study showed that Patisiran had ongoing benefits for patients with multiple neuropathic amyloid changes mediated by hereditary thyroxine delivery proteins.
-
JAHA: Choose medium to high intensity exercise to prevent dementia more effectively! Especially men
Time of Update: 2021-01-31
results found that high blood pressure, hyperlipidemia, diabetes and other risk factors for cognitive decline, the specific data can be found in the table below: Fourth, the prevention of delayed dementia, recommended exercise strategies to prevent dementia, or delay the onset of dementia, will effectively extend the life expectancy of patients, reduce disability rates, reduce health care costs, and improve the quality of life.
-
Annals of Neurology: a predictive factor for postoperative motor performance in people with Parkinson's disease, deep brain stimulation
Time of Update: 2021-01-31
Francesco Cavallieri and others at the university hospital, based on their follow-up queues, focused on long-term exercise results after receiving deep core stimulation (STN-DBS) in patients with Parkinson's disease (PD) and analyzed their preoperative predictive factors.
-
Neurology: A new drug for multiple sclerosis that slows brain atrophy
Time of Update: 2021-01-29
PRINT-MS, conducted by Robert T Naismith of the University of Washington and others, was a 96-week clinical phase 2, placebo-controlled, multi-center, randomized, double-blind, parallel group trial designed to assess the efficacy and safety of Iudilast's treatment of primary and secondary progressive MS at doses of 60 to 100 mg per day.
-
Neurology: A study of 300,000 people revealed cancer incidence and mortality in people with multiple sclerosis
Time of Update: 2021-01-29
University of Canada and others, who used population-based data sources to compare the incidence of MS and matching queues and cancer-specific mortality rates, looked at whether cancer risk was different in patients with multiple sclerosis (MS) and non-MS patients.
-
Neurology: A new follow-up study shows that one in ten patients with new crowns has neurological disorders
Time of Update: 2021-01-29
conducted a forward-looking, multi-center, observational study based on adults who were hospitalized continuously in the New York City metropolitan area, and looked forward to the incidence of specific neurological disorders, comparing the similarity and differences between COVID-19 patients with or without neurological symptoms, as well as related complications and discharges.
-
JNNP: Different potential characteristics of neuromediation, physical and psychosocial functions of former NFL players: A long-term NFL study
Time of Update: 2021-01-29
Potential Profile Analysis (LPA) is an empirical approach that is ideal for identifying different subgroups of former professional American football players and their relationship to RHI (years of participation) and cumulative concussions, as it classifys individuals based on unmeased potential cesarean sections of various symptom structures.
-
Neurology: MrI characteristics of cerebrovascular disease do not improve the ability to predict stroke outcomes
Time of Update: 2021-01-29
origin of the original Cerebral Small Vessel Disease MRI Features Do Not Improve the Prediction of Stroke Outcome; Juliette Coutureau, et al.
-
The experimental drug donanemab for Alzheimer's disease shows great hope for treatment
Time of Update: 2021-01-27
The rate of mental decline in patients who were infused with the experimental drug around them slowed by 32 percent, and after 6-12 months of treatment with the donanemab drug, the patient's body no longer carried β amyloid plaques, a hallmark of Alzheimer's disease.
