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Ischemic stroke is a serious complication in patients with rheummatoid heart disease (RHD), which can lead to permanent disability and death.
recently, a study published in Heart, an authoritative journal in the field of cardiology, aimed at assessing the incidence and predictive factors of stroke in RHD patients.
selected patients diagnosed with RHD with clinical and echo cardiology.
a structured clinical and neurological assessment of the subjects when they were in the group to determine the cause and classification of stroke.
main endpoint of the study was ischemic cerebrovascular events, including fatal or non-fatal strokes.
researchers assessed stroke risk and considered competitive risk.
the study included 515 patients, of whom 438 (85%) were women and 46±12 years old.
most common valve lesions are mixed di tip valve lesions (80%).
group, 92 patients (18%) had previous strokes, the most common being precirculation infarction (72%).
in an average of 3.9 years of follow-up, 27 patients (5.2%) had a stroke, with a total rate of 1.47 per 100 patients per year.
that the Cox model predicts stroke include past strokes (after correction HR is 5.395, 95% CI is 2.272-12.811), age (HR is 1.591, 95% CI is 1.116-2.269) and baseline atrial fibrillation (HR is 2.945, 95% CI is 1.083-8.007).
AF's impact on stroke risk is reduced by using death as a competitive risk (HR is 2.287, 95% CI is 0.962-5.441).
result, 5.2% of patients in this large group of RHD patients have a stroke, which can be predicted by age, atrial fibrillation and past stroke.
atrial fibrillation on stroke risk assessment is influenced by death as a competitive risk.