-
JACC study: To prevent dementia, pay attention to cardiovascular health as early as possible, blood pressure is especially important!
Time of Update: 2021-03-27
(Image source: Reference [1]) Studies have shown that among asymptomatic middle-aged people, assessed by the 30-year Framingham heart risk score, cardiovascular risk factors are related to low brain metabolism, and hypertension shows the strongest association .
-
Cell Stem Cell Back-to-Back | The Devil Hidden in Children's Brain——New Insights into the Mechanism of H3.3G34R Mutant Glioma
Time of Update: 2021-03-27
Recently, Cell magazine published a back-to-back report from the Viviane Tabar team at the Memorial Sloan Kettering Cancer Center in the United States entitled Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.
-
STROKE AF study: It is also necessary for patients with non-cardiac stroke to undergo long-term cardiac monitoring? 丨ISC2021
Time of Update: 2021-03-27
Patients with ischemic stroke caused by large atherosclerosis (LAA) or small vessel occlusion (SVO) usually do not receive long-term monitoring of atrial fibrillation (AF), and relevant secondary prevention guidelines do not recommend this approach.
-
One article summary: treatment of hepatic encephalopathy | clinical essential
Time of Update: 2021-03-27
For patients with hepatic encephalopathy grades 3 and 4, the recommended non-protein energy intake is 104.
-
Nat Comm | Zhang Xiaolong/Liu Xianguo collaborate to reveal the regulatory mechanism of thermal nociception
Time of Update: 2021-03-27
Recently, Associate Professor Zhang Xiaolong of the Medical Research Center of Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) and Professor Liu Xianguo of the Pain Research Center of Sun Yat-sen University jointly published a research paper entitled ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking in Nature Communications It was found that ATF4 binds to ion channel TRPM3 and kinesin KIF17, and the three form a complex.
-
"Microorganisms": Scientists have discovered for the first time that improving intestinal bacteria can promote the recovery of nerve function after spinal cord injury | Gutjun Weekly
Time of Update: 2021-03-27
How intestinal bacteria change the brain | Gut Jun Weekly Issue 154: A sub-issue of Nature, for the first time!
The largest study to date on the characteristics of intestinal bacteria, gender and age in the Han population in northern China | Changjun Jun Weekly Issue 153: "Digestive Diseases and Science" heavyweight!
-
Why is it "was awakened by heat"? Han Junhai's team reveals the neural mechanism of environmental temperature regulation of sleep
Time of Update: 2021-03-27
On March 19, 2021, the Han Junhai team of Southeast University published an online title in the Cell sub-Journal Current Biology: This study reveals the neural circuits that mediate temperature regulation of sleep, and brings a new science to the interpretation of the above problems Perspective.
-
The thrombolysis time window can be extended to 9 hours, and it is suitable for stroke after waking up!
Time of Update: 2021-03-27
The study showed that thrombolysis within 6 hours of ischemic stroke improved the patient’s functional outcome; In the early stage, patients in the thrombolytic group within 6 hours had a higher risk of symptomatic intracranial hemorrhage and death from cerebrovascular disease.
-
International Stroke Conference: The era of tenecteplase intravenous thrombolysis has really come?
Time of Update: 2021-03-27
Last year, Professor Steven Warach and Professor Jeffrey Saver published an article in JAMA Neurology that tenecteplase used for stroke thrombolytic therapy can reduce the transmission of emergency new crowns and alleviate the shortage of alteplase [2], and summarized tenecteplase in detail.
-
The first oral medicine for spinal muscular atrophy (SMA)! Roche Evrysdi treatment can improve or maintain motor function for 2 years. It has been under review in China!
Time of Update: 2021-03-27
SUNFISH is a global placebo-controlled study that is evaluating the oral drug Evrysdi (risdiplam) for the treatment of type 2 or bedridden type 3 spinal muscular atrophy (SMA) patients aged 2-25 years.
-
Children’s epilepsy should be diagnosed and treated sooner rather than later, and guard the "electric little angel" with love
Time of Update: 2021-03-27
The treatment of epilepsy in children needs special attention, and strive to control seizures before the language development period of 4-5 years old, so as to win precious language development opportunities for children.
More than 60% of childhood-onset patients can effectively control epileptic seizures and return to normal life through standardized treatment and rational drug use.
-
The BMI1 gene prevents Alzheimer’s disease by inhibiting the production of four-stranded DNA in neurons
Time of Update: 2021-03-27
In this Nature Communications paper, the research team found that G-quadruplex structures accumulate in the brain neurons of Alzheimer's patients, but not in the brains of healthy elderly people.
-
Cell interpretation! Scientists are expected to use the human body's gut microbiome to develop new targeted therapies for the treatment of neurological diseases!
Time of Update: 2021-03-27
A few days ago, in a research report titled "Dissecting the contribution of host genetics and the microbiome in complex behaviors" published in the international journal Cell , scientists from Baylor College of Medicine and other institutions in the United States have discovered through research that microbes in the gut may be It will induce certain disease symptoms related to complex neurological diseases, so microbial-based therapies may be expected to help treat human neurological diseases in the future.
-
How is insomnia diagnosed? Teach you hand in hand!
Time of Update: 2021-03-27
B. Obtain the specific content of the patient's sleep status: manifestations of insomnia, work and rest time, sleep-related symptoms, and the impact of insomnia on daytime functions.
-
Are there differences in the prognosis of patients with large vessel occlusive stroke? Gender Difference丨ISC2021
Time of Update: 2021-03-27
➤The independent rate of discharge function between the two groups was similar in average (IQR) mRS scores (39% for women vs 46% for men, p=0.
Figure 1 depicts the distribution of MRS scores at discharge, and the 90-day follow-up stratified by gender, A) overall EVT cohort, and B) propensity pairing.
-
Can CT perfusion imaging be used to screen patients with stroke endovascular treatment? ——Results from the MR CLEAN study丨ISC2021
Time of Update: 2021-03-27
conducted a study to evaluate the correlation between the ischemic core and penumbra volume assessed by CTP and functional outcome in patients undergoing EVT in current clinical practice.
Yimaitong compiled from: CT Perfusion-Guided Patient Selection for Endovascular Treatment of Acute Ischemic Stroke: Results From the MR CLEAN Registry.
-
The patient has repeated dizziness and fainting many times because of this disease!
Time of Update: 2021-03-27
6fl (reference value 82-100fl), average hemoglobin volume 36.
Doctor station medication query to solve your doubts, director rounds and questions, no longer afraid to obtain vitamin drugs, guidelines, only three steps to query medication 1.
-
Mouse brain can directly metabolize alcohol | "Nature-Metabolism" paper
Time of Update: 2021-03-27
A study published in "Nature-Metabolism", Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication, showed that in mice, alcoholism may affect the behavior of the brain rather than the alcohol breakdown products (metabolites) produced by the brain rather than the liver.
-
Current Biology | Han Junhai's team reveals the neural mechanism of environmental temperature regulation of sleep
Time of Update: 2021-03-27
On March 18, 2021, the Han Junhai research team of Southeast University published an online article A subset of DN1p neurons integrates thermosensory inputs to promote wakefulness via CNMa singaling in Current Biology, revealing the neural circuits that mediate temperature regulation of sleep, which is the answer to the above problems.
-
Two-in-one, scientists have discovered that a single wavelength can achieve multi-color, deep three-photon imaging technology
Time of Update: 2021-03-27
Whether it is imaging a variety of different red fluorescent dyes or brain regions at different depths, the image signal-to-noise ratio obtained at the excitation wavelength at 1340nm is the best.
