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In February 2021, the journal Cell of the Cell Publishing House of Life science published two related studies from Chinese scientists.
They are "Structural insights into the human D1 and D2 dopamine receptor signaling" by Xu Huaqiang's team at Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
complexes" and "Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes" by Shao Zhenhua’s team from West China Hospital of Sichuan University, respectively, expounded the molecular understanding of dopamine signaling, the ligand recognition, activation mechanism and signal transduction of dopamine receptors.
select.
It provides a variety of structural templates for the design of drugs for the dopaminergic system, and also lays an important foundation for the development of therapeutic drugs for neurological diseases.
The WeChat public account of Cell Press interviewed the author teams of these two papers and interpreted the papers, aiming to share the research results and some future prospects with the majority of scientific researchers.
They are "Structural insights into the human D1 and D2 dopamine receptor signaling" by Xu Huaqiang's team at Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
complexes" and "Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes" by Shao Zhenhua’s team from West China Hospital of Sichuan University, respectively, expounded the molecular understanding of dopamine signaling, the ligand recognition, activation mechanism and signal transduction of dopamine receptors.
select.
It provides a variety of structural templates for the design of drugs for the dopaminergic system, and also lays an important foundation for the development of therapeutic drugs for neurological diseases.
The WeChat public account of Cell Press interviewed the author teams of these two papers and interpreted the papers, aiming to share the research results and some future prospects with the majority of scientific researchers.
