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One lesson to master 5 hot issues in women's epilepsy management
Time of Update: 2021-08-08
Therefore, even if there are no symptoms, women with epilepsy of childbearing age still need to take anti-epileptic drugs for disease control during pregnancy, and the blood concentration of ASM needs to be tested .
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Express US$360 million to help develop innovative treatments for Parkinson's disease, and Ipsen capsules obtain dopamine receptor antagonists
Time of Update: 2021-08-08
This innovative therapy is currently being tested in a phase 2b clinical trial for the treatment of dyskinesias in patients with Parkinson's disease after receiving levodopa treatment .
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The patient has drooping eyelids for 1 year and has positive acetylcholine receptor antibodies. What disease can you think of?
Time of Update: 2021-08-08
Physical examination: Drooping right eyelid, fixed right eyeball, bilateral pupils of equal size , Sensitive to light reflection, suspicious fatigue test, no abnormalities in the rest of the nervous system, no abnormalities in head MRI, no abnormalities in thymus CT, AchR(+) .
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"Annual Book of Neurology": Another heavyweight in the field of gut-brain axis!
Time of Update: 2021-08-08
Scientists have discovered that short-chain fatty acids play a key role in the effects of intestinal bacteria on the efficacy of immunotherapy | Intestinal Jun Weekly Issue 171: Intestinal bacteria have made significant progress in the treatment of inflammatory bowel disease!
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Consciousness disorder + drooping eyelids, what disease can you think of?
Time of Update: 2021-08-08
Considering that the patient’s ischemic cerebrovascular disease cannot be ruled out, the next step requires imaging examination: 12 hours after the onset of the patient’s brain MRI: abnormal signals in the bilateral thalamus.
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Science: Which eye's visual input do you prefer?
Time of Update: 2021-08-08
The researchers cultured immature astrocytes from the first day of life for ten days and transplanted them into the primary visual cortex of adult mice (3 months old) .
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Nat Commun Ji Jing's team discovered a new mechanism for prodynein to regulate neuronal death after traumatic brain injury
Time of Update: 2021-08-08
Figure 1 In summary, the team revealed the protective effect of Prok2 on neurons after traumatic brain injury, and further explained the importance of the Prok2-Fbxo10-Acsl4 regulatory axis in inhibiting neuronal iron death and the accompanying lipid peroxidation.
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Nature: The sequelae of new crown infection damage the brain, may affect life
Time of Update: 2021-08-08
According to the article, a large-sample population study conducted by FAIR Health found that nearly one-quarter of patients with new coronary disease are still suffering from long-term symptoms after being diagnosed for a month or more.
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Interview with Professor Li He: Several Key Issues in Lipid Management of Ischemic Stroke CSA & TISC 2021
Time of Update: 2021-08-08
From the perspective of clinical practice, in principle, medication should be used, even if it drops to a normal range, it should be treated, because this is a long-term preventive process, and lipid-lowering drugs can not only reduce the level of low-density lipoprotein cholesterol, it It also protects blood vessels and reduces inflammatory reactions, so as long as there are no side effects, stick to it .
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Express uses Nobel Prize discoveries to create protein degradation therapy, new sharp sword refers to neurodegenerative diseases
Time of Update: 2021-08-08
▲Schematic diagram of the mechanism of action of autophagosome binding compounds (picture source: reference [3]) PAQ will use the ATTEC technology platform to first focus on the development of therapeutics for neurodegenerative diseases, and may expand to a series of other treatment options with limited options Disease .
Retrieved July 15, 2021, from https:// launches-with-30-million-series-a-to-develop-novel-therapies-through-autophagy-dependent-degradation-301333970.
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New breakthrough in AI+ brain-computer interface!
Time of Update: 2021-08-08
In order to decode sentences based on Pancho's neural activity in the sentence task in real time, Chang et al.
The language detection model processes each time point of neural activity in the task and detects Pancho's attempts to speak words in real time .
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STTT Huazhong University of Science and Technology Wang Jianzhi team developed a new method to remove hyperphosphorylated tau, which can potentially treat diseases such as Alzheimer's
Time of Update: 2021-08-08
The study designed and synthesized a new type of dephosphorylation targeting chimera (DEPTAC) to specifically promote the binding of tau to protein phosphatase 2A (PP2A-Bα) containing the Bα subunit, which is the most active tau phosphate in the brain Enzyme .
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Express delivery effect lasted for 52 weeks, and long-acting complement inhibitor reached the primary phase 3 clinical endpoint
Time of Update: 2021-08-08
▎ WuXi AppTec content team editor July 15, 2021, Alexion Pharmaceuticals announced that in adults with systemic myasthenia gravis (gMG), its long-acting C5 complement inhibitor Ultomiris (ravulizumab) phase 3 clinical trial has achieved positive results .
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Wang Yongjun: Cerebrovascular disease research based on multiomics of stroke CSA & TISC 2021
Time of Update: 2021-08-08
With the development of new diagnosis and treatment technologies, the rate of death and disability of cerebrovascular diseases in the hospital is getting lower and lower, but residual recurrence and high disability are still major problems faced by ischemic cerebrovascular diseases .
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Important progress in the treatment of Alzheimer's disease!
Time of Update: 2021-08-08
In other words, even if there are amyloid deposits and neurofibrillary tangles, as long as the "forest fires" that do not cause neuroinflammation, Alzheimer's disease may be controlled .
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What should I do if hemorrhage changes after thrombolysis?
Time of Update: 2021-08-08
In 1994, Levy used the concept and definition of "symptomatic intracranial hemorrhage" for the first time in the study of intravenous thrombolysis, linking cerebral hemorrhage after recanalization of acute cerebral infarction with clinical symptoms .
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CSA & TISC 2021 Professor Li Xiaogang Interview: Combined with non-statin lipid-lowering program to promote ischemic stroke lipid-lowering standards
Time of Update: 2021-08-08
Introduction At present, the secondary prevention of ischemic stroke in China has limited benefits based on the current treatment plan.
Yimaitong: At present, the effect of statins for lipid-lowering treatment is limited.
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Acute Ischemic Stroke Obtains New Evidence from China to Help Realize "Healthy China 2030"
Time of Update: 2021-08-08
In October 2020, based on the results of large-scale confirmatory clinical studies after the market, the new indication of Cinepazide Maleate injection was approved by the National Medical Products Administration: used to improve neurological symptoms caused by acute ischemic stroke , Activities of daily living and dysfunction .
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Fishing nemesis?
Time of Update: 2021-08-08
The study found that slow waves, a pattern of neural activity usually associated with transitions to sleep, can be used to predict whether people will daydream or have brain blanks, and their response to the environment .
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Nature: Astrocytes provide a powerful backing for the protection of microglia
Time of Update: 2021-08-08
However, in the brains of patients with AD (Alzheimer's disease), astrocytes and microglia are widely activated, secrete inflammatory factors and gather around Aβ protein plaques to play a protective role .
