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European Radiology: These small intracranial vascular diseases may not be as serious as you think!
Time of Update: 2022-09-14
Figure below: 90-day mRS distribution in patients with non-mild (0-2 points) versus moderate to severe total CSVD load (3-4 points).
This study found that a significant proportion of LVO-AIS patients who received EVT had moderate to severe overall CSVD loading.
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Science Sub-Journal: Revealing a novel electrical signal and its neural mechanism that maintains circadian rhythms
Time of Update: 2022-09-14
On September 2, 2022, the luo donggen team of Beijing University Graduate School, McGovern Brain Research Institute, Center for Quantitative Biology, and Peking University-Tsinghua Joint Center for Li
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Knowing that you will be fat and want to eat, the team of Zhou Yudong/Shen Yi of Zhejiang University reveals the neuroinflammatory mechanism of compulsive eating
Time of Update: 2022-09-10
This study revealed the neuroinflammatory mechanism of high-fat diet (HFD)-induced compulsive eating, and found that high-fat food increased the proliferation of microglia in the anterior paraventricular nucleus of the thalamus (aPVT), resulting in abnormal function of aPVT excitatory neurons, and then compulsive eating behavior .
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Sci Adv︱ Zhao Cunyou/Chen Rongqing's team reveals the mechanism of microRNA-induced social and memory abnormalities in mice: miR-501-3p expression deficiency enhances glutamatergic transmission
Time of Update: 2022-09-09
Written by Liang WenquanEditor in charge ︱ Wang SizhenEditor︱Yang BinweiSchizophrenia (SCZ) is a common type of severe mental illness with a prevalence of about 1%, involving abnormalities such as dis
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He Jing's team reviewed the research progress of neuroblastoma liquid biopsy
Time of Update: 2022-09-09
Recently, He Jing's research group from the Surgery Laboratory of Pediatric Research Institute of Guangzhou Women's and Children's Medical Center published a research paper entitled: Advances in liqui
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Sci Adv︱ Zhang Yi's research group discovered important neurons that regulate drug addiction behavior
Time of Update: 2022-09-09
In August 2022, Professor Zhang Yi's laboratory at Harvard Medical School-Boston Children's Hospital published a research titled "A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction" in the journal Science Advance, which systematically studied a Physiological functions and circuit mechanisms of neurons that are important regulators of addiction-related behaviors .
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"Nature" sub-issue: 20 minutes of brain stimulation a day, 4 days to reverse memory decline
Time of Update: 2022-09-09
In this study, a team of researchers from Boston University examined the effects of electrical brain stimulation on both types of memory in older adults .
In this study, a team of researchers from Boston University examined the effects of electrical brain stimulation on both types of memory in older adults .
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PLOS Biology Sleep can promote the development of modern civilization!
Time of Update: 2022-09-09
iNatureHumans helping each other is a prominent feature of Homo sapiens, and this basic feature has been one of the most powerful forces shaping the emergence of modern civilization . But what determi
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Cell: When you read this article, a group of neurons in your brain has been "lit up"
Time of Update: 2022-09-09
When Nancy Kanwisher studied the visual ventral pathway (the part of the brain that recognizes objects) more than two decades ago, she discovered that cortical regions respond selectively to the face.
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Intellia announces latest clinical follow-up data, in vivo CRISPR gene editing therapy has made further progress
Time of Update: 2022-09-09
August 28, 2022 / eMedClub News / -- Intellia Therapeutics and Regeneron Pharma Announce Phase 1 of their In vivo Genome Editing Candidate NTLA-2001 Single Dose for the Treatment of Transthyretin (ATTR) Amyloidosis Interim data from the experimental trial .
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Detecting disease through breathing while sleeping...Nature sub-issue: Artificial intelligence provides digital biomarkers for Parkinson's disease diagnosis
Time of Update: 2022-09-09
In the new study, the team developed a new artificial intelligence-based neural network model for detecting Parkinson's disease, predicting disease severity and tracking disease progression over time using nocturnal breathing, a characteristic of breathing during sleep progress .
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The prevalence rate is as high as 70%!
Time of Update: 2022-09-09
The current study, based on data from two cohorts of subjects in Spain, confirms that a Mediterranean lifestyle (combining good eating habits, physical activity/rest/social habits based on a Mediterranean dietary pattern) is associated with improved pain symptoms in the elderly population .
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Frontier "Nature" sub-issue: Classic melanoma drugs are expected to treat Alzheimer's disease?
Time of Update: 2022-09-09
▲If you have any business needs, please long press to scan the QR code above, or▎Edited by WuXi AppTec Content TeamAlzheimer's disease (AD) is the most common neurodegenerative disease in the elderly, characterized by cognitive impairment caused by synaptic loss and neuronal death, and extracellular amyloid beta plaques are one of its pathological hallmarks .
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Just one drink is enough to permanently change the brain | PNAS
Time of Update: 2022-09-09
Yi Ge is sent from the qubit of the concave temple | public account QbitAIIt turns out that after drinking for the first time in life, the brain has undergone permanent changes?Yes, people used to foc
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The main points of diagnosis and treatment of cognitive impairment after stroke are unclear?
Time of Update: 2022-09-09
*For medical professional reading reference onlyLet's listen to the big coffee's interpretation of the concept, diagnosis and treatment and prevention of PSCI!Globally, China has become the country wi
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Nature's annual release of depression "Blue Book" on the mechanism of depression
Time of Update: 2022-09-09
1038/d41586-022-02210-zThe pictures in the article are from the referenceClick on the blue word to follow us1 The vicious circle of depression and obesityThe intertwined and overlapping biological mechanisms between these two diseases act as causal factors, exacerbate each other's disease processes, and become trapped in a vicious cycle in which inflammatory factors and corticosterone are involved as key regulators .
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[Cell Sub-Journal] MIT's latest research: "gluttonous ghosts" neurons, see food and shine
Time of Update: 2022-09-09
This newly discovered population of food-responsive neurons is located in the ventral visual flow, along with those that respond specifically to faces, bodies, places, and words.
This newly discovered population of food-responsive neurons is located in the ventral visual flow, along with those that respond specifically to faces, bodies, places, and words.
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Bayer's new drug is approved for clinical use. Can AAV therapy become a new hope for the treatment of Huntington's disease?
Time of Update: 2022-09-09
After the report revealed that in a Phase 1/2 trial for Huntington's disease, 3 of 14 patients in the high-dose AMT-130 treatment group experienced serious side effects, the company said it was in agreement with the data safety monitoring committee ( DSMB) decided to suspend the administration of the high-dose group after consultation .
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The past, present and future of Professor Xiao Qin's levodopa
Time of Update: 2022-09-09
Parkinson's disease (PD) is a common movement disorder among middle-aged and elderly people, which seriously affects the quality of life of patients . With the aging of the Chinese population, the num
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Cell Biosci Wang Yongjun's research group reveals the molecular mechanism of D-type dopachrome isomerase-mediated inflammatory response in injured spinal cord
Time of Update: 2022-09-09
On August 14, 2022, the research group of Professor Wang Yongjun of Nantong University published a study entitled "D-dopachrome tautomerase drives astroglial inflammation via NF-κB signaling following spinal cord injury" in Cell & Bioscience This paper expounds the regulatory mechanism of D-DT as a pro-inflammatory factor mediating the inflammatory response of spinal cord astrocytes .
