-
Xintai Pharmaceutical's Oxiracetam injection was approved for marketing
Time of Update: 2021-03-25
According to data from Meinenet, the terminal sales of Oxiracetam in China's public medical institutions have continued to decline in recent years, from 8 billion yuan in 2016 to 5.
In 2020H1, the sales of Oxiracetam in China's public medical institutions exceeded 1 billion yuan, a year-on-year decline of 57.
-
Sci Adv︱ The latest evidence that neurodevelopmental defects cause juvenile Parkinson's disease: patients with DNAJC6 mutations have neurodevelopmental defects and neurodegenerative phenotypes in the brains
Time of Update: 2021-03-24
And explore the mystery of neuroscience with rigorous academic and logical thinking︱Editor by Wang Sizhen︱Wang Sizhen Parkinson’s disease (PD) is a common neurodegenerative disease characterized by t
-
Neuron | Moving or not, you have to listen to the GO-STOP signal!
Time of Update: 2021-03-24
March 3, 2021 (advanced online) The Ueli Rutishauser research team of neurosurgery at Cedar Sinai Medical Center in the United States published an article in Neuron for the first time to record the firing of fast-moving and stopped-moving neurons in the human subthalamic nucleus at the single-cell level.
-
In addition to being refreshing, spicy food can also mobilize hematopoietic stem cells!
Time of Update: 2021-03-24
Pain nerves are also related to bone marrow, but can these neurons also mobilize hematopoietic stem cells?
The original article was published under the title Pain-sensing neurons mobilize blood stem cells from bone marrow in the News and Views section of Nature on December 23, 2020 © naturedoi: 10.
-
Interpretation of Science Sub-Journals!
Time of Update: 2021-03-24
Louis School of Medicine and other research institutions have identified a kind of amyloid plaques in the brain tissue and blood vessels that can be removed in mice without increasing bioon.
-
Interpretation!
Time of Update: 2021-03-24
Acta NeuropathologicaIn this study, the researchers identified a type of RNA that could serve as a potential therapeutic target for developing treatments for Huntington's disease; this sRNAs molecule does not encode proteins, but is very important for regulating gene expression; the researchers said SRNAs may be involved in the pathogenesis of Huntington's disease.
-
The use of β-blocker drugs—propranolol may be expected to repair vascular malformations in the brain!
Time of Update: 2021-03-24
February 28, 2021 // --Recently, a research report titled "Propranolol Reduces the Development of Lesions and Rescues Barrier Function in Cerebral Cavernous Malformations" was published in the international magazine Stroke , from Uppsala University Scientists from other institutions have discovered through research that beta blockers may help repair abnormal blood vessels in the brain.
-
npj Digital Medicine: Research shows that irregular sleep is associated with bad mood and depression
Time of Update: 2021-03-24
February 22, 2021--In a new study, scientists from the University of Michigan Academic Medical Center analyzed the sleep and mood data of more than 2,100 early-career doctors in one year and showed that , Irregular sleep, like lack of overall sleep time or frequent staying up late, will increase the risk of long-term depression.
-
Today, humans can scan 1 million neurons in real time: a new breakthrough in brain cell activity imaging technology
Time of Update: 2021-03-24
In this paper, the researchers proposed Light Beads Microscopy (LBM), which is a scalable and optimal acquisition method in time and space, limited only by fluorescence lifetime, in which a set of axially separated and time-different focal points The entire axial imaging range is recorded almost at the same time, so that volume measurement can be recorded at a speed of 1.
-
Experts comment on Nat Methods | Luo Qingming's team developed line illumination modulation microscopy to achieve high-definition imaging
Time of Update: 2021-03-24
Fluorescence microscopy optical slice tomography (fMOST) technology developed by the team of Academician Luo Qingming of Huazhong University of Science and Technology and continuously updated iteratively is the only one in the world that can be used to achieve whole-brain-scale single-cell connection resolution mesoscopic brain mapping.
-
Moss cells just to remember more meticulously?
Time of Update: 2021-03-24
After the low-separation mode mice require more inversions to complete the experiment correctly, memory The extraction efficiency is reduced, which indicates that the precise spatial memory is impaired after inhibiting the activity of moss cells.
This indicates that SST neurons projected by moss cells to the granular cell layer can regulate precise memory.
-
Reveal the molecular mechanism of light-activated brain neuron expression!
Time of Update: 2021-03-24
February 28, 2021 // - Recently, an article was published in the international magazine Scientific Reports entitled Competition between cyclization and unusual Norrish type I and type II nitro-acyl migration pathways in the photouncaging of 1-acyl-7- In the research report "nitroindoline revealed by computations", scientists from Florida University of Technology and other institutions have revealed how light activates brain neurons.
-
Chinese scientists deeply analyze dopamine and provide new ideas for neurological disease drug research and development | Cell Press Dialogue Scientist
Time of Update: 2021-03-24
In February 2021, the journal Cell of the Cell Publishing House of Life science published two related studies from Chinese scientists.
They are "Structural insights into the human D1 and D2 dopamine receptor signaling" by Xu Huaqiang's team at Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
-
An apple a day, the strongest brain is close to me!
Time of Update: 2021-03-24
They found that apple peel is rich in quercetin, which can Promote the survival of hippocampal precursor cells and neuron differentiation in adult mice, and the abundant 3,5-dihydroxybenzoic acid in the pulp has the function of significantly increasing neural precursor cell proliferation and neurogenesis.
-
Nature | Make learning easier, scientists reveal that new experiences can restart neural circuits to promote learning
Time of Update: 2021-03-24
Gordon research team of the Department of Psychiatry at Columbia University published an article in the journal Nature and found that exposure to new environments or experiences inhibits the synaptic connections established in the hippocampus and prefrontal cortex, and promotes new development in mice.
-
University of Science and Technology Liu Qiang team reveals a new mechanism of Alzheimer's disease caused by ApoE4 | CellPress Dialogue Scientist
Time of Update: 2021-03-24
Life sciences Life science recently, the team of Professor Liu Qiang from the University of Science and Technology of China published a research paper entitled "Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory" in Neuron magazine, revealing the origin of astrocytes The mechanism by which ApoE reprograms the cholesterol metabolism of neurons, and the effect of this metabolic regulation on neuronal function, especially the process of learning and memory.
-
Stuttering: Maybe it’s not a stumbling life
Time of Update: 2021-03-24
Maguire, professor and chair of the Department of Psychiatry and Neuroscience, UCR School of Medicine, published an article titled Investigation of Risperidone Treatment Associated With Enhanced Brain Activity in Patients Who Stutter in Frontiers in Neuroscience, which combined functional neuroimaging It is found that “risperidone”, a drug previously designated for schizophrenia and bipolar disorder, may have a certain effect on stuttering, and its mechanism of action may be similar to that of the stellate in the striatum of the brain.
-
Cell Stem Cell: Up-regulating the expression of lamin B1 makes aging neural stem cells rejuvenate
Time of Update: 2021-03-24
com/tags/%E5%B9%B2%E7%BB%86%E8%83%9E/">stem cells lose the ability to proliferate and produce new neurons, which leads to a decline in memory function.
html">stem cellJessberger said, "Although our research is limited to neural stem cells in the brain, when it comes to the aging process of other bioon.
-
JBC: Study reveals targets for treating stroke
Time of Update: 2021-03-24
html">Scientists discover target for stroke therapy in blood-brain barrierOriginal source: Kenta Ko et al, Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure , Journal of Biological Chemistry (2020).
-
PNAS: Significant progress!
Time of Update: 2021-03-24
Benjamin Wolozin, Professor of Pharmacology and Experimental Therapeutics at Boston University School of Medicine, explained, “We found that droplets containing the RNA-binding protein TIA1 related to AD (and amyotrophic lateral sclerosis) form toxic tau.
