-
Why can animals avoid predators?
Time of Update: 2021-05-09
After injecting AAV-GCaMP6s into the PMd brain area, the researchers embedded Grins lens to achieve calcium imaging in the deep brain area, and recorded the activity of CCK neurons in three escape models of rat threat, heating blanket, and high-concentration carbon dioxide.
-
Nat Neurosci︱GWAS analysis reveals a new gene (new protein) that has a clear causal relationship with depression
Time of Update: 2021-05-09
And using rigorous academic and logical thinking to explore the mysteries of neuroscience. Written by Wang Sizhen, edited by Wang Sizhen. Depression is a common mental illness. However, current tr
-
What are the risk factors for hospitalization within 30 days after endovascular treatment?
Time of Update: 2021-05-09
In order to determine the readmission rate and related factors within 30 days after endovascular treatment of patients with ischemic stroke, Dr.
Research conclusions In this large-scale nationally representative study, about 1 in 10 patients with acute ischemic stroke who received endovascular treatment were re-admitted to the hospital within 30 days after discharge.
-
Nat Commun | Luo Fujun's team reveals that neurexins regulates the aggregation and function of G-protein coupled GABAB receptors in the presynaptic active area
Time of Update: 2021-05-09
On April 22, 2021, the Luo Fujun team and the Stanford University Thomas Südhof team once again collaborated to publish an article Neurexins regulate presynaptic GABAB-receptors at central synapses in Nature Communications, revealing the positioning and function of Neurexins in regulating presynaptic GABAB receptors Plays an important role.
-
Protein & Cell | Yang Jing's team reveals a new immunomodulatory effect on degenerative diseases of the enteric nervous system
Time of Update: 2021-05-09
In response to the above-mentioned research gaps, on April 19, 2021, Jing Yang’s research group published an article (research long article) Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon in Protein & Cell, revealing acute The phenomenon of catecholaminergic neurodegeneration in the intestine under inflammatory conditions, and explained that this neuropathological phenomenon is controlled by the SARM1 signaling pathway and unexpectedly exerts a protective function against the disease.
-
Science latest: single-cell interaction sequencing technology reveals the communication code between glial cells
Time of Update: 2021-05-09
In summary, this article has discovered two signaling molecular pathways that "talk" between microglia and astrocytes through the development of a new cell-interacting single-cell sequencing technology RABID-seq: EphB3-Ephrin-B3 and Sema4D-PlexinB2.
-
Elderly men dance on the right side for 1 week. What are the reasons?
Time of Update: 2021-05-09
Brief medical history: admitted to the hospital due to dance of the right limb for 1 week.
56mmol/L; 2 hours postprandial blood glucose: 28.
Click to enter the mini program, check the answer, and enter the mini program below [Yimaitong case exchange] to learn and discuss with your comrades!
-
Cell | Prefrontal deep projection neurons are monitored through continuous feedback to achieve cognitive flexibility
Time of Update: 2021-05-09
In order to study the contribution of the projection target specificity to the functional heterogeneity of PFC neurons during fixed transfer, the authors tested the PFC-VMS and PFC-MDT two sets of projection neurons that have been reported in previous work to support cognitive flexibility.
-
Indifferent talk | talk about the indifference of Parkinson's disease patients
Time of Update: 2021-05-09
According to the neurology guidelines/expert consensus, apathy refers to a state of reduced motivation, which is clinically manifested as a decrease in goal-oriented behavior and a decrease in different degrees of interest and emotion, and it is not due to a decline in consciousness, nor is it a cognitive impairment or Caused by mood disorders [1].
-
Sudden dizziness and nystagmus, the course of the disease was twists and turns, the cause was unexpected by the director
Time of Update: 2021-05-09
The patient developed bilateral peripheral facial paralysis soon after the onset of dizziness, weakened tendon reflexes, separated cerebrospinal fluid protein cells, and positive serum peripheral neuropathy series antibodies, all supporting GBS.
-
The staged diagnosis and intervention measures of Alzheimer's disease are absolutely dry!
Time of Update: 2021-05-09
According to the "2018 Chinese Guidelines for the Diagnosis and Treatment of Dementia and Cognitive Impairment (6): Pre-Dementia in Alzheimer's Disease", the NIA-AA standard recommends more detailed staging and description of the preclinical stage, including the normal group and SNAP The group (suspected non-AD group) is more suitable for the development of pre-clinical AD research.
-
How does HR-NICE antiplatelet therapy go smoothly?
Time of Update: 2021-05-09
The 2014 edition of the "Guidelines for the Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack in China" recommends that acute non-cardiogenic TIA or mild type with a high risk of stroke recurrence (ABCD2 score ≥ 4) within 24 hours of onset should be given as soon as possible Patients with ischemic stroke (NIHSS score ≤ 3 points) were treated with aspirin combined with clopidogrel for 21 days (Ⅰ, A).
-
What is the relationship between good or bad grades and changes in brain activity?
Time of Update: 2021-05-09
In order to answer the above questions, a research team from Princeton University in the United States used magnetic resonance imaging to examine the brain images of 24 undergraduate students studying the general part of the computer science course, and found that the neural activity of a specific area of the student's brain is correlated with their test scores.
-
How to take medication for patients with epilepsy who have psychotic symptoms?
Time of Update: 2021-05-09
; on the other hand, it is necessary to consider the special characteristics of the symptoms of epilepsy patients, the interaction between antipsychotics and AED, and the possibility of increased risk of side effects.
-
Nature Sub-Journal: People who sleep less in middle age will increase the risk of dementia
Time of Update: 2021-05-09
The study analyzed the 25-year follow-up data of 7959 participants and reported that middle-aged and elderly people with long-term sleep less than 6 hours are associated with a 30% increased risk of dementia!
-
Cell Stem Cell | Anti-aging as early as possible—Mature brains have already appeared with molecular aging characteristics of neural stem cells
Time of Update: 2021-05-09
In summary, this study showed that short-term and long-term NSCs exhibit asynchronous depletion through clone tracing, and single-cell transcriptome analysis of deep neural stem cells in the resting phase revealed molecular aging characteristics in mature brains.
-
Stroke disease monitoring, see what the latest Chinese expert consensus says?
Time of Update: 2021-05-09
The application of electroencephalogram (EEG) monitoring to stroke patients can help determine the degree of consciousness coma and non-convulsive epileptic activities, and is used for the evaluation of brain damage (level B evidence, class IIa recommendation) .
Intracranial pressure monitoring is recommended for such patients (level B evidence, category IIa recommendation) .
-
Cell|Systematic exploration of the role of molecular chaperone autophagy in neurodegenerative diseases
Time of Update: 2021-05-09
The author systematically explored the unique role of CMA in the maintenance of nerve cell homeostasis and neurodegenerative diseases through proteomics and other methods, which is different from general macroautophagy.
After molecular chaperone autophagy is inhibited, protein degradation is abnormal and neuronal function is affected.
-
[Nature Sub-Journal] If middle-aged people lack sleep for a long time, will the risk of dementia increase?
Time of Update: 2021-05-09
Author: chen Introduction: Recently, researchers at the University of Paris in France took a different approach and used 25-year follow-up data to reveal the relationship between long-term lack of sleep in middle-aged people and the risk of dementia.
-
Why does a 7-year-old boy have sudden headaches, vomiting and confusion?
Time of Update: 2021-05-09
Recently, the clinical reasoning series of Neurology reported a case of acute headache, vomiting and confusion in a 7-year-old boy.
Further examination of multifocal stroke, sarcoma, and cardiac neoplasms requires testing for infection, coagulopathy, and malignant complications [such as tumor embolism, non-bacterial thrombotic endocarditis (NBTE)].
