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Severe skin reactions may increase the risk of death!
Time of Update: 2021-06-05
Research method This study collected 7 kinds of first prescriptions of carbamazepine, phenytoin, oxcarbazepine, lamotrigine, zonisamide, levetiracetam and topiramate in the Korean medical insurance database from January 2012 to December 2018 All patient data of antiepileptic drugs are used for correlation analysis of the incidence of SCARs.
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FGF13 gene participates in the regulation of mouse hippocampus development research progresses
Time of Update: 2021-06-05
The study found that the expression level of FGF13 gene in the neural stem cells of the hippocampal dentate gyrus of mice after birth showed a downward trend with the growth of developmental age.
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"Mannitol" and "glycerol fructose" are both commonly used drugs for lowering intracranial pressure. What are the differences?
Time of Update: 2021-06-05
At present, the commonly used clinical drugs for lowering intracranial pressure are mannitol, glycerol fructose, diuretics, hormones, etc.
Protect kidney function, reduce the occurrence of electrolyte disturbances, but also overcome the rebound phenomenon of intracranial pressure of mannitol, and improve the safety of clinical medication.
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The "active braking system" hidden around the amygdala-scientists have found this type of neuron
Time of Update: 2021-06-05
They further recorded the changes in the calcium ion activity of dm-ITC and vm-ITC during different stages of fear memory training, and found that the proportion of neurons that responded to dm-ITC during the above process was about 42.
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Sci Adv | Wu Qi's team reports a novel dopamine loop that reduces obesity and weight by enhancing satiety
Time of Update: 2021-06-05
Editor | Enzyme Beauty Just like every good story has a beginning, a climax, and an end, the animal instinctive behavior of foraging consists of a trilogy that includes the beginning, the continuatio
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This article will help you avoid misdiagnosis of stroke in the emergency room |
Time of Update: 2021-06-05
However, in addition to stroke, migraines, seizures, and other conditions may also cause patients to go to the neurological emergency department, and may be confused with stroke.
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After the car accident, the man with brain trauma insisted on going home. Fortunately, he met the doctor in charge...
Time of Update: 2021-06-05
Figure 3: Schematic diagram and CT findings of subdural hematoma 3 Subarachnoid hemorrhage Subarachnoid hemorrhage (SAH) refers to a type of clinical symptoms caused by blood flowing into the subarachnoid space after a blood vessel ruptures at the bottom of the brain or on the surface of the brain Intracranial hemorrhage.
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The 14-year-old boy has sudden weakness and headache. What are the reasons?
Time of Update: 2021-06-05
The differential diagnosis of acute weakness and weakened reflexes includes trauma (such as spinal shock, acute nerve injury), side infections [such as acute inflammatory demyelinating multiple radiculopathy (AIDP)] and direct infection [such as polio virus, West Nile virus, acute flaccid myelitis (AFM)].
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"Nature" Sub-Journal: No matter how difficult it is for a poor family to have a son?
Time of Update: 2021-06-05
It has been reported in the literature that family income and parental education are significantly related to the thickness of the prefrontal cortex in children and adolescents [4]; the more common risk of lead exposure (RLE) in poor areas is related to low intelligence [5].
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Professor Peter Rothwell: Low-dose aspirin for secondary stroke prevention | OCC 2021
Time of Update: 2021-06-05
. Studies have shown that compared with the control group, acute aspirin alone can significantly reduce the risk of stroke recurrence after TIA and ischemic stroke (0-6 weeks, P<0.
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How to break through the bottleneck of dementia treatment?
Time of Update: 2021-06-05
Studies have shown that brain imaging of plaques, and the levels of Aβ protein or tau protein in blood or cerebrospinal fluid, have certain value in predicting Alzheimer's disease several years in advance.
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Nature's contribution lasted for 5 years | The "sheriff" in the brain: Natural antisense transcripts can participate in the regulation of disordered protein stability related to neurodegeneration
Time of Update: 2021-06-05
Studies have reported that MAPT-AS1 contains an embedded mammalian-wide interspersed repeat (MIR), which can compete with the ribosomal entry site of MAPT mRNA to compete for ribosomal RNA pairing to inhibit tau protein translation, indicating MAPT-AS1 plays a key role in tau proteinopathy and reveals the potential broad contribution of MIR-NATs to the strict control of translation of IDPs, especially related to protein stability in neurodegeneration.
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Liu Guanghui/Wang Si/Qu Jing's research group collaborated to reveal the molecular mechanism of primate hippocampus aging
Time of Update: 2021-06-05
In order to further clarify the cellular and molecular changes in the aging process of primate hippocampus, the researchers used high-precision mononuclear transcriptome sequencing technology to comprehensively and systematically reveal the neural stem cells, transient amplified progenitor cells (TAPC), and immature neurons.
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Real world research adds new evidence!
Time of Update: 2021-06-05
It was demonstrated in a RWS: Teri-Pro study [9]: A real-world phase IV study (n=1000) that mainly explored the outcome of patient reports including treatment satisfaction, using the Drug Therapy Satisfaction Questionnaire (TSQM, including Effectiveness, adverse reactions, convenience, and overall satisfaction) when evaluating, MS patients received teriflunomide treatment for 48 weeks after the average TSQM overall satisfaction score is at a high level (68.
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Nature Sub-Journal: Reactivate the "paralyzed" immune system and launch an attack on deadly brain cancer
Time of Update: 2021-06-05
To this end, researchers have developed an innovative treatment to reactivate the "paralyzed" immune system against tumors, that is, to fight gliomas through therapeutic vaccines or immunotherapy.
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Attached expert comment: Scientists have revealed the mechanism by which neuronal activity promotes tumor growth, which is originally related to it
Time of Update: 2021-06-05
In order to study the effect of neuronal activity on the growth of low-grade glioma and the formation of glioma, they used a type of optic neuroma called poorly differentiated, which has Nf1-OPG transgenic mice with high tumor incidence.
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"Nature": A major breakthrough in Alzheimer's disease immunotherapy!
Time of Update: 2021-06-05
In addition, the researchers found another important neuroinflammation pathological manifestation of AD during the observation of the pathological process of amyloid in mice: the ablation of meningeal lymphatic vessels can cause abnormal activation of microglia in AD mice.
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Can we reverse aging by plugging our "brain holes"?
Time of Update: 2021-06-05
We want to know whether the physical and mental stress brought by the war to the soldiers will cause damage to the blood-brain barrier to some extent, so we chose to force the mice to swim to test our ideas.
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Express | It is expected to benefit 95% of migraine patients!
Time of Update: 2021-06-05
▎ WuXi AppTec content team editor May 27, 2021, Biohaven Pharmaceuticals announced that the US FDA has approved its small molecule CGRP receptor inhibitor Nurtec oral disintegrating tablets (rimegepant 75 mg) for extended indications for paroxysmal migraine Preventive treatment (less than 15 migraine attacks per month).
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"Rethinking" the use of anti-epileptic drugs after children with epilepsy are discharged from the hospital
Time of Update: 2021-06-05
A new study showed that after 24 months of age were treated with antiepileptic drugs (ASMs) in the hospital, there was no difference in functional neurodevelopment or epilepsy regardless of whether they continued to use ASMs after discharge.
