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JAMA Pediatr: The effect of hypertension during pregnancy on the neurodevelopmental outcome of offspring
Time of Update: 2021-03-30
Recently, researchers investigated hypertension in pregnancy Relationship with autism spectrum disorder, attention deficit/hyperactivity disorder and intellectual disability in the offspring, and to investigate its impact on the overall cognitive performance of the offspring.
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J Alzheimers Dis: Exercise can promote blood flow in the brain
Time of Update: 2021-03-30
Journal of Alzheimer's Disease, 2021 One-Year Aerobic Exercise Reduced Carotid Arterial Stiffness and Increased Cerebral Blood Flow in Amnestic Mild Cognitive Impairment.
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Neurology: Beware of air pollution, the risk of dementia after exposure to PM2.5 increases significantly in old age
Time of Update: 2021-03-30
5 Associated With Gray Matter Atrophy Reflecting Increased Alzheimer Risk in Older Women neurology.
5 Associated With Gray Matter Atrophy Reflecting Increased Alzheimer Risk in Older Women neurology.
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Stroke: The influence of delirium and its subtypes on stroke outcome
Time of Update: 2021-03-30
Although delirium is common in stroke patients, there is a lack of studies evaluating the correlation between clinical subtypes of delirium and functional outcomes and death.
The main outcome of the study was functional dependence or death at 90 days between delirium patients and non-delirium patients and subtypes (modified Rankin scale> 2).
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Nat Commun: Intraciliary transport decreases with age, impairing sensation and metabolism
Time of Update: 2021-03-30
They reported that due to the reduction of IFT components regulated by daf-19/RFX , the intrafellar transport (IFT) of sensory neurons in elderly nematodes was impaired.
The study found that up - regulation of daf-19/RFX can effectively enhance IFT , sensory perception, AMPK activity and autophagy, and promote metabolic homeostasis and longevity .
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The Chen Gong team of Jinan University developed anti-cancer gene therapy: directly transforming gliomas into neurons
Time of Update: 2021-03-27
Chen Gong, a former professor at Pennsylvania State University and now director of the Brain Repair Center of Jinan University in China, has developed a new type of gene therapy that can reprogram glioma cells into functional neurons, which can provide for the treatment of gliomas.
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Science Review ︱tau Protein: Promoters of Brain Diseases and Targeted Therapy Strategies
Time of Update: 2021-03-27
The author reviewed the progress in the study of tau protein mechanisms in brain diseases, and explored scientific ideas and approaches to promote field research and drug development.
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The children of the stars are no longer alone! New study discovers new ways to improve responsiveness of children with autism
Time of Update: 2021-03-27
Researchers from the University of Ottawa School of Medicine found that by increasing the norepinephrine in the motor cortex, the mice's motor skills improved faster, hoping to provide a new idea for helping children with autism.
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NEJM: Inner ear implant device improves daily balance and quality of life in patients with vestibular dysfunction
Time of Update: 2021-03-27
This study is the first to show in daily life that artificial implantation devices have significantly improved the patient's balance, gait stability and quality of life through long-term follow-up, marking an important new development in the field of vestibular medicine.
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PNAS interpretation! How do immune cells in the blood affect the brain health of patients during early Parkinson's disease?
Time of Update: 2021-03-27
Recently, an article was published in the international journal PNAS entitled "Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder In the research report, scientists from Aarhus University and other institutions have revealed the mysterious relationship between Parkinson’s disease and specific immune cells in the blood through research.
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ISC gives 4 recommendations for blood pressure management in acute ischemic stroke!
Time of Update: 2021-03-27
02 Blood pressure management after stroke thrombolysis Figure 2: From the lecturer's courseware For acute ischemic stroke patients who are suitable for intravenous thrombolysis, their blood pressure should be reduced to below 185/110mmHg before and within 24 hours after treatment.
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Surveillance of stroke condition, a list of recommendations from the consensus of Chinese multidisciplinary experts! 丨Guide consensus
Time of Update: 2021-03-27
➤ It is recommended to use it in combination with other monitoring methods such as intracranial pressure/CPP to obtain more accurate disease assessment and prognosis prediction (level B evidence, category IIa recommendation).
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Qiangbin Wang Research Group of Suzhou Institute of Nanotechnology, Chinese Academy of Sciences AM: Nanomedicine-mediated stem cell therapy for Alzheimer’s disease
Time of Update: 2021-03-27
Wang Qiangbin's research team from the Suzhou Institute of Nanotechnology, Chinese Academy of Sciences has developed a multifunctional neural stem cell (NSC) treatment strategy that combines genes, nanomedicine and stem cells to achieve continuous Aβ clearance and promote nerve regeneration and repair in a mouse model, showing good improvements The efficacy of memory and cognition in AD mice.
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Tsinghua University Shi Songhai’s team discovered the process of neuroglia in the neocortex of the brain | Cell Press Dialogue Scientist
Time of Update: 2021-03-27
Life science On March 16, 2021, Shi Songhai's team from the School of Life Sciences, Tsinghua University, and Benjamin D.
Procedures and suggest that the abnormal behavior of glial precursor cells is related to the occurrence of glioma.
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MR CLEAN-NO IV Study: Can anterior circulation stroke bypass intravenous thrombolysis and directly use endovascular treatment? 丨ISC2020
Time of Update: 2021-03-27
The MR CLEAN-NO IV trial aims to evaluate the effectiveness and safety of direct EVT and bridging therapy (IVT+EVT) in patients with AIS caused by anterior circulation occlusion.
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How to carry out neuroprotective treatment? These 4 stages are critical
Time of Update: 2021-03-27
Improving cerebral blood circulation and neuroprotection are the main treatment measures for acute ischemic stroke [1].
Multi-pronged, neuroprotective treatment of acute ischemic stroke through multiple mechanisms is brain tissue damage caused by cerebrovascular occlusion.
Neuroprotective effects of minocycline on ischemic stroke[J].
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Cell Metab | The brain regulation mechanism behind "gluttony"
Time of Update: 2021-03-27
On the basis of neural circuit research methods, it is revealed that a type of specific Nos1-expressing neurons that project from the insular cortex to the central amygdala promotes the neural mechanism of overfeeding, so as to better help us understand the specific environment The neurobiological mechanism behind "bulimia" behavior.
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Will atrial fibrillation increase the incidence of symptomatic intracranial hemorrhage after treatment in acute stroke patients? 丨ISC2021
Time of Update: 2021-03-27
The purpose of this study was to compare the incidence of symptomatic intracranial hemorrhage (sICH) in patients with and without a history of atrial fibrillation who received intravenous recombinant tissue plasminogen activator (IV rt-PA) and/or EVT.
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Neuron: Research reveals the different effects of dopamine on pain perception in men and women
Time of Update: 2021-03-27
Thomas Kash of the UNC School of Medicine shows that neurons use dopamine to regulate pain in male and female mice with different characteristics.
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How to achieve greater benefits when antiplatelet therapy is used for secondary stroke prevention? These two points are very important
Time of Update: 2021-03-27
Data from the SOCRATES study The THALES study is an international multi-center clinical trial that included more than 11,000 patients with mild acute ischemic stroke or high-risk TIA who started treatment within 24 hours after the onset of symptoms.
